2022
Sense of mastery and attitude towards illness: Examining longitudinal benefits of a medical specialty camp for youth with sickle cell disease
Gillard A, Gagnon R, Pashankar F, Balsamo L, Grafft N, Miranda J, Boruchov D, Neri C, Sprinz P, Longyear C. Sense of mastery and attitude towards illness: Examining longitudinal benefits of a medical specialty camp for youth with sickle cell disease. Clinical Child Psychology And Psychiatry 2022, 28: 1012-1023. PMID: 36503316, DOI: 10.1177/13591045221145425.Peer-Reviewed Original Research
2021
Prevalence and risk factors of cognitive impairment in children with sickle cell disease in Egypt
Youssry I, ElGhamrawy M, Seif H, Balsamo L, Pashankar F, Mahrous M, Salama N. Prevalence and risk factors of cognitive impairment in children with sickle cell disease in Egypt. International Journal Of Hematology 2021, 115: 399-405. PMID: 34792734, DOI: 10.1007/s12185-021-03260-1.Peer-Reviewed Original ResearchConceptsSickle cell diseaseHigh lactate dehydrogenaseCell diseaseCognitive impairmentRisk factorsLactate dehydrogenaseCairo University Children's HospitalOlder ageSickle cell disease patientsUniversity Children's HospitalPossible risk factorsMagnetic resonance angiographyMagnetic resonance imagingHydroxyurea therapyTranscranial DopplerChildren's HospitalDisease patientsUnivariate analysisEarly initiationPatientsResonance angiographyImpaired cognitionResonance imagingIntelligence quotient (IQ) testDisease
2020
Emotion regulation, pain interference and affective symptoms in children and adolescents with sickle cell disease
Miller M, Balsamo L, Pashankar F, Bailey CS. Emotion regulation, pain interference and affective symptoms in children and adolescents with sickle cell disease. Journal Of Affective Disorders 2020, 282: 829-835. PMID: 33601724, DOI: 10.1016/j.jad.2020.12.068.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAffective SymptomsAnemia, Sickle CellChildDepressionEmotional RegulationFemaleHumansMalePainSurveys and QuestionnairesYoung AdultConceptsEmotion regulation strategiesEmotion Regulation QuestionnaireCognitive Emotion Regulation QuestionnaireMaladaptive emotion regulation strategiesSelf-report measuresSymptoms of depressionRegulation strategiesEmotion regulationYouth self-report measuresPain interferenceParticipants ages 8Symptoms of anxietyExperience of painPsychological functioningOutcomes Measurement Information SystemAge 8Measurement Information SystemAnxietyAffective symptomsYouthDepressionAffective disordersPediatric sickle cell clinicParticipantsMultiple regression model
2015
Impact of red blood cell alloimmunization on sickle cell disease mortality: a case series
Nickel RS, Hendrickson JE, Fasano RM, Meyer EK, Winkler AM, Yee MM, Lane PA, Jones YA, Pashankar FD, New T, Josephson CD, Stowell SR. Impact of red blood cell alloimmunization on sickle cell disease mortality: a case series. Transfusion 2015, 56: 107-114. PMID: 26509333, DOI: 10.1111/trf.13379.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnemia, Sickle CellBiomarkersErythrocyte TransfusionErythrocytesFemaleHumansIsoantibodiesMaleTransfusion ReactionYoung AdultConceptsHemolytic transfusion reactionsRBC alloimmunizationTransfusion supportAlloimmunized patientsSerious hemolytic transfusion reactionsSickle cell disease careRed blood cell transfusionRed blood cell alloimmunizationCompatible RBC unitsBlood cell transfusionRBC transfusion supportDirect clinical consequencesNonalloimmunized patientsCell transfusionClinical courseRBC transfusionWorse survivalCase seriesDisease careDisease mortalityImmunologic differencesTransfusion reactionsClinical impactClinical consequencesCompatible bloodHydroxyurea Improves Oxygen Saturation in Children With Sickle Cell Disease
Pashankar FD, Manwani D, Lee MT, Green NS. Hydroxyurea Improves Oxygen Saturation in Children With Sickle Cell Disease. Journal Of Pediatric Hematology/Oncology 2015, 37: 242-243. PMID: 25222060, PMCID: PMC4362807, DOI: 10.1097/mph.0000000000000251.Peer-Reviewed Original Research
2013
Weight Status of Children With Sickle Cell Disease
Chawla A, Sprinz PG, Welch J, Heeney M, Usmani N, Pashankar F, Kavanagh P. Weight Status of Children With Sickle Cell Disease. Pediatrics 2013, 131: e1168-e1173. PMID: 23460681, DOI: 10.1542/peds.2012-2225.Peer-Reviewed Original ResearchConceptsSickle cell diseaseBaseline Hb levelsHb levelsBMI percentileWeight statusCell diseaseHigher baseline Hb levelsSCD-related complicationsRetrospective chart reviewObesity-related conditionsOverweight/obesityRecent clinic visitYears of ageCalendar year 2007Select comorbiditiesChart reviewClinic visitsDL increaseElevated BMIHemoglobin levelsObese statusSickle genotypeUnderweight individualsHb SSDemographic informationCandidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea
Green NS, Ender KL, Pashankar F, Driscoll C, Giardina PJ, Mullen CA, Clark LN, Manwani D, Crotty J, Kisselev S, Neville KA, Hoppe C, Barral S. Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea. PLOS ONE 2013, 8: e55709. PMID: 23409025, PMCID: PMC3567082, DOI: 10.1371/journal.pone.0055709.Peer-Reviewed Original ResearchConceptsSickle cell diseaseFetal hemoglobin levelsHemoglobin levelsCell diseaseFetal hemoglobinBaseline levelsAdult sickle cell diseasePediatric sickle cell diseaseSubset of childrenPharmacologic therapyHydroxyurea therapyClinical severityPediatric diseasesInduced levelsSignificant associationTherapeutic inductionCandidate single nucleotide polymorphismsDiseaseSingle nucleotide polymorphismsHemoglobinSequence variantsChildrenTherapyBaselineHydroxyurea
2012
Massive splenic infarction in an adolescent with hemoglobin S‐HPFH
Whyte D, Forget B, Chui DH, Luo H, Pashankar F. Massive splenic infarction in an adolescent with hemoglobin S‐HPFH. Pediatric Blood & Cancer 2012, 60: e49-e51. PMID: 23281181, DOI: 10.1002/pbc.24444.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnemia, Sickle CellFetal HemoglobinHemoglobin, SickleHumansMaleSplenic InfarctionConceptsMassive splenic infarctVaso-occlusive crisisBenign clinical courseMassive splenic infarctionHistory of anemiaSickle cell anemiaClinical courseClinical suspicionSevere complicationsSplenic infarctSplenic infarctionHb S mutationCell anemiaAnemiaCompound heterozygosityFetal hemoglobinComplicationsPatientsS mutationsLittle evidenceHigh levelsInfarctionInfarctsHospitalSuspicionParental and other factors associated with hydroxyurea use for pediatric sickle cell disease
Oyeku SO, Driscoll MC, Cohen HW, Trachtman R, Pashankar F, Mullen C, Giardina PJ, Velazco N, Racine AD, Green NS. Parental and other factors associated with hydroxyurea use for pediatric sickle cell disease. Pediatric Blood & Cancer 2012, 60: 653-658. PMID: 23129068, PMCID: PMC3625668, DOI: 10.1002/pbc.24381.Peer-Reviewed Original ResearchConceptsSickle cell diseaseHU useCell diseaseHematology providersBivariate analysisPediatric sickle cell diseaseBenefits of hydroxyureaMajor therapeutic effectMultivariate logistic regressionLong-term safetyPotential side effectsParental knowledgeBetter parental knowledgeHU usersHydroxyurea useInter-institutional variabilityParents of childrenChildren ages 5Label useSickle genotypeTherapeutic effectClinical careEffective treatmentSide effectsClinical practice
2007
Sickle cell disease complicated by post‐streptococcal glomerulonephritis, cerebral hemorrhage and reversible posterior leucoencephalopathy syndrome
Pashankar FD, Ment LR, Pearson HA. Sickle cell disease complicated by post‐streptococcal glomerulonephritis, cerebral hemorrhage and reversible posterior leucoencephalopathy syndrome. Pediatric Blood & Cancer 2007, 50: 864-866. PMID: 17973321, DOI: 10.1002/pbc.21321.Peer-Reviewed Original ResearchConceptsReversible posterior leucoencephalopathy syndromeAcute post-streptococcal glomerulonephritisPost-streptococcal glomerulonephritisSickle cell diseaseCell diseaseHomozygous hemoglobin SS diseaseCentral nervous system eventsHemoglobin SS diseasePrimary cerebral infarctionNervous system eventsSickle cell nephropathyReversible causesCerebral infarctionCerebral hemorrhageIntracerebral hemorrhageSS diseaseHemorrhageDiseaseGlomerulonephritisPatientsPrognosisSyndromeHypertensionNephropathyComplications