1988
Intracellular signaling transduction in the differentiation of Trypanosoma cruzi: role of cAMP.
Rangel-Aldao R, Triana F, Comach G, Abate T, Fernández V, McMahon-Pratt D. Intracellular signaling transduction in the differentiation of Trypanosoma cruzi: role of cAMP. Biological Research 1988, 21: 403-8. PMID: 2855697.Peer-Reviewed Original ResearchConceptsCell differentiationCAMP-dependent protein kinaseTrypanosoma cruziTypes of proteinsTransformation of epimastigotesProtein kinaseMetacyclic trypomastigotesRole of cAMPIntracellular cAMP levelsT. cruziReceptor proteinEpimastigotesCruziDifferentiationMajor bandProteinCAMP levelsPolyclonal antibodiesSpecific activityRII antibodyCrude homogenatesTransductionKinaseCAMPNovel type
1983
Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants.
Jaffe C, McMahon-Pratt D. Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants. The Journal Of Immunology 1983, 131: 1987-93. PMID: 6194223, DOI: 10.4049/jimmunol.131.4.1987.Peer-Reviewed Original ResearchConceptsSpecies-specific determinantsPromastigote stageDifferent cell surface proteinsCell surface proteinsMonoclonal antibody bindsMembrane-enriched preparationsCell surface componentsL. tropica complexAdditional proteinsKilodalton proteinClone TTrypanosoma cruziSurface proteinsProteinMonoclonal antibodiesIntact promastigotesSurface componentsSolubilized 125IL. donovaniL. braziliensis braziliensisMajor promastigotesL. mexicana amazonensisPromastigotesI. CharacterizationCruzi