2011
An unusual tRNAThr derived from tRNAHis reassigns in yeast mitochondria the CUN codons to threonine
Su D, Lieberman A, Lang BF, Simonović M, Söll D, Ling J. An unusual tRNAThr derived from tRNAHis reassigns in yeast mitochondria the CUN codons to threonine. Nucleic Acids Research 2011, 39: 4866-4874. PMID: 21321019, PMCID: PMC3113583, DOI: 10.1093/nar/gkr073.Peer-Reviewed Original ResearchConceptsCUN codonsYeast mitochondriaGenetic codeAlloacceptor tRNA gene recruitmentComprehensive phylogenetic analysisStandard genetic codeThreonyl-tRNA synthetaseHistidyl-tRNA synthetaseGene recruitmentEvolutionary originPhylogenetic analysisRecoding eventBiochemical experimentsFirst nucleotideAnticodon loopMST1CodonFirst clear exampleYeastMitochondriaThreonineSynthetaseCandida albicansGenomeClear example
2004
Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem?
Ambrogelly A, Kamtekar S, Sauerwald A, Ruan B, Tumbula-Hansen D, Kennedy D, Ahel I, Söll D. Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem? Cellular And Molecular Life Sciences 2004, 61: 2437-2445. PMID: 15526152, DOI: 10.1007/s00018-004-4194-9.Peer-Reviewed Original ResearchConceptsMethanogenic archaeaCysteine biosynthesisCellular translation machineryAminoacyl-tRNA synthesisCanonical cysteinyl-tRNA synthetaseAminoacyl-tRNA synthetasesCysteinyl-tRNA synthetaseRecognizable genesTranslation machineryGenome sequenceArchaeaBiosynthesisEssential componentSynthetasesTRNARibosomesGenesMachineryOrganismsSynthetasePossible linkSequenceFormation
1996
Protein-RNA molecular recognition
Ibba M, Söll D. Protein-RNA molecular recognition. Nature 1996, 381: 656-656. PMID: 8649510, DOI: 10.1038/381656a0.Peer-Reviewed Original Research
1993
Molecular analysis of three maize 22 kDa auxin‐binding protein genes — transient promoter expression and regulatory regions
Schwob E, Choi S, Simmons C, Migliaccio F, Ilag L, Hesse T, Palme K, Söll D. Molecular analysis of three maize 22 kDa auxin‐binding protein genes — transient promoter expression and regulatory regions. The Plant Journal 1993, 4: 423-432. PMID: 7693132, DOI: 10.1046/j.1365-313x.1993.04030423.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceDNA, ComplementaryGene ExpressionGenes, PlantGenes, RegulatorGenes, ReporterIndoleacetic AcidsMolecular Sequence DataPlant Growth RegulatorsPlant ProteinsPromoter Regions, GeneticReceptors, Cell SurfaceRestriction MappingRNASequence DeletionSequence Homology, Amino AcidSequence Homology, Nucleic AcidTissue DistributionZea maysConceptsZm-ERabp1C-terminal KDEL sequenceSmall gene familyMolecular analysisPromoter deletion analysisMaize leaf protoplastsAuxin-binding proteinGene expression systemNegative regulatory sequencesPrimer extension analysisAuxin-binding siteGene-specific oligonucleotide probesTwofold higher expressionTransit peptideGene familySignal peptideLeaf protoplastsRegulatory sequencesTranscription startDeletion analysisTranscription factorsRegulatory regionsTATA boxKDEL sequencePromoter expression
1991
Mono Q chromatography permits recycling of DNA template and purification of RNA transcripts after T7 RNA polymerase reaction
Jahn M, Jahn D, Kumar A, Söll D. Mono Q chromatography permits recycling of DNA template and purification of RNA transcripts after T7 RNA polymerase reaction. Nucleic Acids Research 1991, 19: 2786-2786. PMID: 1710347, PMCID: PMC328209, DOI: 10.1093/nar/19.10.2786.Peer-Reviewed Original Research
1984
Developmentally regulated plant genes: the nucleotide sequence of a wheat gliadin genomic clone.
Rafalski J, Scheets K, Metzler M, Peterson D, Hedgcoth C, Söll D. Developmentally regulated plant genes: the nucleotide sequence of a wheat gliadin genomic clone. The EMBO Journal 1984, 3: 1409-1415. PMID: 6204862, PMCID: PMC557531, DOI: 10.1002/j.1460-2075.1984.tb01985.x.Peer-Reviewed Original ResearchConceptsCDNA clonesGenomic clonesWheat genomic libraryWheat seed storage proteinsInternal sequence repetitionSeed storage proteinsSuch genomic clonesTranslation termination codonEukaryotic promoter sequencesPlant genesNorthern blot analysisMultigene familyGliadin genesGenomic libraryHybrid-selected mRNA translationMRNA translationCDNA sequenceGene sequencesPromoter sequencesCDNA libraryStorage proteinsDNA sequencesNucleotide sequenceNumber of clonesTermination codon
1983
Partial purification of Drosophila Kc cell RNA polymerase III transcription components. Evidence for shared 5 S RNA and tRNA gene factors.
Burke D, Schaack J, Sharp S, Söll D. Partial purification of Drosophila Kc cell RNA polymerase III transcription components. Evidence for shared 5 S RNA and tRNA gene factors. Journal Of Biological Chemistry 1983, 258: 15224-15231. PMID: 6197413, DOI: 10.1016/s0021-9258(17)43797-5.Peer-Reviewed Original ResearchConceptsS RNA geneTranscription componentsRNA polymerase IIIRNA genesPolymerase IIIStable transcription complex formationReconstitution of transcriptionTranscription complex formationDrosophila Kc cellsCM-Sepharose column chromatographyDrosophila tRNAKc cellsTranscription factorsS RNATRNAGene factorsCompetition experimentsTranscriptionGenesComplex formationPartial purificationDEAE-SephadexReconstitutionCofractionationColumn chromatography
1981
Transcription of cloned tRNA and 5S RNA genes in a Drosophila cell free extract
Dingermann T, Sharp S, Appel B, DeFranco D, Mount S, Heiermann R, Pongs O, Söll D. Transcription of cloned tRNA and 5S RNA genes in a Drosophila cell free extract. Nucleic Acids Research 1981, 9: 3907-3918. PMID: 6170932, PMCID: PMC327404, DOI: 10.1093/nar/9.16.3907.Peer-Reviewed Original ResearchA conversational system for the computer analysis of nucleic acid sequences
Sege R, Söll D, Ruddle F, Queen C. A conversational system for the computer analysis of nucleic acid sequences. Nucleic Acids Research 1981, 9: 437-444. PMID: 6163137, PMCID: PMC326703, DOI: 10.1093/nar/9.2.437.Peer-Reviewed Original Research
1974
New aspects in tRNA biosynthesis
Schäfer K, Söll D. New aspects in tRNA biosynthesis. Biochimie 1974, 56: 795-804. PMID: 4614860, DOI: 10.1016/s0300-9084(74)80500-6.Peer-Reviewed Original ResearchFingerprinting nonradioactive ribonucleic acid with the aid of polynucleotide phosphorylase
Szeto K, Söll D. Fingerprinting nonradioactive ribonucleic acid with the aid of polynucleotide phosphorylase. Nucleic Acids Research 1974, 1: 171-182. PMID: 10793669, PMCID: PMC343333, DOI: 10.1093/nar/1.1.171.Peer-Reviewed Original Research