2017
The Effect of Labour Induction on the Risk of Caesarean Delivery
Danilack V, Dore D, Triche E, Muri J, Phipps M, Savitz D. The Effect of Labour Induction on the Risk of Caesarean Delivery. Obstetric Anesthesia Digest 2017, 37: 83. DOI: 10.1097/01.aoa.0000515754.91071.a0.Peer-Reviewed Original ResearchRisk of CDLabor inductionCesarean deliveryIntrauterine growth restrictionCaesarean deliveryExpectant managementPostterm pregnancyUnderwent inductionGrowth restrictionPropensity score methodsMedical reasonsPropensity scoreEffect estimatesPreeclampsiaRiskInductionPresent studyAssociationScore methodPotential benefitsIndicationsDeliveryOligohydramniosPregnancyFetuses
2016
Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study
Spracklen C, Ryckman K, Triche E, Saftlas A. Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study. Maternal And Child Health Journal 2016, 20: 1193-1202. PMID: 26910608, PMCID: PMC5538351, DOI: 10.1007/s10995-016-1919-y.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaLeisure-time PAGestational hypertensionSedentary activitiesMedical chart reviewCase-control studyGestational hypertensiveObjectivePhysical activityPreeclampsia resultsPregnancy hypertensionPrepregnancy BMINormotensive womenChart reviewHypertension riskPreeclampsia riskSubsequent riskPreeclampsiaEpidemiologic studiesPA exposurePhysical activityMultinomial logistic regressionHypertensionControl studyDisease statusBirth records
2015
The Rising Burden of Preeclampsia in the United States Impacts Both Maternal and Child Health
Shih T, Peneva D, Xu X, Sutton A, Triche E, Ehrenkranz RA, Paidas M, Stevens W. The Rising Burden of Preeclampsia in the United States Impacts Both Maternal and Child Health. American Journal Of Perinatology 2015, 33: 329-338. PMID: 26479171, DOI: 10.1055/s-0035-1564881.Peer-Reviewed Original ResearchConceptsEarly-onset preeclampsiaNumerous adverse health consequencesHealth consequencesConsiderable perinatal morbidityAdverse health consequencesEstimates of burdenSeverity of outcomePerinatal morbidityPreterm deliveryPreterm birthTerm pregnancyMaternal mortalityUS incidencePreeclampsiaChild healthEffective treatmentEconomic burdenRising BurdenSocial burdenHealth careBurdenMortalityUnited StatesHealthMothersGenetic Risk Score for Essential Hypertension and Risk of Preeclampsia
Smith CJ, Saftlas AF, Spracklen CN, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia. American Journal Of Hypertension 2015, 29: 17-24. PMID: 26002928, PMCID: PMC4692983, DOI: 10.1093/ajh/hpv069.Peer-Reviewed Original ResearchConceptsDiastolic blood pressureSystolic blood pressureGenetic risk scoreRisk of preeclampsiaBlood pressureEssential hypertensionRisk scoreNormotensive pregnant controlsHypertensive complicationsArterial pressurePregnant controlsWeeks' gestationPreeclamptic casesHypertensive stateEpidemiological evidenceHypertensionPreeclampsiaUS populationNonsignificant associationGenetic risk lociGenetic susceptibilitySwab samplesBuccal swab samplesGenetic riskRegression analysis
2013
Maternal–fetal HLA sharing and preeclampsia: variation in effects by seminal fluid exposure in a case–control study of nulliparous women in Iowa
Triche E, Harland K, Field E, Rubenstein L, Saftlas A. Maternal–fetal HLA sharing and preeclampsia: variation in effects by seminal fluid exposure in a case–control study of nulliparous women in Iowa. Journal Of Reproductive Immunology 2013, 101: 111-119. PMID: 23998333, PMCID: PMC4060772, DOI: 10.1016/j.jri.2013.06.004.Peer-Reviewed Original ResearchConceptsCase-control studyHLA sharingSemen exposureNulliparous womenClass IHLA typingComplete HLA typingMaternal-fetal histocompatibilityOdds of preeclampsiaMother-baby pairsHLA-A matchingVaginal exposureNormotensive controlsSuccessful pregnancyPreeclampsia casesContraceptive usePreeclampsiaEligibility criteriaFluid exposureIngestion practicesClass IIMultivariate modelStudy sampleExposure historyType of practiceExploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1)
Paidas MJ, Sibai BM, Triche EW, Frieling J, Lowry S, Group T. Exploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1). American Journal Of Reproductive Immunology 2013, 69: 539-544. PMID: 23444920, DOI: 10.1111/aji.12091.Peer-Reviewed Original ResearchConceptsProspective Randomized EvaluationAntithrombin replacementWeeks' gestationRandomized EvaluationRecombinant antithrombinTreatment of preeclampsiaRecombinant human ATExpectant managementPreterm preeclampsiaPrimary endpointMaternal indicationsGestational ageStudy enrollmentAT therapyPreeclampsia studyPreeclampsiaGestationHuman ATAT replacementPharmacokinetic activityAntithrombinEfficacySafetyLaboratory assaysDelivery
2005
Immunogenetic Determinants of Preeclampsia and Related Pregnancy Disorders
Saftlas A, Beydoun H, Triche E. Immunogenetic Determinants of Preeclampsia and Related Pregnancy Disorders. Obstetrics And Gynecology 2005, 106: 162-172. PMID: 15994633, DOI: 10.1097/01.aog.0000167389.97019.37.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionRisk of preeclampsiaGrowth restrictionHuman leukocyte antigen (HLA) allele frequenciesMaternal homozygosityPossible etiologic factorsHLA-DR locusSpecific HLA allelesAdditional pertinent studiesBasic science research studiesHLA allele frequenciesImmunogenetic factorsOriginal research studiesExposure definitionPregnancy disordersEtiologic factorsHLA genotypeSTUDY SELECTIONHLA sharingImmunogenetic determinantsPreeclampsiaHLA allelesPubMed databaseYielded inconsistent resultsComputerized search
2004
Multiple sexual partners and early menarche are risk factors for preeclampsia in an African population
Anyikam A, Triche E, Moodley J, Norwitz E. Multiple sexual partners and early menarche are risk factors for preeclampsia in an African population. American Journal Of Obstetrics And Gynecology 2004, 191: s43. DOI: 10.1016/j.ajog.2004.10.023.Peer-Reviewed Original Research
2000
Abortion and Its Effect on Risk of Preeclampsia and Transient Hypertension
Eras J, Saftlas A, Triche E, Hsu C, Risch H, Bracken M. Abortion and Its Effect on Risk of Preeclampsia and Transient Hypertension. Epidemiology 2000, 11: 36-43. PMID: 10615841, DOI: 10.1097/00001648-200001000-00009.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaTransient hypertensionNulliparous womenDecreased riskMore abortionsPregnancy-related risk factorsHistory of abortionHypertensive disordersWeeks' gestationGestational ageSubsequent pregnancyPrenatal careRisk factorsObstetric practicePrior abortionMonths gestationPreeclampsiaHypertensionInduced abortionReproductive historyReferent groupProtective factorsGestationWomenAbortion