2023
Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements
Sherman B, Harris B, Turk-Browne N, Sinha R, Goldfarb E. Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements. Journal Of Neuroscience 2023, 43: 7198-7212. PMID: 37813570, PMCID: PMC10601369, DOI: 10.1523/jneurosci.0916-23.2023.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMemory enhancementEpisodic memoryAssociative memoryEpisodic memory encodingBrain regionsHigh-resolution functional magnetic resonance imagingHuman hippocampusHigh-resolution fMRIStress-related hormone cortisolHormone cortisolMemory benefitsEmotional memoryMemory encodingEmotional eventsEmotional associationsHippocampal representationsHippocampal signaturesFunctional neuroimagingHippocampal mechanismsStressful eventsFunctional connectivityHippocampal functionMemory formationSalient information
2021
Elemental and configural threat learning bias extinction generalization
Goldfarb EV, Blow T, Dunsmoor JE, Phelps EA. Elemental and configural threat learning bias extinction generalization. Neurobiology Of Learning And Memory 2021, 180: 107405. PMID: 33609739, PMCID: PMC8076085, DOI: 10.1016/j.nlm.2021.107405.Peer-Reviewed Original ResearchConceptsExtinction generalizationCompound cueNegative emotional eventsTime of learningGroups of participantsMultitude of detailsThreat conditioningElemental learningAversive outcomesEmotional eventsExtinction strategiesExtinction taskAversive eventsEmotional experienceThreat responsesEmotional responsesAbsence of shockCuesMemorySingle representationParticipantsLearningToneImportant implicationsExtinction
2020
Hippocampal seed connectome-based modeling predicts the feeling of stress
Goldfarb EV, Rosenberg MD, Seo D, Constable RT, Sinha R. Hippocampal seed connectome-based modeling predicts the feeling of stress. Nature Communications 2020, 11: 2650. PMID: 32461583, PMCID: PMC7253445, DOI: 10.1038/s41467-020-16492-2.Peer-Reviewed Original Research
2019
Acute Stress Throughout the Memory Cycle: Diverging Effects on Associative and Item Memory
Goldfarb EV, Tompary A, Davachi L, Phelps EA. Acute Stress Throughout the Memory Cycle: Diverging Effects on Associative and Item Memory. Journal Of Experimental Psychology General 2019, 148: 13-29. PMID: 30221962, PMCID: PMC6312485, DOI: 10.1037/xge0000472.Peer-Reviewed Original ResearchConceptsItem memoryAssociative memoryAssociative recognition taskAcute stressForms of memoryStress-induced cortisolAcute stress effectsNeutral objectsNegative wordsRecognition taskSubjective arousalSubjects designMemoryItemsDifferent patternsArousalAssociativeWordsTaskParticipantsStress effectsRelationshipCortisolQuadratic relationshipKey differences
2017
Acute Stress Time-dependently Modulates Multiple Memory Systems
Goldfarb EV, Mendelevich Y, Phelps EA. Acute Stress Time-dependently Modulates Multiple Memory Systems. Journal Of Cognitive Neuroscience 2017, 29: 1877-1894. PMID: 28699809, DOI: 10.1162/jocn_a_01167.Peer-Reviewed Original ResearchLow lifetime stress exposure is associated with reduced stimulus–response memory
Goldfarb EV, Shields GS, Daw ND, Slavich GM, Phelps EA. Low lifetime stress exposure is associated with reduced stimulus–response memory. Learning & Memory 2017, 24: 162-168. PMID: 28298555, PMCID: PMC5362698, DOI: 10.1101/lm.045179.117.Peer-Reviewed Original ResearchConceptsLifetime stress exposureStimulus-response memoryStress exposureLifetime stressCumulative lifetime stress exposureStimulus-response associationsForms of psychopathologyYoung adultsHigh lifetime stressLow stress exposureCumulative stress exposureContext memoryMemory performanceDiminished resilienceSR associationsNegative outcomesMemoryModerate levelsNegative effectsLow levelsComputational modelingLow stressAdultsAssessment systemCognitionStress and Cognitive Flexibility: Cortisol Increases Are Associated with Enhanced Updating but Impaired Switching
Goldfarb EV, Froböse MI, Cools R, Phelps EA. Stress and Cognitive Flexibility: Cortisol Increases Are Associated with Enhanced Updating but Impaired Switching. Journal Of Cognitive Neuroscience 2017, 29: 14-24. PMID: 27576026, DOI: 10.1162/jocn_a_01029.Peer-Reviewed Original ResearchConceptsCognitive flexibilityDifferent task demandsTask demandsParticipants' cortisol responsesAcute stress manipulationCortisol responseDMS taskStress-related increasesStress manipulationMultifaceted constructImpaired switchingEffects of stressPFC functionSubjects designDimensions of flexibilityWorse performanceDorsal striatumAcute stressCortisol increaseRelevant informationTaskMost studiesParticipantsConstructsParadigm
2016
Memory-Guided Attention: Independent Contributions of the Hippocampus and Striatum
Goldfarb EV, Chun MM, Phelps EA. Memory-Guided Attention: Independent Contributions of the Hippocampus and Striatum. Neuron 2016, 89: 317-324. PMID: 26777274, PMCID: PMC4871761, DOI: 10.1016/j.neuron.2015.12.014.Peer-Reviewed Original ResearchConceptsContext memoryMemory-guided attentionFunctional magnetic resonance imagingStimulus-response associationsVisual search taskMedial temporal lobeFacilitate attentionAttention benefitsIndividual differencesSearch taskMemory systemTemporal lobeMemoryIndependent contributionNovel evidenceFuture encountersReinforcement learningAttentionMagnetic resonance imagingStriatumHippocampusResonance imagingTaskLearningFacilitation
2014
Gaps in Preparedness of Clergy and Healthcare Providers to Address Mental Health Needs of Returning Service Members
Chevalier L, Goldfarb E, Miller J, Hoeppner B, Gorrindo T, Birnbaum RJ. Gaps in Preparedness of Clergy and Healthcare Providers to Address Mental Health Needs of Returning Service Members. Journal Of Religion And Health 2014, 54: 327-338. PMID: 25112409, DOI: 10.1007/s10943-014-9917-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain InjuriesClergyDepressive DisorderFemaleFocus GroupsHealth PersonnelHealth Services Needs and DemandHumansInterdisciplinary CommunicationMaleMental DisordersMiddle AgedProfessional CompetenceReferral and ConsultationReligion and MedicineSleep Initiation and Maintenance DisordersStress Disorders, Post-TraumaticSuicideSuicide PreventionVeteransAutonomic Arousal and Learning in Web‐Based Simulation: A Feasibility Study
Gorrindo T, Chevalier L, Goldfarb E, Hoeppner BB, Birnbaum RJ. Autonomic Arousal and Learning in Web‐Based Simulation: A Feasibility Study. Journal Of Continuing Education In The Health Professions 2014, 34: s17-s22. PMID: 24935879, DOI: 10.1002/chp.21234.Peer-Reviewed Original Research
2013
Interprofessional Differences in Disposition Decisions: Results From a Standardized Web-Based Patient Assessment
Gorrindo T, Goldfarb E, Chevalier L, Hoeppner BB, Birnbaum RJ, Meller B, Alpert JE, Herman J, Weiss AP. Interprofessional Differences in Disposition Decisions: Results From a Standardized Web-Based Patient Assessment. Psychiatric Services 2013, 64: 808-811. PMID: 23903607, DOI: 10.1176/appi.ps.201200461.Peer-Reviewed Original ResearchConceptsPsychiatric patientsDisposition decisionsLevel of followTypes of cliniciansMental health professionalsPatient assessmentViolence risk assessmentHigh riskHealth professionalsPatientsClinician actionsPsychiatry departmentInterprofessional differencesCliniciansCareTraining differencesTraining backgroundFurther trainingVirtual patientsImportant determinantHigh levelsHospitalizationRisk assessmentFollowDifferences