2020
Pathologic nodal downstaging in men with clinically involved lymph nodes undergoing radical prostatectomy: Implications for definitive locoregional therapy
Ghali F, Daly W, Hansen M, Hayn M, Sammon J, Beaule L, Sarkar R, Murphy J, Kader A, Derweesh I, Rose B, Ryan S. Pathologic nodal downstaging in men with clinically involved lymph nodes undergoing radical prostatectomy: Implications for definitive locoregional therapy. Urologic Oncology Seminars And Original Investigations 2020, 39: 130.e1-130.e7. PMID: 33121914, DOI: 10.1016/j.urolonc.2020.08.035.Peer-Reviewed Original ResearchConceptsNodal statusRadical prostatectomyOverall survivalDiscordant stagingDiscordant statusSimilar OSLymph nodesClinical positive lymph nodesNational Cancer Data BaseClinical nodal stagingDefinitive locoregional therapyPathologic nodal statusUnderwent radical prostatectomyPositive lymph nodesPositive nodal statusLow Gleason scoreNegative node statusDifficult clinical scenariosKaplan-Meier estimationCharlson indexClinical nodalCM1 diseaseCT1-3Noncurative therapyPathologic nodal
2019
Prostatectomy in men with clinically positive lymph nodes.
Ghali F, Ryan S, Hansen M, Hayn M, Sammon J, Sarkar R, Murphy J, Kader A, Rose B. Prostatectomy in men with clinically positive lymph nodes. Journal Of Clinical Oncology 2019, 37: 327-327. DOI: 10.1200/jco.2019.37.7_suppl.327.Peer-Reviewed Original ResearchCox proportional hazards modelPositive lymph nodesBiopsy Gleason scoreProportional hazards modelProstate cancerLymph nodesPCa patientsGleason scoreHazards modelClinical positive lymph nodesHigh-risk prostate cancerNational Cancer DatabaseRisk prostate cancerPrimary treatment modalityPositive surgical marginsPathologic T stageDifficult clinical scenariosMedian followWorse OSNodal statusRisk patientsSystemic therapyClinical stagingSurgical marginsT stage