2014
Chapter 3 Prefrontal Limbic-Striatal Circuits and Alcohol Addiction in Humans
Seo D, Sinha R. Chapter 3 Prefrontal Limbic-Striatal Circuits and Alcohol Addiction in Humans. 2014, 49-63. DOI: 10.1016/b978-0-12-405941-2.00003-1.Peer-Reviewed Original Research
2013
Neural correlates of preparatory and regulatory control over positive and negative emotion
Seo D, Olman CA, Haut KM, Sinha R, MacDonald AW, Patrick CJ. Neural correlates of preparatory and regulatory control over positive and negative emotion. Social Cognitive And Affective Neuroscience 2013, 9: 494-504. PMID: 23887812, PMCID: PMC3989138, DOI: 10.1093/scan/nst115.Peer-Reviewed Original ResearchConceptsLateral prefrontal cortexEmotion regulationPrefrontal cortexGreater activationBrain activityCingulate cortexBilateral anterior prefrontal cortexRight lateral prefrontal cortexNegative emotion regulationActive emotion regulationCommon brain regionsAnterior prefrontal cortexVentromedial prefrontal cortexDorsomedial prefrontal cortexNegative emotional statesInferior parietal lobeFunctional magnetic resonanceBilateral dorsomedial prefrontal cortexPosterior cingulate cortexAnterior cingulate cortexMain effectRight precentral gyrusEmotional valencePositive emotionsNegative emotions
2011
Circulating glucose levels modulate neural control of desire for high-calorie foods in humans
Page KA, Seo D, Belfort-DeAguiar R, Lacadie C, Dzuira J, Naik S, Amarnath S, Constable RT, Sherwin RS, Sinha R. Circulating glucose levels modulate neural control of desire for high-calorie foods in humans. Journal Of Clinical Investigation 2011, 121: 4161-4169. PMID: 21926468, PMCID: PMC3195474, DOI: 10.1172/jci57873.Peer-Reviewed Original ResearchConceptsHigh-calorie foodsGlucose levelsHyperinsulinemic euglycemic-hypoglycemic clampsBrain regionsFunctional MRIMedial prefrontal cortexMedial prefrontal cortex activationRisk of overeatingLevels of glucosePostprandial reductionPrefrontal cortex activationObese subjectsNonobese individualsMild hypoglycemiaWorldwide epidemicCortex activationPrefrontal cortexFood cuesFood motivationFood stimuliNeural controlObesityInhibitory controlBehavioral measuresVisual cues
2008
Role of serotonin and dopamine system interactions in the neurobiology of impulsive aggression and its comorbidity with other clinical disorders
Seo D, Patrick CJ, Kennealy PJ. Role of serotonin and dopamine system interactions in the neurobiology of impulsive aggression and its comorbidity with other clinical disorders. Aggression And Violent Behavior 2008, 13: 383-395. PMID: 19802333, PMCID: PMC2612120, DOI: 10.1016/j.avb.2008.06.003.Peer-Reviewed Original ResearchImpulsive aggressionPrefrontal cortexComorbid disordersSubstance abuseDiathesis-stress modelVentral prefrontal cortexDeficient serotonergic functionRole of serotoninNeurobiological underpinningsUnderlying dispositionAggressive impulsesDysfunctional interactionsLife stressorsBiological diathesisFuture research directionsAggressionSerotonergic deficitsDopamine hyperfunctionSerotonergic deficiencySerotonergic functionDopamine dysregulationBrain imagingDopamine systemMental disordersClinical disorders