Case fatality risk of diarrhoeal pathogens: a systematic review and meta-analysis
Asare EO, Hergott D, Seiler J, Morgan B, Archer H, Wiyeh AB, Guo B, Driver M, Giersing B, Hasso-Agopsowicz M, Lingappa J, Lopman BA, Pitzer VE. Case fatality risk of diarrhoeal pathogens: a systematic review and meta-analysis. International Journal Of Epidemiology 2022, 51: 1469-1480. PMID: 35578827, PMCID: PMC9557849, DOI: 10.1093/ije/dyac098.Peer-Reviewed Original ResearchConceptsCase fatality riskDiarrhoeal pathogensEnteropathogenic Escherichia coliSystematic reviewMultilevel mixed-effects logistic regression modelsMixed-effects logistic regression modelLower odds ratioOverall case fatality riskRandom-effects modelLogistic regression modelsDiarrhoea mortalityPrimary outcomeFatality riskOdds ratioMortality rateVaccine developmentAge groupsEnteric pathogensPotential predictorsBurden modelMore studiesReview criteriaConsiderable heterogeneityDifferent pathogensCFR estimates