2024
Drawbacks to Strengthening Neural Salience Encoding: A Link Between Cortisol and Risky Drinking
Harris B, Sinha R, Goldfarb E. Drawbacks to Strengthening Neural Salience Encoding: A Link Between Cortisol and Risky Drinking. Journal Of Neuroscience 2024, 44: e1027242024. PMID: 39147591, PMCID: PMC11450530, DOI: 10.1523/jneurosci.1027-24.2024.Peer-Reviewed Original ResearchAlcohol motivationInfluence later behaviorEnhance memorySalience responseFemale social drinkersAlcohol drinkingEmotionally salient experiencesResponse to alcoholDouble-blind cross-over designMemory biasSalient memoriesAlcohol-related eventsRisky alcohol drinkingSocial drinkersMotivated behaviorMaladaptive consequencesLateral behaviorCross-over designRisky drinkingMemoryRodent modelsHuman researchSalienceRisky drinkersCortisol
2023
Perceptual Generalization of Alcohol-Related Value Characterizes Risky Drinkers
Kang S, Larrabee G, Nair S, Goldfarb E. Perceptual Generalization of Alcohol-Related Value Characterizes Risky Drinkers. Psychological Science 2023, 34: 1146-1162. PMID: 37682597, PMCID: PMC10985388, DOI: 10.1177/09567976231181516.Peer-Reviewed Original ResearchSurprise recognition memory testAlcohol-related associationsRecognition memory testAlcohol-related imagesRisky drinkingPerceptual generalizationMemory testPerceptual similarityRisky drinkersNovel situationsAdaptive behaviorMaladaptive responsesOnline experimentPast experienceRisky patternsOvergeneralizationDrinkersDrinkingParticipantsConditioningIndividualsOutcomesExperienceAlcoholBias
2022
High-Risk Drinkers Engage Distinct Stress-Predictive Brain Networks
Goldfarb EV, Scheinost D, Fogelman N, Seo D, Sinha R. High-Risk Drinkers Engage Distinct Stress-Predictive Brain Networks. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 805-813. PMID: 35272096, PMCID: PMC9378362, DOI: 10.1016/j.bpsc.2022.02.010.Peer-Reviewed Original ResearchConceptsRisky drinkersHigh-risk drinkersBrain networksMajor public health problemExcessive alcohol intakeWhole-brain functional connectivityPublic health problemEarly preventive interventionsAlcohol use disorderDaily ecological momentary assessmentsAlcohol intakeControl subjectsRisky drinking behaviorsEmotional stress responsesUse disordersEarly markerHealth problemsPreventive interventionsBrain circuitryLight drinkersFunctional connectivityStress protocolHeavy drinkingDrinkersEcological momentary assessment