Clinical Utility of Rapid Clonidine‐naltrcxone Detoxification for Opioid Abusers
VINING E, KOSTEN T, KLEBER H. Clinical Utility of Rapid Clonidine‐naltrcxone Detoxification for Opioid Abusers. Addiction 1988, 83: 567-575. PMID: 3382815, DOI: 10.1111/j.1360-0443.1988.tb02576.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultClinical ProtocolsClonidineDrug Therapy, CombinationFemaleHeroinHumansMaleNaltrexoneSubstance-Related DisordersConceptsNaltrexone therapyAbrupt opioid withdrawalSingle morning dosesEffects of naltrexoneNaloxone challenge testMorning dosesOpioid withdrawalBlood pressureOpioid dependenceSingle doseMean doseNaltrexone dosesOpioid abusersClinical utilityEffective treatmentClinical problemClonidine hydrochlorideDay 1Heroin usersDay 2Challenge testHydrochloride treatmentNaltrexone hydrochlorideThird dayFirst day