2014
Chronicity of Dermal Leishmaniasis Caused by Leishmania panamensis Is Associated with Parasite-Mediated Induction of Chemokine Gene Expression
Navas A, Vargas DA, Freudzon M, McMahon-Pratt D, Saravia NG, Gómez MA. Chronicity of Dermal Leishmaniasis Caused by Leishmania panamensis Is Associated with Parasite-Mediated Induction of Chemokine Gene Expression. Infection And Immunity 2014, 82: 2872-2880. PMID: 24752514, PMCID: PMC4097649, DOI: 10.1128/iai.01133-13.Peer-Reviewed Original ResearchConceptsSelf-healed patientsChronic cutaneous leishmaniasisDermal leishmaniasisChemokine gene expressionClinical outcomesBiopsy specimensChronic diseasesInflammatory responseLeishmania panamensisExpression levelsCCR5 receptor geneInduction of CXCL5Montenegro skin testLesion biopsy specimensL. panamensisSelf-healing diseaseNew therapeutic targetsReverse transcription-quantitative PCRTranscription-quantitative PCRChemotactic chemokinesInflammation contributesSkin testAsymptomatic infectionInflammatory activationImmune cells
1991
Leishmania donovani chagasi: new clinical variant of cutaneous leishmaniasis in Honduras
Ponce C, Ponce E, Morrison A, Cruz A, Kreutzer R, McMahon-Pratt D, Neva F. Leishmania donovani chagasi: new clinical variant of cutaneous leishmaniasis in Honduras. The Lancet 1991, 337: 67-70. PMID: 1670724, DOI: 10.1016/0140-6736(91)90734-7.Peer-Reviewed Original ResearchConceptsCutaneous leishmaniasisSkin lesionsEndemic visceral leishmaniasisMontenegro skin testNew clinical variantAtypical cutaneous leishmaniasisSkin testLaboratory criteriaClinical variantsVisceral leishmaniasisKala-azarBone marrowPatientsParasite isolatesLesionsMajor antigenLeishmaniasisLeishmania mexicanaUnusual formIsoenzyme analysisYearsMarrowAntigenChagasiMonths