2020
Dosimetric and Radiobiological Comparison of Five Techniques for Postmastectomy Radiotherapy with Simultaneous Integrated Boost
Tang D, Liang Z, Guan F, Yang Z. Dosimetric and Radiobiological Comparison of Five Techniques for Postmastectomy Radiotherapy with Simultaneous Integrated Boost. BioMed Research International 2020, 2020: 9097352. PMID: 32775448, PMCID: PMC7391102, DOI: 10.1155/2020/9097352.Peer-Reviewed Original ResearchConceptsNormal tissue complication probabilitySimultaneous integrated boostHighest normal-tissue complication probabilityPostmastectomy radiotherapyIntegrated boostLeft-sided breast cancer treatmentComplication probabilityHybrid intensity-modulated radiotherapyLeft-sided breast cancerSimilar dosimetric resultsSuperior dose sparingBetter dose coverageBetter conformity indexBreast cancer treatmentIntensity-modulated radiotherapyOAR mean doseContralateral breastMean doseTD plansBreast cancerConformity indexRadiobiological comparisonDose sparingDose coverageClinical practice
2019
A Monte Carlo study of pinhole collimated Cerenkov luminescence imaging integrated with radionuclide treatment
Geng C, Ai Y, Tang X, Shu D, Gong C, Guan F. A Monte Carlo study of pinhole collimated Cerenkov luminescence imaging integrated with radionuclide treatment. Physical And Engineering Sciences In Medicine 2019, 42: 481-487. PMID: 30830649, DOI: 10.1007/s13246-019-00744-7.Peer-Reviewed Original Research
2018
Patterns of Local-Regional Failure After Intensity Modulated Radiation Therapy or Passive Scattering Proton Therapy With Concurrent Chemotherapy for Non-Small Cell Lung Cancer
Yang P, Xu T, Gomez DR, Deng W, Wei X, Elhalawani H, Jin H, Guan F, Mirkovic D, Xu Y, Mohan R, Liao Z. Patterns of Local-Regional Failure After Intensity Modulated Radiation Therapy or Passive Scattering Proton Therapy With Concurrent Chemotherapy for Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2018, 103: 123-131. PMID: 30165127, DOI: 10.1016/j.ijrobp.2018.08.031.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerInternal target volumePlanning target volumeCell lung cancerLarge tumorsRegional failureMarginal failureLocal failureLung cancerSmall tumorsCox proportional hazards analysisTarget volumeLocal-regional failureOnly independent predictorOverall survival rateProportional hazards analysisProton therapyComputed tomography simulationPassive Scattering Proton TherapyConcurrent chemotherapyLocoregional failureFavorable survivalIndependent predictorsTumor controlTomography scan
2015
Calculations of S values and effective dose for the radioiodine carrier and surrounding individuals based on Chinese hybrid reference phantoms using the Monte Carlo technique
Geng C, Tang X, Qian W, Guan F, Johns J, Yu H, Gong C, Shu D, Chen D. Calculations of S values and effective dose for the radioiodine carrier and surrounding individuals based on Chinese hybrid reference phantoms using the Monte Carlo technique. Journal Of Radiological Protection 2015, 35: 707-717. PMID: 26344387, DOI: 10.1088/0952-4746/35/3/707.Peer-Reviewed Original ResearchChemoradiation therapy using cyclopamine-loaded liquid–lipid nanoparticles and lutetium-177-labeled core-crosslinked polymeric micelles
You J, Zhao J, Wen X, Wu C, Huang Q, Guan F, Wu R, Liang D, Li C. Chemoradiation therapy using cyclopamine-loaded liquid–lipid nanoparticles and lutetium-177-labeled core-crosslinked polymeric micelles. Journal Of Controlled Release 2015, 202: 40-48. PMID: 25637565, PMCID: PMC4394992, DOI: 10.1016/j.jconrel.2015.01.031.Peer-Reviewed Original ResearchConceptsCombination therapyHigher antitumor cytotoxicityMurine breast cancerMouse xenograft modelCell linesDesirable pharmacokinetic propertiesChemoradiation therapyTumor sizeTumor responseMouse survivalPancreatic cancerAntitumor cytotoxicitySystemic administrationBreast cancerIntravenous injectionPreclinical studiesTumor relapseRadiation therapyXenograft modelIntratumoral injectionAdenocarcinoma modelTumor growthLower clonogenicityCell responsesTherapy