2024
Hypothalamic hormone deficiency enables physiological anorexia in ground squirrels during hibernation
Mohr S, Dai Pra R, Platt M, Feketa V, Shanabrough M, Varela L, Kristant A, Cao H, Merriman D, Horvath T, Bagriantsev S, Gracheva E. Hypothalamic hormone deficiency enables physiological anorexia in ground squirrels during hibernation. Nature Communications 2024, 15: 5803. PMID: 38987241, PMCID: PMC11236985, DOI: 10.1038/s41467-024-49996-2.Peer-Reviewed Original ResearchConceptsHypothalamic feeding centersHormone deficiencyHypothalamic arcuate nucleus neuronsArcuate nucleus neuronsThyroid hormone deficiencyFeeding centerEffects of ghrelinAnorexigenic effectNucleus neuronsPhysiological anorexiaThyroid hormonesNormal physiological functionsGround squirrelsInterbout arousalAnorexiaThirteen-lined ground squirrelsProlonged periodReduced sensitivityPhysiological functionsDeficiency
2011
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature 2011, 476: 88-91. PMID: 21814281, PMCID: PMC3535012, DOI: 10.1038/nature10245.Peer-Reviewed Original ResearchConceptsVampire batsGene sequencesWarm-blooded preyGroup of snakesDifferent molecular mechanismsVertebrate lineageRNA splicingMolecular dataSensitive ion channelsMolecular mechanismsIon channelsBatsHeat-sensitive channelSplicingPit organsSnakesLineagesPreySequenceHot spotsDolphinsUnderliesRodentsVariants