2016
Therapeutic Challenges of Hepatic Mucormycosis in Hematologic Malignancy: A Case Report and Review of the Literature
Bernardo RM, Gurung A, Jain D, Malinis MF. Therapeutic Challenges of Hepatic Mucormycosis in Hematologic Malignancy: A Case Report and Review of the Literature. American Journal Of Case Reports 2016, 17: 484-489. PMID: 27406045, PMCID: PMC4948661, DOI: 10.12659/ajcr.898480.Peer-Reviewed Case Reports and Technical NotesConceptsDual antifungal therapyAntifungal therapyHepatic mucormycosisSurgical resectionClinical presentationCase reportLiver lesionsIsolated hepatic mucormycosisTransplant-associated infectionsMultiple liver lesionsCombination antifungal therapyAcute myeloid leukemiaHigh mortality rateOptimal antifungal therapyGastrointestinal involvementInduction chemotherapyNeutropenic feverAbdominal painLymphoproliferative disordersTherapeutic challengeHematologic malignanciesCommon siteMyeloid leukemiaTreatment strategiesGastrointestinal tract
2014
Individual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology
Vilarinho S, Choi M, Jain D, Malhotra A, Kulkarni S, Pashankar D, Phatak U, Patel M, Bale A, Mane S, Lifton RP, Mistry PK. Individual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology. Journal Of Hepatology 2014, 61: 1056-1063. PMID: 25016221, PMCID: PMC4203706, DOI: 10.1016/j.jhep.2014.06.038.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCarboxylic Ester HydrolasesChildCholestasisDNA Mutational AnalysisEnd Stage Liver DiseaseExomeFatal OutcomeFemaleGenes, RecessiveHepatolenticular DegenerationHeterozygoteHomozygoteHumansInfant, NewbornLiver FailureLiver Failure, AcuteMaleMembrane ProteinsMitochondrial ProteinsMolecular Sequence DataPedigreeReceptor, Notch2RNA Splice SitesSequence Homology, Amino AcidConceptsFatal acute liver failureWhole-exome sequencingAdvanced liver diseaseAcute liver failureIndeterminate etiologyYear old femaleLiver failureLiver diseaseMetabolic liver diseasePatient 3Treatment optionsPhenotypic spectrumPediatric liver failureDecompensated liver cirrhosisManagement of childrenOptimal treatment optionsAge 3 monthsNovel inborn errorLiver transplantAtypical presentationLiver cirrhosisHepatocerebral mitochondrial DNA depletion syndromePatient 1Patient 2Unknown etiology
2001
Bloom Syndrome in Sibs: First Reports of Hepatocellular Carcinoma and Wilms Tumor with Documented Anaplasia and Nephrogenic Rests
Jain D, Hui P, McNamara J, Schwartz D, German J, Reyes-Múgica M. Bloom Syndrome in Sibs: First Reports of Hepatocellular Carcinoma and Wilms Tumor with Documented Anaplasia and Nephrogenic Rests. Pediatric And Developmental Pathology 2001, 4: 585-589. PMID: 11826367, DOI: 10.1007/s10024001-0082-6.Peer-Reviewed Original Research
2000
Epstein-Barr virus RNA detection and glandular differentiation in nasopharyngeal carcinoma: report of 2 cases.
Jain D, Parkash V, Li M, Gill J, Crouch J, Howe G, Tallini G. Epstein-Barr virus RNA detection and glandular differentiation in nasopharyngeal carcinoma: report of 2 cases. Archives Of Pathology & Laboratory Medicine 2000, 124: 1369-72. PMID: 10975941, DOI: 10.5858/2000-124-1369-ebvrda.Peer-Reviewed Original ResearchConceptsGlandular differentiationNasopharyngeal typeUndifferentiated carcinomaEpstein-Barr virus latent membrane proteinEpstein-Barr virus genomeSquamous cell carcinomaLatent membrane proteinVirus RNA detectionCell carcinomaMost tumorsNasopharyngeal carcinomaCarcinomaTumorsRNA detectionUndifferentiated areasNasopharynxSitu hybridizationVirus genomeLight microscopyDifferentiationImmunohistochemistryPositivity