2023
Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes
Weber C, Lake E, Haider S, Mozayan A, Bobba P, Mukherjee P, Scheinost D, Constable R, Ment L, Payabvash S. Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes. Frontiers In Neuroscience 2023, 17: 1285396. PMID: 38075286, PMCID: PMC10702224, DOI: 10.3389/fnins.2023.1285396.Peer-Reviewed Original ResearchWhite matterPositive symptom correlationAutism spectrum disorderSymptom severity scoresBetween-group differencesAbnormal connectivity patternsCortical nodesVoxel-wise analysisDiffusion tensor imagingSeverity scoreWM fiber tractsSymptom correlationClinical dataConnectome disruptionConnectome changesEarly changesCortical regionsInfantsED reductionWM disruptionDisorder-specific changesTensor imagingFunctional imagingFiber tractsProbabilistic tractography
2009
DTI abnormalities in anterior corpus callosum of rats with spike–wave epilepsy
Chahboune H, Mishra AM, DeSalvo MN, Staib LH, Purcaro M, Scheinost D, Papademetris X, Fyson SJ, Lorincz ML, Crunelli V, Hyder F, Blumenfeld H. DTI abnormalities in anterior corpus callosum of rats with spike–wave epilepsy. NeuroImage 2009, 47: 459-466. PMID: 19398019, PMCID: PMC2712639, DOI: 10.1016/j.neuroimage.2009.04.060.Peer-Reviewed Original ResearchConceptsSpike-wave dischargesDiffusion tensor imagingAnterior corpus callosumWAG/RijFractional anisotropyWhite matter pathwaysSeizure activityAbsence epilepsyCorpus callosumDTI abnormalitiesEpileptic WAG/Rij ratsWAG/Rij ratsGenetic Absence Epilepsy RatsCallosal fractional anisotropySomatosensory cortex regionSpike-wave epilepsyBilateral spike-wave dischargesCommon seizure disorderWistar albino Glaxo ratsGlaxo ratsChronic seizuresEpileptic animalsNonepileptic controlsSeizure disorderNeurological difficulties