2002
Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia.
Saravia NG, Weigle K, Navas C, Segura I, Valderrama L, Valencia AZ, Escorcia B, McMahon-Pratt D. Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia. American Journal Of Tropical Medicine And Hygiene 2002, 66: 738-44. PMID: 12224583, DOI: 10.4269/ajtmh.2002.66.738.Peer-Reviewed Original Research
2000
Molecular and biologic characterization of Leishmania parasites implicated in an epidemic outbreak in northwestern Argentina
Segura E, Juan N, Piquin A, Cuba Cuba C, Abramo Orrego L, McMahon-Pratt D, Montamat E, Momen H, Grimaldi Jr. G. Molecular and biologic characterization of Leishmania parasites implicated in an epidemic outbreak in northwestern Argentina. Parasitology Research 2000, 86: 504-508. PMID: 10894479, DOI: 10.1007/s004360050702.Peer-Reviewed Original ResearchInternalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis
Kima P, Constant S, Hannum L, Colmenares M, Lee K, Haberman A, Shlomchik M, McMahon-Pratt D. Internalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis. Journal Of Experimental Medicine 2000, 191: 1063-1068. PMID: 10727468, PMCID: PMC2193117, DOI: 10.1084/jem.191.6.1063.Peer-Reviewed Original ResearchConceptsFc receptorsB cell antigen presentationMurine cutaneous leishmaniasisFunctional B cellsCommon gamma chainL. mexicana complexLeishmania infectionAntigen presentationCutaneous leishmaniasisB cellsLeishmania pathogenesisInfectionComplex parasitesCritical roleAntibodiesMexicana complexPathogenesisMiceGamma chainReceptorsParasitesLeishmaniasis
1997
Characterization of Endotrypanum Parasites Using Specific Monoclonal Antibodies
Franco A, MC Machado G, Naiff R, Moreira C, McMahon-Pratt D, Grimaldi G. Characterization of Endotrypanum Parasites Using Specific Monoclonal Antibodies. Memórias Do Instituto Oswaldo Cruz 1997, 92: 63-68. DOI: 10.1590/s0074-02761997000100013.Peer-Reviewed Original ResearchMonoclonal antibodiesNumber of mAbsWestern blot analysisSpecific monoclonal antibodiesImmunological assay systemsEpitope densityAntigenic determinantsAntigenic groupsMAbsAntigenic diversityBlot analysisELISAAntibodiesImmunofluorescenceAssay systemParasitesE. schaudinniClone EMolecular formsGeographic areasLatter parasiteReactivity patternsL. equatorensis
1991
Biochemical characterization of the protective membrane glycoprotein GP46/M-2 of Leishmania amazonensis
Rivas L, Kahl L, Manson K, McMahon-Pratt D. Biochemical characterization of the protective membrane glycoprotein GP46/M-2 of Leishmania amazonensis. Molecular And Biochemical Parasitology 1991, 47: 235-243. PMID: 1719417, DOI: 10.1016/0166-6851(91)90183-7.Peer-Reviewed Original ResearchConceptsGP46/MCarbohydrate side chainsDNA-derived protein sequenceLipid anchorSpecies-specific epitopesProtein sequencesSide chainsBiochemical characterizationLeishmania amazonensisProteinBiochemical featuresPolypeptide portionSurface membraneMonoclonal antibodiesPolypeptideAmazonensisMoleculesEpitopesAnchorsSequenceMembraneDigestionAntibodiesChainPromastigotes
1989
Monoclonal Antibodies Specific for Members of the Genus Endotrypanum
LOPES A, McMAHON‐PRATT D. Monoclonal Antibodies Specific for Members of the Genus Endotrypanum. Journal Of Eukaryotic Microbiology 1989, 36: 354-361. PMID: 2504911, DOI: 10.1111/j.1550-7408.1989.tb05526.x.Peer-Reviewed Original ResearchIdentification, using isoenzyme electrophoresis and monoclonal antibodies, of Leishmania isolated from humans and wild animals of Ecuador.
Mimori T, Grimaldi G, Kreutzer R, Gomez E, McMahon-Pratt D, Tesh R, Hashiguchi Y. Identification, using isoenzyme electrophoresis and monoclonal antibodies, of Leishmania isolated from humans and wild animals of Ecuador. American Journal Of Tropical Medicine And Hygiene 1989, 40: 154-8. PMID: 2919726, DOI: 10.4269/ajtmh.1989.40.154.Peer-Reviewed Original Research
1988
Purification and characterization of an 80-kilodalton membrane protein from Leishmania donovani
White A, McMahon-Pratt D. Purification and characterization of an 80-kilodalton membrane protein from Leishmania donovani. Infection And Immunity 1988, 56: 2385-2391. PMID: 3165961, PMCID: PMC259577, DOI: 10.1128/iai.56.9.2385-2391.1988.Peer-Reviewed Original Research
1987
Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies
Jaffe C, McMahon-Pratt D. Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 1987, 81: 587-594. PMID: 3445339, DOI: 10.1016/0035-9203(87)90418-4.Peer-Reviewed Original ResearchConceptsVisceral leishmaniasisMonoclonal antibodiesSerodiagnostic assaysVL seraParasite antigensChagas diseaseSystemic lupus erythematosusNon-endemic areasDifferent parasite antigensLeishmania antigenLupus erythematosusMucocutaneous leishmaniasisLepromatous leprosyNegative control seraPositive casesSpecies-specific monoclonal antibodiesNormal serumControl seraRapid diagnosisAntigenSerum dilutionSerumAntibodiesLeishmaniasisSpecific inhibitionLeishmaniasis in Brazil: XXIII. The identification of Leishmania braziliensis braziliensis in wild-caught neotropical sandflies using monoclonal antibodies
Shaw J, Lainson R, Ryan L, Braga R, McMahon-Pratt D, David J. Leishmaniasis in Brazil: XXIII. The identification of Leishmania braziliensis braziliensis in wild-caught neotropical sandflies using monoclonal antibodies. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 1987, 81: 69-72. PMID: 3445325, DOI: 10.1016/0035-9203(87)90287-2.Peer-Reviewed Original Research
1984
Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis.
Jaffe C, Bennett E, Grimaldi G, McMahon-Pratt D. Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis. The Journal Of Immunology 1984, 133: 440-7. PMID: 6373932, DOI: 10.4049/jimmunol.133.1.440.Peer-Reviewed Original ResearchConceptsMonoclonal antibodiesVisceral leishmaniasisSpecies-specific monoclonal antibodiesL. donovaniAntibody DAntigenic determinantsLeishmania donovaniKala-azar serumWestern blot analysisSpecies of LeishmaniaSerologic assaysEpidemiologic studiesClinical diagnosisWestern blotAntigenic moleculesProtein antigensRadioimmunoprecipitation analysisAntibodiesLeishmaniasisLeishmania speciesLeishmania stocksDonovaniMonoclonal antibody DBlot analysisAntigen