SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19
Tsatsakis A, Calina D, Falzone L, Petrakis D, Mitrut R, Siokas V, Pennisi M, Lanza G, Libra M, Doukas SG, Doukas PG, Kavali L, Bukhari A, Gadiparthi C, Vageli DP, Kofteridis DP, Spandidos DA, Paoliello MMB, Aschner M, Docea AO. SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19. Food And Chemical Toxicology 2020, 146: 111769. PMID: 32979398, PMCID: PMC7833750, DOI: 10.1016/j.fct.2020.111769.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeClinical symptomsLife-threatening acute respiratory distress syndromeCOVID-19SARS-CoV-2 infectionPeripheral neurological manifestationsSARS-CoV-2 pathophysiologyAcute respiratory distressRespiratory distress syndromeCOVID-19 infectionSpecific therapeutic managementSARS-CoV-2 virusSARS-CoV-2Present reviewPharmacotherapeutic managementGastrointestinal symptomsRenal dysfunctionDistress syndromeNeurological manifestationsRespiratory distressMild diseaseTherapeutic managementHealthy patientsCancer patientsCommon manifestation