2012
Real-time fMRI biofeedback targeting the orbitofrontal cortex for contamination anxiety.
Hampson M, Stoica T, Saksa J, Scheinost D, Qiu M, Bhawnani J, Pittenger C, Papademetris X, Constable T. Real-time fMRI biofeedback targeting the orbitofrontal cortex for contamination anxiety. Journal Of Visualized Experiments 2012 PMID: 22297729, PMCID: PMC3462579, DOI: 10.3791/3535.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyBiofeedback, PsychologyComputer SystemsFrontal LobeHumansMagnetic Resonance ImagingObsessive-Compulsive DisorderConceptsObsessive-compulsive disorderOrbitofrontal cortexBrain areasContamination anxietySymptom severityQuarter of patientsSpecific brain areasClinical improvementControl subjectsClinical changesMagnetic resonance imaging dataHealthy subjectsPsychiatric disordersTherapeutic interventionsFunctional magnetic resonance imaging (fMRI) dataBrain regionsObsessive-compulsive symptomsBrain functionTraining subjectsOCD symptom severityBiofeedback interventionConsistent findingCortexBiofeedback trainingBiofeedback
2011
Biofeedback of Real-Time Functional Magnetic Resonance Imaging Data from the Supplementary Motor Area Reduces Functional Connectivity to Subcortical Regions
Hampson M, Scheinost D, Qiu M, Bhawnani J, Lacadie CM, Leckman JF, Constable RT, Papademetris X. Biofeedback of Real-Time Functional Magnetic Resonance Imaging Data from the Supplementary Motor Area Reduces Functional Connectivity to Subcortical Regions. Brain Connectivity 2011, 1: 91-98. PMID: 22432958, PMCID: PMC3621512, DOI: 10.1089/brain.2011.0002.Peer-Reviewed Original ResearchConceptsSupplementary motor areaReal-time functional magnetic resonanceFunctional connectivityTourette syndromeFunctional magnetic resonanceMotor areaSubcortical regionsBiofeedback sessionsState functional connectivityTic symptomsMagnetic resonance imaging dataHealthy subjectsTS patientsMagnetic resonanceBrain areasBiofeedbackFunctional magnetic resonance imaging (fMRI) dataFurther studiesSignificant increaseAberrant dynamicsSubjectsRecent studiesImaging dataSessionsPatients