2023
Alterations in microRNA of extracellular vesicles associated with major depression, attention-deficit/hyperactivity and anxiety disorders in adolescents
Honorato-Mauer J, Xavier G, Ota V, Chehimi S, Mafra F, Cuóco C, Ito L, Ormond R, Asprino P, Oliveira A, Bugiga A, Torrecilhas A, Bressan R, Manfro G, Miguel E, Rohde L, Pan P, Salum G, Pellegrino R, Belangero S, Santoro M. Alterations in microRNA of extracellular vesicles associated with major depression, attention-deficit/hyperactivity and anxiety disorders in adolescents. Translational Psychiatry 2023, 13: 47. PMID: 36746925, PMCID: PMC9902559, DOI: 10.1038/s41398-023-02326-4.Peer-Reviewed Original ResearchConceptsMental health disordersCross-sectional analysisMajor depressive disorderAttention-deficit/hyperactivity disorderHealth disordersAnxiety disordersExtracellular vesiclesLarge ongoing cohort studiesMiR-432-5pPeripheral extracellular vesiclesTime pointsOngoing cohort studyMiR-328-3pSerum extracellular vesiclesLongitudinal analysisWave 2Deficit/hyperactivity disorderAdolescent participantsTotal extracellular vesiclesAttention-deficit/hyperactivityMiRNA expressionCohort studyDepressive disorderMajor depressionMiR-584-5p
2012
Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study
Torres A, Fontenelle L, Ferrão Y, do Rosário M, Torresan R, Miguel E, Shavitt R. Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study. Journal Of Psychiatric Research 2012, 46: 724-732. PMID: 22464941, DOI: 10.1016/j.jpsychires.2012.03.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresOCD patientsLogistic regressionDSM-IV OCD patientsCertain clinical featuresCross-sectional studyAttention-deficit/hyperactivity disorderStatistical univariate analysisBrazilian Research ConsortiumDeficit/hyperactivity disorderHigher anxiety scoresYale-Brown ObsessiveSymptom onsetInsidious onsetMulticenter studyObsessive-compulsive spectrum disordersSectional studyPossible confoundersUnivariate analysisTic disordersHoarding dimensionPatientsSymptomsPoor insight