2022
Quantification of upper limb dysfunction in the activities of the daily living in persons with multiple sclerosis
Pisa M, Ruiz J, DeLuca G, de Andres Crespo M, DelMastro H, Olson K, Triche E, Lo A. Quantification of upper limb dysfunction in the activities of the daily living in persons with multiple sclerosis. Multiple Sclerosis And Related Disorders 2022, 63: 103917. PMID: 35671673, DOI: 10.1016/j.msard.2022.103917.Peer-Reviewed Original ResearchConceptsNine-Hole Peg TestFinger-nose testUL dysfunctionMultiple sclerosisDaily livingDisease severity subgroupsUpper limb functionUpper limb dysfunctionCharacteristic curve analysisJonckheere-Terpstra testUL functionDisease stageLimb functionGrip strengthPeg TestClinical trialsDisease progressionLimb dysfunctionGlobal disabilityMultivariate regression modelKruskal-Wallis testPredictive valueSeverity subgroupsLinear regression analysisDysfunction
2016
Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER
Triche E, Ruiz J, Olson K, Lo A. Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER. Clinical Neuropharmacology 2016, 39: 73-80. PMID: 26818040, DOI: 10.1097/wnf.0000000000000130.Peer-Reviewed Original ResearchConceptsDalfampridine extended releaseMultiple sclerosisWalk respondersObservational pre-post studyPre-post studyPerformance ScaleDegenerative neurological conditionDalfampridine-ERMS careFatigue scoresObservational studyResponder statusWeek 14Neurological conditionsSignificant improvementCognitive processing speedSelf-reported cognitionMood scoresWeeksSclerosisSDMTRespondersMoodDrugsDepression
2015
Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders
Lo A, Ruiz J, Koenig C, Anderson B, Olson K, Triche E. Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders. Journal Of The Neurological Sciences 2015, 356: 77-82. PMID: 26139339, DOI: 10.1016/j.jns.2015.06.008.Peer-Reviewed Original ResearchConceptsNon-dominant sideMultiple sclerosisMultiple Sclerosis Walking Scale-12Six-Spot Step TestD-EREffects of dalfampridineMinute walk testHole Peg TestRoutine clinical careWalk respondersWalk testGait impairmentAmbulatory personsPeg TestGross dexterityClinical carePotential treatmentScale-12Block TestSclerosisGaitStep testRespondersFurther investigationSignificant improvementA Pilot Study: examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis
Mandelbaum R, Triche E, Fasoli S, Lo A. A Pilot Study: examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis. Disability And Rehabilitation 2015, 38: 218-222. PMID: 25875049, DOI: 10.3109/09638288.2015.1035457.Peer-Reviewed Original ResearchConceptsDynamic Gait IndexPhysical activity adherenceMultiple sclerosisPhysical activityDance interventionActivities-specific Balance Confidence ScaleGodin Leisure Time QuestionnaireIssues of tolerabilityBalance Confidence ScaleEnjoyable physical activityActivity adherenceMS symptomsGait IndexNeurological impairmentMS populationElderly populationFeasible interventionPilot studyConfidence ScaleTolerabilityInterventionNeurodegenerative populationsSclerosisTime QuestionnaireBehavioral changes
2013
Combination of Robot-Assisted and Conventional Body-Weight–Supported Treadmill Training Improves Gait in Persons With Multiple Sclerosis
Ruiz J, Labas M, Triche E, Lo A. Combination of Robot-Assisted and Conventional Body-Weight–Supported Treadmill Training Improves Gait in Persons With Multiple Sclerosis. Journal Of Neurologic Physical Therapy 2013, 37: 187-193. PMID: 24189336, DOI: 10.1097/npt.0000000000000018.Peer-Reviewed Original ResearchConceptsFunctional Reach TestGait trainingDT groupTreadmill trainingWalk testTherapy groupIT groupRobot-assisted treadmill trainingImmediate therapy groupConcurrent comparison groupMajority of personsQuality of lifePre-post improvementsMultiple sclerosisEffective therapyReach testOutcome measuresBody weightFRT distancePhase ISame sessionVideo AbstractComparison groupPhase IIRobot-Assisted
2011
Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis
Wier L, Hatcher M, Triche E, Lo A. Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis. The Journal Of Rehabilitation Research And Development 2011, 48: 483. PMID: 21674396, DOI: 10.1682/jrrd.2010.03.0035.Peer-Reviewed Original ResearchConceptsQuality of lifeTreadmill trainingPhysical component summary scoreComponent summary scoresMultiple sclerosis patientsQOL outcome measuresTraining sessionsGait dysfunctionSclerosis patientsMultiple sclerosisGait impairmentBWSTTOutcome measuresQOL measuresSummary scoresLongitudinal changesPilot studySignificant differencesQoLR groupSignificant improvementSessionsSclerosisPatientsDysfunction
2010
Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis
Gianfrancesco M, Triche E, Fawcett J, Labas M, Patterson T, Lo A. Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis. Gait & Posture 2010, 33: 140-142. PMID: 20952198, DOI: 10.1016/j.gaitpost.2010.09.016.Peer-Reviewed Original ResearchConceptsGait parametersPreferred speedMultiple sclerosisGait impairmentMS populationBilateral coordinationAdditional trialsStance timeMS participantsCane useSwing timeStride lengthDouble supportDaily activitiesStep length ratioSingle supportAssistive devicesParticipantsIndividualsSclerosisMaximal speedImpairmentTrialsDaily
2008
Improving Gait in Multiple Sclerosis Using Robot-Assisted, Body Weight Supported Treadmill Training
Lo A, Triche E. Improving Gait in Multiple Sclerosis Using Robot-Assisted, Body Weight Supported Treadmill Training. Neurorehabilitation And Neural Repair 2008, 22: 661-671. PMID: 18971381, DOI: 10.1177/1545968308318473.Peer-Reviewed Original ResearchConceptsExpanded Disability Status ScaleMultiple sclerosisGait outcomesGait impairmentTreadmill trainingGait trainingTreatment groupsBody weightBaseline Expanded Disability Status ScaleKurtzke Expanded Disability Status ScalePrimary progressive multiple sclerosisDouble limb support timeProgressive gait impairmentProgressive multiple sclerosisDisability Status ScaleMajority of patientsSmall pilot studyGait functionStatus ScaleTreatment gapAffected limbOutpatient interventionStudy populationSupport timeCrossover design