2023
Twist response of actin filaments
Bibeau J, Pandit N, Gray S, Nejad N, Sindelar C, Cao W, De La Cruz E. Twist response of actin filaments. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2208536120. PMID: 36656858, PMCID: PMC9942836, DOI: 10.1073/pnas.2208536120.Peer-Reviewed Original Research
2019
Active cargo positioning in antiparallel transport networks
Richard M, Blanch-Mercader C, Ennomani H, Cao W, De La Cruz EM, Joanny JF, Jülicher F, Blanchoin L, Martin P. Active cargo positioning in antiparallel transport networks. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 14835-14842. PMID: 31289230, PMCID: PMC6660773, DOI: 10.1073/pnas.1900416116.Peer-Reviewed Original Research
2016
Architecture and Connectivity Govern Actin Network Contractility
Ennomani H, Letort G, Guérin C, Martiel JL, Cao W, Nédélec F, De La Cruz EM, Théry M, Blanchoin L. Architecture and Connectivity Govern Actin Network Contractility. Current Biology 2016, 26: 616-626. PMID: 26898468, PMCID: PMC4959279, DOI: 10.1016/j.cub.2015.12.069.Peer-Reviewed Original Research
2013
Competitive displacement of cofilin can promote actin filament severing
Elam WA, Kang H, De La Cruz EM. Competitive displacement of cofilin can promote actin filament severing. Biochemical And Biophysical Research Communications 2013, 438: 728-731. PMID: 23911787, PMCID: PMC3785092, DOI: 10.1016/j.bbrc.2013.07.109.Peer-Reviewed Original Research
2009
Myosin Isoform Determines the Conformational Dynamics and Cooperativity of Actin Filaments in the Strongly Bound Actomyosin Complex
Prochniewicz E, Chin HF, Henn A, Hannemann DE, Olivares AO, Thomas DD, De La Cruz EM. Myosin Isoform Determines the Conformational Dynamics and Cooperativity of Actin Filaments in the Strongly Bound Actomyosin Complex. Journal Of Molecular Biology 2009, 396: 501-509. PMID: 19962990, PMCID: PMC2834967, DOI: 10.1016/j.jmb.2009.11.063.Peer-Reviewed Original ResearchChapter 6 Kinetic and Equilibrium Analysis of the Myosin ATPase
De La Cruz EM, Ostap EM. Chapter 6 Kinetic and Equilibrium Analysis of the Myosin ATPase. Methods In Enzymology 2009, 455: 157-192. PMID: 19289206, PMCID: PMC2921708, DOI: 10.1016/s0076-6879(08)04206-7.Peer-Reviewed Original Research
2005
Vertebrate Myosin VIIb Is a High Duty Ratio Motor Adapted for Generating and Maintaining Tension*
Henn A, De La Cruz EM. Vertebrate Myosin VIIb Is a High Duty Ratio Motor Adapted for Generating and Maintaining Tension*. Journal Of Biological Chemistry 2005, 280: 39665-39676. PMID: 16186105, DOI: 10.1074/jbc.m507667200.Peer-Reviewed Original ResearchConceptsClass VII myosinMyosin VIIbActin filament concentrationUnique cellular functionsInner ear hair cellsCatalytic motor domainEar hair cellsActin filament bundlesNon-muscle myosinSteady-state ATPase activityActin cytoskeletonHigh conservationCellular functionsMyosin VIIa functionCDNA libraryActin bindingDeafness phenotypeMembrane surface receptorsATPase cycleEnzymatic propertiesSurface receptorsFilament bundlesIntestinal brush borderMolecular motorsQuantitative equilibrium
2004
Relating biochemistry and function in the myosin superfamily
De La Cruz EM, Ostap EM. Relating biochemistry and function in the myosin superfamily. Current Opinion In Cell Biology 2004, 16: 61-67. PMID: 15037306, DOI: 10.1016/j.ceb.2003.11.011.Peer-Reviewed Original Research
2002
Kinetic Characterization of the Weak Binding States of Myosin V †
Yengo CM, De La Cruz EM, Safer D, Ostap EM, Sweeney HL. Kinetic Characterization of the Weak Binding States of Myosin V †. Biochemistry 2002, 41: 8508-8517. PMID: 12081502, DOI: 10.1021/bi015969u.Peer-Reviewed Original Research
2000
Actin and Light Chain Isoform Dependence of Myosin V Kinetics †
De La Cruz E, Wells A, Sweeney H, Ostap E. Actin and Light Chain Isoform Dependence of Myosin V Kinetics †. Biochemistry 2000, 39: 14196-14202. PMID: 11087368, DOI: 10.1021/bi001701b.Peer-Reviewed Original ResearchADP Inhibition of Myosin V ATPase Activity
De La Cruz E, Sweeney H, Ostap E. ADP Inhibition of Myosin V ATPase Activity. Biophysical Journal 2000, 79: 1524-1529. PMID: 10969013, PMCID: PMC1301045, DOI: 10.1016/s0006-3495(00)76403-4.Peer-Reviewed Original Research
1999
The kinetic mechanism of myosin V
De La Cruz E, Wells A, Rosenfeld S, Ostap E, Sweeney H. The kinetic mechanism of myosin V. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 13726-13731. PMID: 10570140, PMCID: PMC24132, DOI: 10.1073/pnas.96.24.13726.Peer-Reviewed Original Research