2020
Association of symptom severity, pain and other behavioral and medical comorbidities with diverse measures of functioning among adults with post-traumatic stress disorder
Manhapra A, Stefanovics EA, Rhee TG, Rosenheck RA. Association of symptom severity, pain and other behavioral and medical comorbidities with diverse measures of functioning among adults with post-traumatic stress disorder. Journal Of Psychiatric Research 2020, 134: 113-120. PMID: 33383494, DOI: 10.1016/j.jpsychires.2020.12.063.Peer-Reviewed Original ResearchConceptsMental health composite scoresPhysical function scoresPost-traumatic stress disorderSubstance use disordersMedical comorbiditiesPain interferencePTSD symptomsStatistical Manual-5 (DSM-5) criteriaSymptom severityMental health-related qualityStress disorderPast-year post-traumatic stress disorderShort Form-12Health-related qualityNational Epidemiologic SurveyNegative associationCommon comorbiditiesChronic painForm-12Medical illnessSubstantial disabilityPsychiatric comorbidityPTSD symptom severityFunction scoresIndependent associationImpact of cannabis on non-medical opioid use and symptoms of posttraumatic stress disorder: a nationwide longitudinal VA study
De Aquino JP, Sofuoglu M, Stefanovics EA, Rosenheck RA. Impact of cannabis on non-medical opioid use and symptoms of posttraumatic stress disorder: a nationwide longitudinal VA study. The American Journal Of Drug And Alcohol Abuse 2020, 46: 812-822. PMID: 33035104, DOI: 10.1080/00952990.2020.1818248.Peer-Reviewed Original ResearchConceptsNon-medical opioid usePosttraumatic stress disorderOpioid useNon-medical opioidsPTSD symptomsCannabis useStress disorderSubstance useBaseline cannabis useImpact of cannabisSevere PTSD symptomsIntensive PTSD treatmentMore PTSD symptomsPTSD treatmentU.S. veteransSymptomsVA studyCannabisVeteransOpioidsSubstitution agentsBaselineDaysDisordersTreatmentGender Differences in Outcomes Following Specialized Intensive PTSD Treatment in the Veterans Health Administration
Stefanovics EA, Rosenheck RA. Gender Differences in Outcomes Following Specialized Intensive PTSD Treatment in the Veterans Health Administration. Psychological Trauma Theory Research Practice And Policy 2020, 12: 272-280. PMID: 31282719, DOI: 10.1037/tra0000495.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderTotal PTSD symptom scoresPTSD symptomsNational program evaluation dataVeterans Health AdministrationVeterans Health Administration programGreater improvementPTSD symptom scoresIntensive PTSD treatmentSymptom scoresTreatment outcomesProgram participationMale veteransGender differencesHealth AdministrationPTSD treatmentFemale veteransPTSD programProgram evaluation dataMedium effect size differencesStress disorderGender-based differencesEffect size differencesSubstance useStudy sample
2019
Comparing Outcomes of Women‐Only and Mixed‐Gender Intensive Posttraumatic Stress Disorder Treatment for Female Veterans
Stefanovics EA, Rosenheck RA. Comparing Outcomes of Women‐Only and Mixed‐Gender Intensive Posttraumatic Stress Disorder Treatment for Female Veterans. Journal Of Traumatic Stress 2019, 32: 606-615. PMID: 31361360, DOI: 10.1002/jts.22417.Peer-Reviewed Original ResearchConceptsFemale veteransMixed-gender programsOutcomes of womenNational program evaluation dataPosttraumatic stress disorder (PTSD) treatmentProgram entryLonger lengthTotal PTSD symptomsPTSD total scoreBaseline characteristicsPrimary outcomePTSD symptom levelsComparing outcomesSecondary measuresWomen veteransAssessment subscaleDisorders ProgramPosttraumatic Stress Disorder (CR for PTSD) programDisorder treatmentOutcome assessmentSuperior outcomesProgram evaluation dataPTSD symptomsSymptom levelsTotal score
2018
Polysubstance Use Among Veterans in Intensive PTSD Programs: Association With Symptoms and Outcomes Following Treatment
Bhalla IP, Stefanovics EA, Rosenheck RA. Polysubstance Use Among Veterans in Intensive PTSD Programs: Association With Symptoms and Outcomes Following Treatment. Journal Of Dual Diagnosis 2018, 15: 36-45. PMID: 30444189, DOI: 10.1080/15504263.2018.1535150.Peer-Reviewed Original ResearchConceptsPolysubstance useTotal daysSubstance usePTSD symptomsInnovative trial designsAddictive substancesPolysubstance use disorderMore total daysSevere PTSD symptomsBaseline characteristicsSuch patientsPTSD symptom severitySevere symptomsUse disordersDual diagnosisTrial designDifferent addictive substancesDisorders ProgramPosttraumatic Stress Disorder (CR for PTSD) programPatientsComplex interventionsSimilar associationBivariate analysisPTSD programSymptom severity
2016
Correlates of Improvement in Substance Abuse Among Dually Diagnosed Veterans With Post-Traumatic Stress Disorder in Specialized Intensive VA Treatment
Coker KL, Stefanovics E, Rosenheck R. Correlates of Improvement in Substance Abuse Among Dually Diagnosed Veterans With Post-Traumatic Stress Disorder in Specialized Intensive VA Treatment. Psychological Trauma Theory Research Practice And Policy 2016, 8: 41-48. PMID: 26121176, PMCID: PMC4487392, DOI: 10.1037/tra0000061.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityDiagnosis, Dual (Psychiatry)HumansLinear ModelsMiddle AgedMultivariate AnalysisPsychiatric Status Rating ScalesPsychotropic DrugsStress Disorders, Post-TraumaticSubstance-Related DisordersTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsVeteransViolenceConceptsPost-traumatic stress disorderSubstance abuseEvidence-based substance abuse treatmentStress disorderSevere post-traumatic stress disorderPTSD symptomsProper discharge planningDuration of treatmentCorrelates of improvementAddiction Severity Index AlcoholSubstance use disordersSubstance abuse treatmentEffect sizeDischarge planningPsychiatric medicationsImproved outcomesUse disordersBetter outcomesSynergistic treatment effectSubstance use measuresMultivariate analysisVA treatmentPTSD programAbuse treatmentViolent behavior
2015
Treatment outcomes for veterans with PTSD and substance use: Impact of specific substances and achievement of abstinence
Manhapra A, Stefanovics E, Rosenheck R. Treatment outcomes for veterans with PTSD and substance use: Impact of specific substances and achievement of abstinence. Drug And Alcohol Dependence 2015, 156: 70-77. PMID: 26429726, PMCID: PMC4633308, DOI: 10.1016/j.drugalcdep.2015.08.036.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderAchievement of abstinenceEffect of abstinenceTreatment outcomesSubstance useRates of abstinenceNational program evaluationSubstance abuse groupClinical outcomesBaseline variablesAnalysis of covariancePTSD patientsSpecific substancesMedical problemsPTSD programStress disorderAbstinencePTSD symptomsScant longitudinal dataUse outcomesSelf-reported dataAbuse groupOutcomesSignificant differencesGreater improvementMarijuana use is associated with worse outcomes in symptom severity and violent behavior in patients with posttraumatic stress disorder.
Wilkinson ST, Stefanovics E, Rosenheck RA. Marijuana use is associated with worse outcomes in symptom severity and violent behavior in patients with posttraumatic stress disorder. The Journal Of Clinical Psychiatry 2015, 76: 1174-80. PMID: 26455669, PMCID: PMC6258013, DOI: 10.4088/jcp.14m09475.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPTSD symptomsSymptom severityPTSD symptom severityWorse outcomesObservational studyMarijuana useStress disorderAlcohol useRelevant baseline covariatesWorse PTSD symptomsEffect sizeViolent behaviorBaseline characteristicsIntensive treatmentPrevention of useMeasures of alcoholAnalysis of covarianceDrug useAdmissionBaseline covariatesSymptomsTreatment programRelevant covariatesMedical marijuana