2006
The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America
Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Krause PJ, Bakken JS, Strle F, Stanek G, Bockenstedt L, Fish D, Dumler JS, Nadelman RB. The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America. Clinical Infectious Diseases 2006, 43: 1089-1134. PMID: 17029130, DOI: 10.1086/508667.Peer-Reviewed Original ResearchConceptsInfectious Diseases SocietyHuman granulocytic anaplasmosisDiseases SocietyLyme diseasePost-Lyme disease syndromeGranulocytic anaplasmosisPrevious treatment guidelinesManagement of patientsClinical practice guidelinesEvidence-based guidelinesHealth care providersTickborne infectionTreatment guidelinesClinical manifestationsAntimicrobial therapyClinical assessmentPractice guidelinesCare providersDisease syndromeExpert panelDiseasePreventionPatientsTherapyInfection
1996
Lyme Disease in Children in Southeastern Connecticut
Gerber M, Shapiro E, Burke G, Parcells V, Bell G. Lyme Disease in Children in Southeastern Connecticut. New England Journal Of Medicine 1996, 335: 1270-1274. PMID: 8857006, DOI: 10.1056/nejm199610243351703.Peer-Reviewed Original ResearchConceptsErythema migrans lesionsSingle erythema migrans lesionLyme diseaseErythema migransClinical manifestationsMultiple erythema migrans lesionsCommunity-based cohort studyFacial nerve palsyInitial clinical manifestationPrompt clinical responseEarly Lyme diseasePercent of childrenConventional antimicrobial therapyMultiple erythemaClinical responseCohort studyAseptic meningitisConsecutive patientsMedian ageProspective dataAntimicrobial therapyAntibody testNew episodesPatientsLesions
1994
Lyme Disease
Baltimore R, Shapiro E. Lyme Disease. Pediatrics In Review 1994, 15: 167-173. PMID: 8036192, DOI: 10.1542/pir.15-5-167.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLyme diseaseLyme borreliosisCommon vector-borne diseaseIxodes ticksNymphal Ixodes ticksUnexplained arthritisLyme arthritisClinical manifestationsBacterial etiologyClusters of childrenBorrelia burgdoferiMedical attentionSystemic infectionArthritisDistinct entityDiseaseBorrelia burgdorferiPencil pointVector-borne diseasesBorreliosisTicksWood tickPatientsEtiologyYearsLyme Disease
Baltimore R, Shapiro E. Lyme Disease. Pediatrics In Review 1994, 15: 167-173. DOI: 10.1542/pir.15.5.167.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLyme diseaseLyme borreliosisCommon vector-borne diseaseIxodes ticksNymphal Ixodes ticksUnexplained arthritisLyme arthritisClinical manifestationsBacterial etiologyClusters of childrenBorrelia burgdoferiMedical attentionSystemic infectionArthritisDistinct entityDiseaseBorrelia burgdorferiPencil pointVector-borne diseasesBorreliosisTicksWood tickPatientsEtiologyYears
1992
A Controlled Trial of Antimicrobial Prophylaxis for Lyme Disease after Deer-Tick Bites
Shapiro E, Gerber M, Holabird N, Berg A, Feder H, Bell G, Rys P, Persing D. A Controlled Trial of Antimicrobial Prophylaxis for Lyme Disease after Deer-Tick Bites. New England Journal Of Medicine 1992, 327: 1769-1773. PMID: 1435930, DOI: 10.1056/nejm199212173272501.Peer-Reviewed Original ResearchConceptsDeer tick biteRisk of infectionProphylactic antimicrobial treatmentLyme diseaseB. burgdorferiAntimicrobial treatmentDeer ticksPlacebo-controlled trialPlacebo-treated subjectsCare of personsAsymptomatic seroconversionAntimicrobial prophylaxisErythema migransClinical manifestationsPolymerase chain reactionLate manifestationPlaceboDiseaseSerum samplesInfectionBorrelia burgdorferiBiteChain reactionAmoxicillinBurgdorferi