1987
Substrate recognition and identification of splice sites by the tRNA-splicing endonuclease and ligase from Saccharomyces cerevisiae.
Greer C, Söll D, Willis I. Substrate recognition and identification of splice sites by the tRNA-splicing endonuclease and ligase from Saccharomyces cerevisiae. Molecular And Cellular Biology 1987, 7: 76-84. PMID: 3550427, PMCID: PMC365043, DOI: 10.1128/mcb.7.1.76.Peer-Reviewed Original Research
1985
Processing of precursor tRNAs in Drosophila. Processing of the 3‘ end involves an endonucleolytic cleavage and occurs after 5‘ end maturation.
Frendewey D, Dingermann T, Cooley L, Söll D. Processing of precursor tRNAs in Drosophila. Processing of the 3‘ end involves an endonucleolytic cleavage and occurs after 5‘ end maturation. Journal Of Biological Chemistry 1985, 260: 449-454. PMID: 3843841, DOI: 10.1016/s0021-9258(18)89752-6.Peer-Reviewed Original Research
1984
Mutations affecting excision of the intron from a eukaryotic dimeric tRNA precursor.
Willis I, Hottinger H, Pearson D, Chisholm V, Leupold U, Söll D. Mutations affecting excision of the intron from a eukaryotic dimeric tRNA precursor. The EMBO Journal 1984, 3: 1573-1580. PMID: 6430697, PMCID: PMC557561, DOI: 10.1002/j.1460-2075.1984.tb02013.x.Peer-Reviewed Original ResearchMeSH KeywordsAscomycotaBase SequenceGenesMutationNucleic Acid ConformationNucleic Acid PrecursorsRNA Processing, Post-TranscriptionalRNA, TransferSchizosaccharomycesSerineConceptsTRNA precursorsDimeric tRNA precursorSerine tRNA geneEfficiency of splicingPrecursor tRNA processingSingle base changeTRNA genesTRNASer geneTRNA processingGene transcriptionNucleotide sequenceUGA mutationsD-loopMutant geneGenesBase changesExtra armMutationsIntronsTranscriptionVivo systemDimeric precursorSequenceTRNASerSplicing
1980
Dimeric tRNA precursors in yeast
Schmidt O, Mao J, Ogden R, Beckmann J, Sakano H, Abelson J, Söll D. Dimeric tRNA precursors in yeast. Nature 1980, 287: 750-752. PMID: 6253814, DOI: 10.1038/287750a0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceEndonucleasesGenesNucleic Acid PrecursorsRNA, TransferSaccharomyces cerevisiaeTranscription, GeneticXenopus laevisConceptsDimeric tRNA precursorTRNA precursorsDNA fragmentsYeast tRNA genesDifferent genomic regionsNucleotide sequence analysisTRNA genesSaccharomyces cerevisiae1Xenopus nucleiGenomic regionsSpecific transcriptionTRNA speciesPrecursor RNARNA precursorsTRNA moleculesGene regionSequence analysisGene configurationEnzyme activityGenesMode of expressionFragmentsTranscriptionYeastTRNAAspDimeric transfer RNA precursors in S. pombe
Mao J, Schmidt O, Söll D. Dimeric transfer RNA precursors in S. pombe. Cell 1980, 21: 509-516. PMID: 7407924, DOI: 10.1016/0092-8674(80)90488-2.Peer-Reviewed Original ResearchMeSH KeywordsAscomycotaBase SequenceCloning, MolecularGenesNucleic Acid PrecursorsRNA, FungalRNA, TransferSchizosaccharomycesTranscription, GeneticConceptsTRNA genesNucleotide intronRNA precursorsDNA fragmentsNuclear extractsNucleotide spacerPrimary transcription productTransfer RNA precursorsNucleotide leader sequenceS. pombeTRNA sequencesTrailer sequencesRNA initiationLeader sequenceTRNA moleculesTranscription productsEnzymatic stepsSequence analysisRNA analysisXenopus oocytesGenesEndonuclease cleavageIntronsTerminusSequence
1979
In vitro transcription and processing of a yeast tRNA gene containing an intervening sequence
Ogden R, Beckman J, Abelson J, Kang H, Söll D, Schmidt O. In vitro transcription and processing of a yeast tRNA gene containing an intervening sequence. Cell 1979, 17: 399-406. PMID: 378410, DOI: 10.1016/0092-8674(79)90166-1.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell NucleusCell-Free SystemFemaleGenesNucleic Acid PrecursorsOocytesRNA, TransferSaccharomyces cerevisiaeTranscription, GeneticXenopusConceptsTRNATrp gene
1978
Specific transcription of eukaryotic tRNA genes in Xenopus germinal vesicle extracts.
Schmidt O, Mao J, Silverman S, Hovemann B, Söll D. Specific transcription of eukaryotic tRNA genes in Xenopus germinal vesicle extracts. Proceedings Of The National Academy Of Sciences Of The United States Of America 1978, 75: 4819-4823. PMID: 105357, PMCID: PMC336212, DOI: 10.1073/pnas.75.10.4819.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell NucleusDNA, RecombinantDrosophila melanogasterFemaleNucleic Acid PrecursorsOocytesRNA, TransferTranscription, GeneticXenopusConceptsGerminal vesicle extractsTRNA genesRNA speciesVesicle extractsEukaryotic gene transcriptionEukaryotic tRNA genesRegulatory DNA regionsPrecursor tRNA moleculesXenopus germinal vesiclePrecursor tRNAsSpecific transcriptionDNA regionsTRNA biosynthesisTRNA precursorsNucleotide modificationsGene transcriptionTRNA moleculesTranscription systemNucleotide analysisTRNAGerminal vesicleGenesTranscriptionTRNALysSpecies