2023
Binge drinking is associated with higher cortisol and lower hippocampal and prefrontal gray matter volume: Prospective association with future alcohol intake
Fan S, Goldfarb E, Lacadie C, Fogelman N, Seo D, Sinha R. Binge drinking is associated with higher cortisol and lower hippocampal and prefrontal gray matter volume: Prospective association with future alcohol intake. Neurobiology Of Stress 2023, 25: 100540. PMID: 37323647, PMCID: PMC10265520, DOI: 10.1016/j.ynstr.2023.100540.Peer-Reviewed Original ResearchGray matter volumeDorsal lateral prefrontal cortexAlcohol use disorderSmaller gray matter volumeAlcohol intakePrefrontal gray matter volumeBinge drinkingFuture alcohol intakeMatter volumeBilateral dorsal lateral prefrontal cortexCortisol levelsStructural grey matter volumeHigher cortisolWhole-brain voxel-based morphometryAcute alcohol intakeLower gray matter volumeHigh-resolution structural MRIVoxel-based morphometryRegional gray matter volumePosterior parietal cortexMotor cortexSupplementary motorModerate drinkersUse disordersDrinking days
2022
High-Risk Drinkers Engage Distinct Stress-Predictive Brain Networks
Goldfarb EV, Scheinost D, Fogelman N, Seo D, Sinha R. High-Risk Drinkers Engage Distinct Stress-Predictive Brain Networks. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 805-813. PMID: 35272096, PMCID: PMC9378362, DOI: 10.1016/j.bpsc.2022.02.010.Peer-Reviewed Original ResearchConceptsRisky drinkersHigh-risk drinkersBrain networksMajor public health problemExcessive alcohol intakeWhole-brain functional connectivityPublic health problemEarly preventive interventionsAlcohol use disorderDaily ecological momentary assessmentsAlcohol intakeControl subjectsRisky drinking behaviorsEmotional stress responsesUse disordersEarly markerHealth problemsPreventive interventionsBrain circuitryLight drinkersFunctional connectivityStress protocolHeavy drinkingDrinkersEcological momentary assessment