2007
A Critical Appraisal of “Chronic Lyme Disease”
Feder HM, Johnson BJ, O'Connell S, Shapiro ED, Steere AC, Wormser GP, Agger W, Artsob H, Auwaerter P, Dumler J, Bakken J, Bockenstedt L, Green J, Dattwyler R, Munoz J, Nadelman R, Schwartz I, Draper T, McSweegan E, Halperin J, Klempner M, Krause P, Mead P, Morshed M, Porwancher R, Radolf J, Smith R, Sood S, Weinstein A, Wong S, Zemel L. A Critical Appraisal of “Chronic Lyme Disease”. New England Journal Of Medicine 2007, 357: 1422-1430. PMID: 17914043, DOI: 10.1056/nejmra072023.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, BacterialBorrelia burgdorferi GroupChronic DiseaseControlled Clinical Trials as TopicDiagnosis, DifferentialHumansLyme DiseasePatient SelectionConceptsAcute Lyme diseaseChronic Lyme diseaseLyme diseasePersistent painNeurocognitive symptomsCommon tick-borne infectionSerious public health problemPublic health problemTick-borne infectionsBorrelia burgdorferi sensu strictoBurgdorferi sensu strictoHealth problemsDiseasePainPatientsSymptomsFatigueInfectionDiagnosis
2000
Lyme Disease
Shapiro E, Gerber M. Lyme Disease. Clinical Infectious Diseases 2000, 31: 533-542. PMID: 10987718, DOI: 10.1086/313982.Peer-Reviewed Original ResearchConceptsLyme diseaseCommon vector borne diseaseSeventh cranial nerve palsyOnly nonspecific symptomsCranial nerve palsyAnnular rashNerve palsyNonspecific symptomsAseptic meningitisSymptomatic infectionFrequent manifestationCommon causeActual morbidityPossible diagnosisSerological testsMost personsDiseaseBorrelia burgdorferiSymptomsVector borne diseasesBorne diseasesFrequent useManifestationsUnited StatesCausePractice Guidelines for the Treatment of Lyme Disease
Wormser G, Nadelman R, Dattwyler R, Dennis D, Shapiro E, Steere A, Rush T, Rahn D, Coyle P, Persing D, Fish D, Luft B. Practice Guidelines for the Treatment of Lyme Disease. Clinical Infectious Diseases 2000, 31: s1-s14. PMID: 10982743, DOI: 10.1086/314053.Peer-Reviewed Original ResearchAnimalsArachnid VectorsBites and StingsBorrelia burgdorferi GroupHumansIxodesLyme DiseaseTime Factors
1996
Lyme Disease in Children in Southeastern Connecticut
Gerber M, Shapiro E, Burke G, Parcells V, Bell G. Lyme Disease in Children in Southeastern Connecticut. New England Journal Of Medicine 1996, 335: 1270-1274. PMID: 8857006, DOI: 10.1056/nejm199610243351703.Peer-Reviewed Original ResearchConceptsErythema migrans lesionsSingle erythema migrans lesionLyme diseaseErythema migransClinical manifestationsMultiple erythema migrans lesionsCommunity-based cohort studyFacial nerve palsyInitial clinical manifestationPrompt clinical responseEarly Lyme diseasePercent of childrenConventional antimicrobial therapyMultiple erythemaClinical responseCohort studyAseptic meningitisConsecutive patientsMedian ageProspective dataAntimicrobial therapyAntibody testNew episodesPatientsLesions