2020
Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns
Ma D, Bronk L, Kerr M, Sobieski M, Chen M, Geng C, Yiu J, Wang X, Sahoo N, Cao W, Zhang X, Stephan C, Mohan R, Grosshans DR, Guan F. Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns. Scientific Reports 2020, 10: 3199. PMID: 32081928, PMCID: PMC7035246, DOI: 10.1038/s41598-020-60246-5.Peer-Reviewed Original ResearchConceptsIntensity-modulated proton therapyLow-energy beamsIntensity modulation patternCurrent treatment planProton therapyBiological effectsDelivery strategiesTarget doseTherapeutic indexTreatment planHigh-energy beamsEffective doseEnhanced biological effectClinical potentialTherapyCancer cellsDoseBragg peak
2013
TH‐F‐105‐03: Experimental Design and Preliminary Results for High‐Resolution and High‐Throughput In‐Vitro Measurements of Proton RBE
Guan F, Mohan R, Dinh J, Kerr M, Perles L, Mirkovic D, Titt U, Zhu X, Gillin M, Meyn R, Lin S, Grosshans D. TH‐F‐105‐03: Experimental Design and Preliminary Results for High‐Resolution and High‐Throughput In‐Vitro Measurements of Proton RBE. Medical Physics 2013, 40: 552-552. DOI: 10.1118/1.4815816.Peer-Reviewed Original Research