2010
Megasomes in Leishmania
McMahon-Pratt D, Ueda-Nakamura T, Traub-Csekö Y. Megasomes in Leishmania. Microbiology Monographs 2010, 17: 131-148. DOI: 10.1007/978-3-642-12863-9_6.Peer-Reviewed Original ResearchImportance of lysosomesProtein traffickingLeishmania virulenceResident enzymesMammalian hostsLysosome-like structuresLeishmania mexicana complexParasite existLysosomal hydrolasesTargeting mechanismCysteine proteinasesSerious public health problemPublic health problemMexicana complexPhlebotomine sandfliesLesion amastigotesGenus LeishmaniaAmastigote formsGood targetClassic pathwayPathwayPromastigote formsHealth problemsMegasomesInsects
1991
Biochemical and molecular characterization ofLeishmania pifanoi amastigotes in continuous axenic culture
Rainey P, Spithill T, McMahon-Pratt D, Pan A. Biochemical and molecular characterization ofLeishmania pifanoi amastigotes in continuous axenic culture. Molecular And Biochemical Parasitology 1991, 49: 111-118. PMID: 1775152, DOI: 10.1016/0166-6851(91)90134-r.Peer-Reviewed Original ResearchConceptsContinuous axenic cultureSynthesis of DNAMolecular geneticsAdenine deaminaseAmastigote-like formsAxenic cultureAxenic mediumExcellent modelAxenic formsLeishmania pifanoiMetabolism of glucosePeroxidase activityAmastigote formsPromastigote formsAmastigotesCulture formsGenesGeneticsRNAProteinDNAReductaseRibonucleaseLinoleic acidPrevious demonstration