1989
Multiple Mutations of the First Gene of a Dimeric tRNA Gene Abolish in Vitro tRNA Gene Transcription
Nichols M, Bell J, Klekamp M, Weil P, Söll D. Multiple Mutations of the First Gene of a Dimeric tRNA Gene Abolish in Vitro tRNA Gene Transcription. Journal Of Biological Chemistry 1989, 264: 17084-17090. PMID: 2676999, DOI: 10.1016/s0021-9258(18)71462-2.Peer-Reviewed Original ResearchMeSH KeywordsCloning, MolecularEndopeptidasesMutationPromoter Regions, GeneticRegulatory Sequences, Nucleic AcidRNA Polymerase IIIRNA, FungalRNA, TransferRNA, Transfer, MetRNA, Transfer, SerSaccharomyces cerevisiaeSchizosaccharomycesTranscription Factor TFIIIBTranscription FactorsTranscription Factors, TFIIITranscription, GeneticConceptsMethionine tRNA geneTRNA genesGene transcriptionInitiator methionine tRNA geneRNA polymerase III systemRNA polymerase III transcriptionMutant tRNA genesTRNA gene transcriptionAdditional protein factorsSerine tRNA genePolymerase III transcriptionRNA polymerase IIIICR sequenceTranscription regulationTRNA locusFirst geneExpression initiatesProtein factorsTranscription studiesPolymerase IIINucleotides 8Gene promoterDetectable transcriptsTranscriptionGenes
1982
Eukaryotic tRNA gene transcription is controlled by signals within and outside the mature coding sequence.
DeFranco D, Dingermann T, Johnson D, Sharp S, Söll D. Eukaryotic tRNA gene transcription is controlled by signals within and outside the mature coding sequence. Princess Takamatsu Symposia 1982, 12: 63-72. PMID: 7166550.Peer-Reviewed Original ResearchConceptsTRNA genesMature coding sequenceTranscriptional repressionTRNA sequencesControl regionCoding sequenceEukaryotic tRNA gene transcriptionDrosophila tRNAArg geneSecond control regionEukaryotic tRNA genesDrosophila tRNA genesTRNA gene transcriptionMature tRNA sequencesInitiation of transcriptionNuclease Bal 31TRNAArg geneMature tRNAPoor transcriptional activityDeletion analysisGene transcriptionNucleotides 8D-loopTranscriptional activityPromoter regionBAL-31