Enhanced Antitumor Immunity in Mice Deficient in CD69
Esplugues E, Sancho D, Vega-Ramos J, Martínez-A C, Syrbe U, Hamann A, Engel P, Sánchez-Madrid F, Lauzurica P. Enhanced Antitumor Immunity in Mice Deficient in CD69. Journal Of Experimental Medicine 2003, 197: 1093-1106. PMID: 12732655, PMCID: PMC2193974, DOI: 10.1084/jem.20021337.Peer-Reviewed Original ResearchConceptsAnti-tumor responseCD69-/- miceEnhanced anti-tumor responseWT miceMHC class I- tumorsT cell productionTGF-beta productionChemokine MCP-1Wild-type miceTGF-beta regulationLocal lymphocytesAntitumor immunityVivo blockadeNK cellsAntibody treatmentI tumorsMCP-1CD69 expressionLymphocyte apoptosisMice DeficientTherapy of tumorsTumor growthCD69MiceVivo role