1997
Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: Sequence analysis and mutagenesis identify receptor binding epitopes
Jerva L, Lolis E, Sullivan G. Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: Sequence analysis and mutagenesis identify receptor binding epitopes. Protein Science 1997, 6: 1643-1652. PMID: 9260277, PMCID: PMC2143775, DOI: 10.1002/pro.5560060805.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntigens, CDBase SequenceCell LineChemokine CXCL2Chemokines, CXCCloning, MolecularDNA PrimersEpitopesHumansIntercellular Signaling Peptides and ProteinsMiceMolecular Sequence DataMonokinesMutagenesis, Site-DirectedNeutrophilsReceptors, InterleukinReceptors, Interleukin-8ARecombinant ProteinsSequence Homology, Amino Acid
1996
Structure-Function Studies of Murine MIP-2, the Homologue of Melanoma Growth Stimulating Activity/gro-α and IL-8
Lolis E, Jerva L. Structure-Function Studies of Murine MIP-2, the Homologue of Melanoma Growth Stimulating Activity/gro-α and IL-8. NATO ASI Series 1996, 183-194. DOI: 10.1007/978-3-642-61180-3_17.Peer-Reviewed Original ResearchHuman melanoma cellsProtein 2Structure-function studiesAnalysis of sequencesLigand-receptor complexesMurine MIP-2Melanoma cellsThree-dimensional structureMurine homologueGene productsAmino terminusMutational analysisInflammatory protein-2Molecular mechanismsIL-8MIP-2High affinityProteinAutocrine growth factorBinding profileHomologuesMetastatic potentialGrowth factorMelanoma growthType B receptors