2022
Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial
Srihari VH, Ferrara M, Li F, Kline E, Gülöksüz S, Pollard JM, Cahill JD, Mathis WS, Sykes L, Walsh BC, McDermott G, Seidman LJ, Gueorguieva R, Woods SW, Tek C, Keshavan MS. Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial. Schizophrenia Bulletin Open 2022, 3: sgab057. PMID: 35295656, PMCID: PMC8919192, DOI: 10.1093/schizbullopen/sgab057.Peer-Reviewed Original ResearchUntreated psychosisUS communitiesEarly detection campaignsFirst-episode servicesEffectiveness of careNumber of referralsQuasi-experimental trialEarly detection effortsOutcome measuresPsychosis onsetSecond quartileRapid enrollmentThird quartileQuartilePrEPDUPDetection campaignsDetection effortsReferralPsychosisU.S. communitiesTrialsAMPFESDuration
2014
Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study
Srihari VH, Tek C, Pollard J, Zimmet S, Keat J, Cahill JD, Kucukgoncu S, Walsh BC, Li F, Gueorguieva R, Levine N, Mesholam-Gately RI, Friedman-Yakoobian M, Seidman LJ, Keshavan MS, McGlashan TH, Woods SW. Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study. BMC Psychiatry 2014, 14: 335. PMID: 25471062, PMCID: PMC4262386, DOI: 10.1186/s12888-014-0335-3.Peer-Reviewed Original ResearchConceptsEarly detectionEarly outcomesGeographic catchmentTIPS studyYounger patientsAppropriate patientsUntreated psychosisPsychosis onsetEffective treatmentCare providersPsychotic symptomsPublic education campaignsPsychotic disordersHelp-seeking behaviorSecondary aimComprehensive interventionPatientsIntervention servicesDUPEducation campaignsOutcomesSocial marketing approachPrimary aimTreatmentFES