2022
Coronavirus disease 2019 and the young heart: prevention, treatment, and return to play
Beach CM, Faherty E, Pesce M. Coronavirus disease 2019 and the young heart: prevention, treatment, and return to play. Current Opinion In Pediatrics 2022, 34: 471-475. PMID: 36036422, PMCID: PMC9593324, DOI: 10.1097/mop.0000000000001167.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdolescentChildCOVID-19COVID-19 VaccinesHumansPandemicsReturn to SportSystemic Inflammatory Response SyndromeConceptsCOVID-19 vaccinationRisk factorsSevere diseasePhysical activitySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissionAcute COVID-19 infectionAcute COVID-19Regular physical activityViral prevalenceCOVID-19 infectionSpecific risk factorsCoronavirus disease 2019Current care modelsPrevention of diseaseInflammatory syndromeCardiac manifestationsPoor outcomeDisease 2019Care modelYoung heartsViral transmissionInfectionDiseaseCOVID-19VaccinationLongitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C)
He M, Leone DM, Frye R, Ferdman DJ, Shabanova V, Kosiv KA, Sugeng L, Faherty E, Karnik R. Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C). Pediatric Cardiology 2022, 43: 844-854. PMID: 34993558, PMCID: PMC8739007, DOI: 10.1007/s00246-021-02796-7.Peer-Reviewed Original ResearchMeSH KeywordsChildCOVID-19HumansLongitudinal StudiesReproducibility of ResultsRetrospective StudiesSystemic Inflammatory Response SyndromeVentricular Dysfunction, LeftVentricular Function, LeftConceptsMIS-C patientsAcute phaseChronic phaseInflammatory syndromeTwo-dimensional speckle tracking echocardiographySubclinical myocardial injuryCircumferential strainMultisystem inflammatory syndromeLeft ventricular dysfunctionSingle-institution reviewSpeckle tracking echocardiographyTwo-dimensional echocardiographyCoronavirus disease 2019Future adverse eventsVentricular function parametersBasal anterolateral segmentMean GCSVentricular dysfunctionAdverse eventsFractional shorteningSignificant sequelaeVentricular strainMyocardial dysfunctionGlobal longitudinalMyocardial injury
2021
Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination
Marshall M, Ferguson ID, Lewis P, Jaggi P, Gagliardo C, Collins JS, Shaughnessy R, Caron R, Fuss C, Corbin KJE, Emuren L, Faherty E, Hall EK, Di Pentima C, Oster ME, Paintsil E, Siddiqui S, Timchak DM, Guzman-Cottrill JA. Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination. Pediatrics 2021, 148: e2021052478. PMID: 34088762, DOI: 10.1542/peds.2021-052478.Peer-Reviewed Original ResearchConceptsPfizer-BioNTech COVID-19 vaccinationCOVID-19 vaccinationAcute myocarditisClinical courseLate gadolinium enhancement (LGE) characteristicsPolymerase chain reaction test resultsTranscription polymerase chain reaction (RT-PCR) test resultsVaccine Adverse Event Reporting SystemCoronavirus disease 2019 (COVID-19) vaccinationAcute COVID-19Multisystem inflammatory syndromeAdverse Event Reporting SystemImportant adverse eventsTime of presentationNonsteroidal antiinflammatory drugsHealthy male adolescentsGadolinium enhancement characteristicsEvent Reporting SystemReaction test resultsChest painElevated troponinInflammatory syndromeIntravenous immunoglobulinAdverse eventsSecond dose