2002
Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia.
Saravia NG, Weigle K, Navas C, Segura I, Valderrama L, Valencia AZ, Escorcia B, McMahon-Pratt D. Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia. American Journal Of Tropical Medicine And Hygiene 2002, 66: 738-44. PMID: 12224583, DOI: 10.4269/ajtmh.2002.66.738.Peer-Reviewed Original Research
1998
T cell responses to crude and defined leishmanial antigens in patients from the Lower Amazon region of Brazil infected with different species of Leishmania of the subgenera Leishmania and Viannia
Silveira F, Blackwell J, Ishikawa E, Braga R, Shaw J, Quinnell R, Soong L, Kima P, McMahon‐Pratt D, Black G, Shaw M. T cell responses to crude and defined leishmanial antigens in patients from the Lower Amazon region of Brazil infected with different species of Leishmania of the subgenera Leishmania and Viannia. Parasite Immunology 1998, 20: 19-26. PMID: 9491414, DOI: 10.1046/j.1365-3024.1998.t01-1-00126.x.Peer-Reviewed Original ResearchConceptsT cell responsesDiffuse cutaneous leishmaniasisLeishmanial antigensCell responsesLCL patientsMucocutaneous leishmaniasisMCL patientsCutaneous leishmaniasisL. amazonensis antigensSkin test responsesL. braziliensis antigensSuitable vaccine candidateDCL patientsPoor respondersGood respondersPatient groupBraziliensis antigensSubgenus LeishmaniaAntigen A2Vaccine candidatesPatientsPotent stimulatorA2 antigenAntigenSignificant rise
1993
Developmental Life Cycle of Leishmania—Cultivation and Characterization of Cultured Extracellular Amastigotes1
PAN A, DUBOISE S, EPERON S, RIVAS L, HODGKINSON V, TRAUB‐CSEKO Y, MCMAHON‐PRATT D. Developmental Life Cycle of Leishmania—Cultivation and Characterization of Cultured Extracellular Amastigotes1. Journal Of Eukaryotic Microbiology 1993, 40: 213-223. PMID: 8461895, DOI: 10.1111/j.1550-7408.1993.tb04906.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdaptation, PhysiologicalAnimalsAntibodies, MonoclonalGerm-Free LifeLeishmaniaSpecies SpecificityConceptsPlethora of proteinsCultured amastigotesDevelopmental life cycleDevelopmental responsesDevelopmental regulationAxenic cultureAxenic linesAmastigote stageBiochemical evidenceLife cycleInfected macrophagesOrganismsEnvironmental parametersLeishmania promastigotesAmastigotesDevelopmental investigationsLeishmaniaProteinParasitesRegulationBiochemistryLinesLeishmania amastigotesCharacterizationLeishmania organisms
1990
Production of a specific monoclonal antibody for the identification of Leishmania (Leishmania) venezuelensis.
Hanham C, Shaw J, Lainson R, McMahon-Pratt D. Production of a specific monoclonal antibody for the identification of Leishmania (Leishmania) venezuelensis. American Journal Of Tropical Medicine And Hygiene 1990, 42: 453-9. PMID: 2187366, DOI: 10.4269/ajtmh.1990.42.453.Peer-Reviewed Original Research
1989
Extracellular Amastigote‐Like Forms of Leishmania panamensis and L. braziliensis. II. Stage‐ and Species‐Specific Monoclonal Antibodies
EPERON S, McMAHON‐PRATT D. Extracellular Amastigote‐Like Forms of Leishmania panamensis and L. braziliensis. II. Stage‐ and Species‐Specific Monoclonal Antibodies. Journal Of Eukaryotic Microbiology 1989, 36: 510-518. PMID: 2478699, DOI: 10.1111/j.1550-7408.1989.tb01087.x.Peer-Reviewed Original ResearchAmastigote and epimastigote stage-specific components of Trypanosoma cruzi characterized by using monoclonal antibodies. Purification and molecular characterization of an 83-kilodalton amastigote protein.
Pan A, McMahon-Pratt D. Amastigote and epimastigote stage-specific components of Trypanosoma cruzi characterized by using monoclonal antibodies. Purification and molecular characterization of an 83-kilodalton amastigote protein. The Journal Of Immunology 1989, 143: 1001-8. PMID: 2501384, DOI: 10.4049/jimmunol.143.3.1001.Peer-Reviewed Original ResearchConceptsTissue culture-derived trypomastigotesTrypanosoma cruziCruzi amastigotesPreliminary sequence dataStage-specific componentsCulture-derived trypomastigotesStage-specific monoclonal antibodiesSingle protein moleculesMembrane-enriched preparationsAmino acid compositionSequence dataEpimastigote membranesHuman chagasic seraStage differentiationAxenic cultureMolecular characterizationT. cruzi amastigotesEpimastigotesProtein moleculesProteinChagas diseaseMonoclonal antibodiesLeishmania speciesAcid compositionChagasic sera
1988
The identification of membrane glycoconjugates in Leishmania species.
Jaffe C, McMahon-Pratt D. The identification of membrane glycoconjugates in Leishmania species. Journal Of Parasitology 1988, 74: 548-61. PMID: 3397816, DOI: 10.2307/3282170.Peer-Reviewed Original ResearchMonoclonal antibodies specific for the amastigote stage of Leishmania pifanoi. I. Characterization of antigens associated with stage- and species-specific determinants.
Pan A, McMahon-Pratt D. Monoclonal antibodies specific for the amastigote stage of Leishmania pifanoi. I. Characterization of antigens associated with stage- and species-specific determinants. The Journal Of Immunology 1988, 140: 2406-14. PMID: 2450920, DOI: 10.4049/jimmunol.140.7.2406.Peer-Reviewed Original Research
1987
Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies
Jaffe C, McMahon-Pratt D. Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 1987, 81: 587-594. PMID: 3445339, DOI: 10.1016/0035-9203(87)90418-4.Peer-Reviewed Original ResearchConceptsVisceral leishmaniasisMonoclonal antibodiesSerodiagnostic assaysVL seraParasite antigensChagas diseaseSystemic lupus erythematosusNon-endemic areasDifferent parasite antigensLeishmania antigenLupus erythematosusMucocutaneous leishmaniasisLepromatous leprosyNegative control seraPositive casesSpecies-specific monoclonal antibodiesNormal serumControl seraRapid diagnosisAntigenSerum dilutionSerumAntibodiesLeishmaniasisSpecific inhibition
1985
Brazilian Leishmania stocks phenotypically similar to Leishmania major.
Pacheco R, Jaffe C, Grimaldi G, Marzochi M, McMahon-Pratt D, Momen H. Brazilian Leishmania stocks phenotypically similar to Leishmania major. American Journal Of Tropical Medicine And Hygiene 1985, 34: 1076-84. PMID: 3834794, DOI: 10.4269/ajtmh.1985.34.1076.Peer-Reviewed Original ResearchConceptsEnzyme profilesEnzyme electrophoresisL. mexicanaRestriction enzyme profilesL. donovani speciesIndirect radioimmuneNew World LeishmaniaL. braziliensisSchizodeme analysisL. majorMonoclonal antibodiesCutaneous speciesReference strainsSpeciesDifferent geographic areasMexicanaL. donovaniElectrophoresisLeishmaniaLarge panelSubspeciesBspRIMspIBraziliensisGeographic areas
1984
Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis.
Jaffe C, Bennett E, Grimaldi G, McMahon-Pratt D. Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis. The Journal Of Immunology 1984, 133: 440-7. PMID: 6373932, DOI: 10.4049/jimmunol.133.1.440.Peer-Reviewed Original ResearchConceptsMonoclonal antibodiesVisceral leishmaniasisSpecies-specific monoclonal antibodiesL. donovaniAntibody DAntigenic determinantsLeishmania donovaniKala-azar serumWestern blot analysisSpecies of LeishmaniaSerologic assaysEpidemiologic studiesClinical diagnosisWestern blotAntigenic moleculesProtein antigensRadioimmunoprecipitation analysisAntibodiesLeishmaniasisLeishmania speciesLeishmania stocksDonovaniMonoclonal antibody DBlot analysisAntigen
1983
Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants.
Jaffe C, McMahon-Pratt D. Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants. The Journal Of Immunology 1983, 131: 1987-93. PMID: 6194223, DOI: 10.4049/jimmunol.131.4.1987.Peer-Reviewed Original ResearchConceptsSpecies-specific determinantsPromastigote stageDifferent cell surface proteinsCell surface proteinsMonoclonal antibody bindsMembrane-enriched preparationsCell surface componentsL. tropica complexAdditional proteinsKilodalton proteinClone TTrypanosoma cruziSurface proteinsProteinMonoclonal antibodiesIntact promastigotesSurface componentsSolubilized 125IL. donovaniL. braziliensis braziliensisMajor promastigotesL. mexicana amazonensisPromastigotesI. CharacterizationCruzi
1982
Monoclonal antibodies that distinguish subspecies of Leishmania braziliensis.
McMahon-Pratt D, Bennett E, David J. Monoclonal antibodies that distinguish subspecies of Leishmania braziliensis. The Journal Of Immunology 1982, 129: 926-7. PMID: 7108210, DOI: 10.4049/jimmunol.129.3.926.Peer-Reviewed Original Research