2013
Electrophysiological Remodeling in Heart Failure
Akar F, Tomaselli G. Electrophysiological Remodeling in Heart Failure. 2013, 369-386. DOI: 10.1007/978-1-4471-4881-4_22.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHeart failureTreatment of arrhythmiasCellular electrophysiological propertiesIon channelsSafe therapyConduction abnormalitiesElectrophysiological remodelingSudden deathNovel pharmacologicalArrhythmogenic triggersElectrophysiological propertiesAction potentialsArrhythmiasFunctional consequencesIonic mechanismsMolecular mechanismsOrgan levelFailureTherapyAbnormalitiesPharmacologicalRepolarization
2004
Ionic mechanisms of cardiac arrhythmias
Akar F, Tomaselli G. Ionic mechanisms of cardiac arrhythmias. Drug Discovery Today Disease Mechanisms 2004, 1: 23-30. DOI: 10.1016/j.ddmec.2004.08.005.ChaptersIndividual cardiac myocytesArrhythmia controlCardiac arrhythmiasIntricate vascular networkDuke University Medical CenterCardiac myocytesGood arrhythmia controlSudden cardiac death casesCardiac death casesUniversity Medical CenterIonic mechanismsGenetic risk factorsPascal J. Goldschmidt-ClermontGlobal electrical activityCardiovascular deathAbnormal heart rhythmMalignant arrhythmiasDrug therapyRhythm disturbancesHeart diseaseRisk factorsMedical CenterTherapeutic strategiesArrhythmia syndromesCardiac chambers