2024
Contemporary Training in American Critical Care Cardiology: Minnesota Critical Care Cardiology Education Summit JACC Scientific Expert Panel
Elliott A, Bartos J, Barnett C, Miller P, Roswell R, Alviar C, Bennett C, Berg D, Bohula E, Chonde M, Dahiya G, Fleitman J, Gage A, Hansra B, Higgins A, Hollenberg S, Horowitz J, Jentzer J, Katz J, Karpenshif Y, Lee R, Menon V, Metkus T, Mukundan S, Rhinehart Z, Senman B, Senussi M, Solomon M, Vallabhajosyula S, Dudzinski D. Contemporary Training in American Critical Care Cardiology: Minnesota Critical Care Cardiology Education Summit JACC Scientific Expert Panel. Journal Of The American College Of Cardiology 2024, 84: 1436-1454. PMID: 39357941, DOI: 10.1016/j.jacc.2024.05.082.Peer-Reviewed Original ResearchEpidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions
Berg D, Bohula E, Patel S, Alfonso C, Alviar C, Baird-Zars V, Barnett C, Barsness G, Bennett C, Chaudhry S, Fordyce C, Ghafghazi S, Gidwani U, Goldfarb M, Katz J, Menon V, Miller P, Newby L, Papolos A, Park J, Pierce M, Proudfoot A, Sinha S, Sridharan L, Thompson A, van Diepen S, Morrow D. Epidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions. European Heart Journal Acute Cardiovascular Care 2024, 13: 709-714. PMID: 39208447, PMCID: PMC11518926, DOI: 10.1093/ehjacc/zuae098.Peer-Reviewed Original ResearchCardiac intensive care unitSecondary CSConsensus definitionConcomitant cardiac arrestCritical Care Cardiology Trials NetworkRelevant to clinical practiceAcademic Research ConsortiumIn-hospital mortalityResearch ConsortiumCardiogenic shockIntensive care unitMultinational research networksCardiac arrestClinical practiceEvidence of hypoperfusionCare unitTrials NetworkTIMI Study GroupContemporary registryRegistryShock criteriaCS classificationStudy groupEpidemiologyClinical trialsThe Why, The Who, and The How: Launching the Society of Critical Care Cardiology
Senman B, Dudzinski D, Gage A, Miller P, Katz J. The Why, The Who, and The How: Launching the Society of Critical Care Cardiology. Journal Of Shock And Hemodynamics 2024, 2 DOI: 10.58464/2836-0605.1060.Peer-Reviewed Original ResearchOutcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units
Shahu A, Namburar S, Banna S, Harris A, Schenck C, Trejo-Paredes C, Thomas A, Ali T, Carnicelli A, Barnett C, Solomon M, Miller P. Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units. JACC Advances 2024, 3: 101199. PMID: 39238851, PMCID: PMC11375252, DOI: 10.1016/j.jacadv.2024.101199.Peer-Reviewed Original ResearchAcute myocardial infarctionAssociated with lower in-hospital mortalityIn-hospital mortalityLower in-hospital mortalityIntensive care unitMedical ICUPrimary diagnosis of acute myocardial infarctionMultivariable adjustmentCICU admissionInvasive mechanical ventilationVizient Clinical Data BaseBackground Acute myocardial infarctionDiagnosis of acute myocardial infarctionMultivariate logistic regressionMedical intensive care unitClinical outcomesMechanical ventilationCardiogenic shockClinical Data BaseMyocardial infarctionHospital sizeTriage of critically ill patientsMedian ventilator daysTeaching hospitalLogistic regressionManagement of Post-cardiotomy Shock
Hall E, Papolos A, Miller P, Barnett C, Kenigsberg B. Management of Post-cardiotomy Shock. US Cardiology Review 2024, 18: e11. PMID: 39494414, PMCID: PMC11526484, DOI: 10.15420/usc.2024.16.Peer-Reviewed Original ResearchCurrent practices in the management of temporary mechanical circulatory support: A survey of CICU directors in North America
Balgobind A, Pierce M, Alviar C, Barnett C, Barsness G, Chaudhry S, Chonde M, Cooper H, Daniels L, Gidwani U, Fordyce C, Goldfarb M, Katz J, Kontos M, Kwon Y, Liebner E, Liu S, Miller P, Newby L, O'Brien C, Papolos A, Pisani B, Potter B, Proudfoot A, Roswell R, Sinha S, Smith T, Thompson A, van Diepen S, Zakaria S, Morrow D, Villela M. Current practices in the management of temporary mechanical circulatory support: A survey of CICU directors in North America. American Heart Journal 2024, 276: 115-119. PMID: 39182940, DOI: 10.1016/j.ahj.2024.05.018.Peer-Reviewed Original ResearchTemperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest
Beekman R, Kim N, Nguyen C, McGinniss G, Deng Y, Kitlen E, Garcia G, Wira C, Khosla A, Johnson J, Miller P, Perman S, Sheth K, Greer D, Gilmore E. Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest. Annals Of Emergency Medicine 2024, 84: 549-559. PMID: 39033449, DOI: 10.1016/j.annemergmed.2024.06.007.Peer-Reviewed Original ResearchOut-of-hospital cardiac arrestNeurological outcomeDevice cohortCardiac arrestOut-of-hospital cardiac arrest patientsConsecutive out-of-hospital cardiac arrestPreinduction timeInterquartile rangeAssociated with improved outcomesCardiac arrest patientsProportion of patientsMultivariate logistic regression modelInverse probability of treatmentDevice timeInverse probability treatment weightsProbability of treatmentProspective trialsOHCA patientsArrest patientsClinical outcomesLogistic regression modelsCenter studyEarly initiationSecondary outcomesTreatment weightingArterial hyperoxia and mortality in the cardiac intensive care unit
Jentzer J, van Diepen S, Alviar C, Miller P, Metkus T, Geller B, Kashani K. Arterial hyperoxia and mortality in the cardiac intensive care unit. Current Problems In Cardiology 2024, 49: 102738. PMID: 39025170, DOI: 10.1016/j.cpcardiol.2024.102738.Peer-Reviewed Original ResearchCardiac intensive care unitIn-hospital mortalityIntensive care unitEvaluate predictors of in-hospital mortalityArterial hyperoxiaPaO2 >Mayo Clinic CICU patientsAssociated with increased in-hospital mortalityCare unitPredictors of in-hospital mortalityAssociated with higher in-hospital mortalityAssociated with adverse outcomesTime of CICU admissionAdmission PaO2Higher in-hospital mortalityCritically ill populationArterial partial pressure of oxygenPositive-pressure ventilationJ-shaped associationExposure to hyperoxiaCICU patientsArterial partial pressureCICU admissionEvaluate predictorsMedian PaO2Exposure to hyperoxemia and mortality in cardiac intensive care unit patients
Alviar C, Jentzer J, Van Diepen S, Metkus T, Miller P, Kashani K. Exposure to hyperoxemia and mortality in cardiac intensive care unit patients. European Heart Journal Acute Cardiovascular Care 2024, 13: zuae036.138. DOI: 10.1093/ehjacc/zuae036.138.Peer-Reviewed Original ResearchIn-hospital mortalityCardiac intensive care unitCardiac intensive care unit admissionJ-shaped associationJ-shaped relationshipCritical care settingCardiac intensive care unit patientsCare settingsAssociated with increased in-hospital mortalityCare conditionsInpatient deathCharlson Comorbidity IndexMayo Clinic CICU patientsIntensive care unit patientsAssociated with adverse outcomesAdmission diagnosisLogistic regressionCICU patientsExposure to hyperoxemiaHigher mortalityPrimary outcomeIntensive care unitIll cardiac patientsGeneral critical care settingCardiac patientsTracheostomy in Patients with Acute Myocardial Infarction and Respiratory Failure
Grammatico M, Banna S, Shahu A, Gastanadui M, Jimenez J, Heck C, Arias-Olson A, Thomas A, Ali T, Miller P. Tracheostomy in Patients with Acute Myocardial Infarction and Respiratory Failure. Journal Of Intensive Care Medicine 2024, 39: 1131-1137. PMID: 38715423, DOI: 10.1177/08850666241253202.Peer-Reviewed Original ResearchDays of tracheostomyInvasive mechanical ventilationIn-hospital mortalityAcute myocardial infarctionTiming of tracheostomyRespiratory failureAntiplatelet regimensMyocardial infarctionAssociated with lower in-hospital mortalityIncidence of tracheostomyLower in-hospital mortalityProportion of patientsIncidence of patientsDiagnosis of acute myocardial infarctionDAPT interruptionTracheostomy complicationsBlood transfusionOpen tracheostomyAntiplatelet therapyMechanical ventilationMultivariable adjustmentDAPT usePrimary diagnosis of acute myocardial infarctionClinical Data BaseTracheostomyComplex Heart–Lung Ventilator Emergencies in the CICU
Lopez M, Applefeld W, Miller P, Elliott A, Bennett C, Lee B, Barnett C, Solomon M, Corradi F, Sionis A, Mireles-Cabodevila E, Tavazzi G, Alviar C. Complex Heart–Lung Ventilator Emergencies in the CICU. Cardiology Clinics 2024, 42: 253-271. PMID: 38631793, DOI: 10.1016/j.ccl.2024.02.010.Peer-Reviewed Original ResearchCan Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001)
Nguyen C, Molligoda B, Kim N, Kitlen E, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. Can Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206255.Peer-Reviewed Original ResearchThe Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014)
Fung C, Kitlen E, Nguyen C, Kim N, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. The Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206574.Peer-Reviewed Original ResearchEarly Serial Assessment of Aggregate Vasoactive Support and Mortality in Cardiogenic Shock: Insights From the Critical Care Cardiology Trials Network Registry
Patel S, Berg D, Bohula E, Baird-Zars V, Barsness G, Chaudhry S, Chonde M, Cooper H, Ginder C, Jentzer J, Kontos M, Miller P, Newby L, O’Brien C, Park J, Pierce M, Pisani B, Potter B, Shah K, Teuteberg J, Katz J, van Diepen S, Morrow D. Early Serial Assessment of Aggregate Vasoactive Support and Mortality in Cardiogenic Shock: Insights From the Critical Care Cardiology Trials Network Registry. Circulation Heart Failure 2024, 17: e011736. PMID: 38587438, DOI: 10.1161/circheartfailure.124.011736.Peer-Reviewed Original ResearchVasoactive-inotropic scoreCardiac intensive care unitVasoactive supportCardiogenic shockGradient of riskMechanical circulatory supportPatients admitted with CSCardiac intensive care unit admissionClinical decision-makingCritical Care Cardiology Trials NetworkIntensive care unitSCAI stagesNetwork registryCare unitTrials NetworkSOFA scoreMulticenter registryPrognostic associationMortalitySerial assessmentCirculatory supportSupportEarly changesScoresPatientsNoninvasive Ventilation in the Cardiac Intensive Care Unit.
Schenck C, Chouairi F, Dudzinski D, Miller P. Noninvasive Ventilation in the Cardiac Intensive Care Unit. Journal Of Intensive Care Medicine 2024, 8850666241243261. PMID: 38571399, DOI: 10.1177/08850666241243261.Peer-Reviewed Original ResearchCardiac intensive care unitNoninvasive ventilationRespiratory failureIntensive care unitContemporary cardiac intensive care unitsModality of noninvasive ventilationPatient populationAdult congenital heart diseaseCardiac intensive care unit admissionCare unitNoninvasive positive-pressure ventilationHigh-flow nasal cannulaHigh-risk patient populationUtilization of noninvasive ventilationRight ventricular dysfunctionCongenital heart diseaseManaging respiratory failureNoninvasive ventilation modalitiesRight ventricular failureInvasive mechanical ventilationSevere valvular diseasePositive pressure ventilationReducing extubation failureManagement of patientsPositive-pressure ventilationPropofol vs etomidate for induction prior to invasive mechanical ventilation in patients with acute myocardial infarction
Thomas A, Banna S, Shahu A, Ali T, Schenck C, Patel B, Notarianni A, Phommalinh M, Kochar A, Heck C, van Diepen S, Miller P. Propofol vs etomidate for induction prior to invasive mechanical ventilation in patients with acute myocardial infarction. American Heart Journal 2024, 272: 116-125. PMID: 38554762, DOI: 10.1016/j.ahj.2024.03.013.Peer-Reviewed Original ResearchConceptsAssociated with lower mortalityAcute myocardial infarctionInvasive mechanical ventilationLower mortalityUS national databaseClinical Data BaseMyocardial infarctionIll patient populationLength of stayCritically ill patient populationIn-hospital mortalityInverse probability treatmentOptimal induction agentInduction agentNational databaseClinical outcomesMechanical ventilationProbability treatmentPropensity weightingPatient populationRandomized trialsMortalityUtilization of propofolVentilator daysPropofol groupNeed for a Cardiogenic Shock Team Collaborative—Promoting a Team‐Based Model of Care to Improve Outcomes and Identify Best Practices
Senman B, Jentzer J, Barnett C, Bartos J, Berg D, Chih S, Drakos S, Dudzinski D, Elliott A, Gage A, Horowitz J, Miller P, Sinha S, Tehrani B, Yuriditsky E, Vallabhajosyula S, Katz J. Need for a Cardiogenic Shock Team Collaborative—Promoting a Team‐Based Model of Care to Improve Outcomes and Identify Best Practices. Journal Of The American Heart Association 2024, 13: e031979. PMID: 38456417, PMCID: PMC11009990, DOI: 10.1161/jaha.123.031979.Peer-Reviewed Original ResearchTeam-based models of careModels of careTeam-based modelPatient outcomesTime-sensitive conditionsCost of careTeam-based approachWell-resourced settingsEducation of stakeholdersImprove patient outcomesInfluence patient outcomesInformal careCare protocolsCardiogenic shockTeam-basedEvidence baseMultiple providersCareContemporary careTeam approachCardiac replacement therapyMultisystem organ failureSubgroup of patientsProfessional societiesProcedural proficiencyTransatlantic collaboration detailing research priorities in critical care cardiology
Miller P. Transatlantic collaboration detailing research priorities in critical care cardiology. European Heart Journal Acute Cardiovascular Care 2024, 13: 261-261. PMID: 38234272, DOI: 10.1093/ehjacc/zuae009.Peer-Reviewed Original Research
2023
Stress Ulcer Prophylaxis in Mechanically Ventilated Patients With Acute Myocardial Infarction
Banna S, Schenck C, Shahu A, Thomas A, Heck C, Tangredi R, Ali T, Miller P. Stress Ulcer Prophylaxis in Mechanically Ventilated Patients With Acute Myocardial Infarction. JACC Advances 2023, 3: 100750. PMID: 38939822, PMCID: PMC11198220, DOI: 10.1016/j.jacadv.2023.100750.Peer-Reviewed Original ResearchInvasive mechanical ventilationProton pump inhibitorsStress ulcer prophylaxisAcute myocardial infarctionUlcer prophylaxisVentilator-associated pneumoniaMyocardial infarctionVentilator daysST-segment elevation myocardial infarctionBackground Proton pump inhibitorsLess ventilator-associated pneumoniaVizient Clinical Data BaseObservation cohort studyProportion of patientsElevation myocardial infarctionMultivariable logistic regressionClostridium difficile infectionLower hospitalization costsClinical data baseCardiogenic shockHospital mortalityCohort studyMultivariate adjustmentHospitalization costsMechanical ventilationResearch Priorities in Critical Care Cardiology JACC Expert Panel
Miller P, Huber K, Bohula E, Krychtiuk K, Pöss J, Roswell R, Tavazzi G, Solomon M, Kristensen S, Morrow D, Care A. Research Priorities in Critical Care Cardiology JACC Expert Panel. Journal Of The American College Of Cardiology 2023, 82: 2329-2337. PMID: 38057075, PMCID: PMC10752230, DOI: 10.1016/j.jacc.2023.09.828.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitCritical care cardiologyHigh-quality evidencePatient populationIntensive care unitCritical care researchCare unitIll patientsSociety guidelinesClinical trialsPractice patternsCare researchExpert panelDiagnosisResearch prioritiesComorbiditiesPatientsPopulationLimited guidanceCliniciansCardiologyTrialsCare