2024
Epidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions
Berg D, Bohula E, Patel S, Alfonso C, Alviar C, Baird-Zars V, Barnett C, Barsness G, Bennett C, Chaudhry S, Fordyce C, Ghafghazi S, Gidwani U, Goldfarb M, Katz J, Menon V, Miller P, Newby L, Papolos A, Park J, Pierce M, Proudfoot A, Sinha S, Sridharan L, Thompson A, van Diepen S, Morrow D. Epidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions. European Heart Journal Acute Cardiovascular Care 2024, 13: 709-714. PMID: 39208447, PMCID: PMC11518926, DOI: 10.1093/ehjacc/zuae098.Peer-Reviewed Original ResearchCardiac intensive care unitSecondary CSConsensus definitionConcomitant cardiac arrestCritical Care Cardiology Trials NetworkRelevant to clinical practiceAcademic Research ConsortiumIn-hospital mortalityResearch ConsortiumCardiogenic shockIntensive care unitMultinational research networksCardiac arrestClinical practiceEvidence of hypoperfusionCare unitTrials NetworkTIMI Study GroupContemporary registryRegistryShock criteriaCS classificationStudy groupEpidemiologyClinical trialsOutcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units
Shahu A, Namburar S, Banna S, Harris A, Schenck C, Trejo-Paredes C, Thomas A, Ali T, Carnicelli A, Barnett C, Solomon M, Miller P. Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units. JACC Advances 2024, 3: 101199. PMID: 39238851, PMCID: PMC11375252, DOI: 10.1016/j.jacadv.2024.101199.Peer-Reviewed Original ResearchAcute myocardial infarctionAssociated with lower in-hospital mortalityIn-hospital mortalityLower in-hospital mortalityIntensive care unitMedical ICUPrimary diagnosis of acute myocardial infarctionMultivariable adjustmentCICU admissionInvasive mechanical ventilationVizient Clinical Data BaseBackground Acute myocardial infarctionDiagnosis of acute myocardial infarctionMultivariate logistic regressionMedical intensive care unitClinical outcomesMechanical ventilationCardiogenic shockClinical Data BaseMyocardial infarctionHospital sizeTriage of critically ill patientsMedian ventilator daysTeaching hospitalLogistic regressionArterial hyperoxia and mortality in the cardiac intensive care unit
Jentzer J, van Diepen S, Alviar C, Miller P, Metkus T, Geller B, Kashani K. Arterial hyperoxia and mortality in the cardiac intensive care unit. Current Problems In Cardiology 2024, 49: 102738. PMID: 39025170, DOI: 10.1016/j.cpcardiol.2024.102738.Peer-Reviewed Original ResearchCardiac intensive care unitIn-hospital mortalityIntensive care unitEvaluate predictors of in-hospital mortalityArterial hyperoxiaPaO2 >Mayo Clinic CICU patientsAssociated with increased in-hospital mortalityCare unitPredictors of in-hospital mortalityAssociated with higher in-hospital mortalityAssociated with adverse outcomesTime of CICU admissionAdmission PaO2Higher in-hospital mortalityCritically ill populationArterial partial pressure of oxygenPositive-pressure ventilationJ-shaped associationExposure to hyperoxiaCICU patientsArterial partial pressureCICU admissionEvaluate predictorsMedian PaO2Exposure to hyperoxemia and mortality in cardiac intensive care unit patients
Alviar C, Jentzer J, Van Diepen S, Metkus T, Miller P, Kashani K. Exposure to hyperoxemia and mortality in cardiac intensive care unit patients. European Heart Journal Acute Cardiovascular Care 2024, 13: zuae036.138. DOI: 10.1093/ehjacc/zuae036.138.Peer-Reviewed Original ResearchIn-hospital mortalityCardiac intensive care unitCardiac intensive care unit admissionJ-shaped associationJ-shaped relationshipCritical care settingCardiac intensive care unit patientsCare settingsAssociated with increased in-hospital mortalityCare conditionsInpatient deathCharlson Comorbidity IndexMayo Clinic CICU patientsIntensive care unit patientsAssociated with adverse outcomesAdmission diagnosisLogistic regressionCICU patientsExposure to hyperoxemiaHigher mortalityPrimary outcomeIntensive care unitIll cardiac patientsGeneral critical care settingCardiac patientsTracheostomy in Patients with Acute Myocardial Infarction and Respiratory Failure
Grammatico M, Banna S, Shahu A, Gastanadui M, Jimenez J, Heck C, Arias-Olson A, Thomas A, Ali T, Miller P. Tracheostomy in Patients with Acute Myocardial Infarction and Respiratory Failure. Journal Of Intensive Care Medicine 2024, 39: 1131-1137. PMID: 38715423, DOI: 10.1177/08850666241253202.Peer-Reviewed Original ResearchDays of tracheostomyInvasive mechanical ventilationIn-hospital mortalityAcute myocardial infarctionTiming of tracheostomyRespiratory failureAntiplatelet regimensMyocardial infarctionAssociated with lower in-hospital mortalityIncidence of tracheostomyLower in-hospital mortalityProportion of patientsIncidence of patientsDiagnosis of acute myocardial infarctionDAPT interruptionTracheostomy complicationsBlood transfusionOpen tracheostomyAntiplatelet therapyMechanical ventilationMultivariable adjustmentDAPT usePrimary diagnosis of acute myocardial infarctionClinical Data BaseTracheostomyPropofol vs etomidate for induction prior to invasive mechanical ventilation in patients with acute myocardial infarction
Thomas A, Banna S, Shahu A, Ali T, Schenck C, Patel B, Notarianni A, Phommalinh M, Kochar A, Heck C, van Diepen S, Miller P. Propofol vs etomidate for induction prior to invasive mechanical ventilation in patients with acute myocardial infarction. American Heart Journal 2024, 272: 116-125. PMID: 38554762, DOI: 10.1016/j.ahj.2024.03.013.Peer-Reviewed Original ResearchConceptsAssociated with lower mortalityAcute myocardial infarctionInvasive mechanical ventilationLower mortalityUS national databaseClinical Data BaseMyocardial infarctionIll patient populationLength of stayCritically ill patient populationIn-hospital mortalityInverse probability treatmentOptimal induction agentInduction agentNational databaseClinical outcomesMechanical ventilationProbability treatmentPropensity weightingPatient populationRandomized trialsMortalityUtilization of propofolVentilator daysPropofol group
2021
Higher CICU mechanical ventilation volumes are associated with lower in-hospital mortality
Nandiwada S, Islam S, Jentzer J, Miller P, Fordyce C, Lawler P, Alviar C, Sun L, Dover D, Kaul P, Van Diepen S. Higher CICU mechanical ventilation volumes are associated with lower in-hospital mortality. European Heart Journal Acute Cardiovascular Care 2021, 10: zuab020.161. DOI: 10.1093/ehjacc/zuab020.161.Peer-Reviewed Original ResearchCardiac intensive care unitCICU LOSIn-hospital mortalityAssociated with lower in-hospital mortalityProlonged MVLower in-hospital mortalityProportion of patientsMechanical ventilationRespiratory failureVolume centersCardiac intensive care unit lengthCardiac intensive care unit admissionIncidence of respiratory failureNon-invasive mechanical ventilationAssociated with reduced mortalityInvasive mechanical ventilationLow-volume centersIntensive care unitHigh-volume hospitalsCardiac intensive care unit populationPopulation-based dataSurgical ICUOdds ratioAcademic centersCare unit