1997
Mutations in SPK1/RAD53 that specifically abolish checkpoint but not growth-related functions
Fay DS, Sun Z, Stern D. Mutations in SPK1/RAD53 that specifically abolish checkpoint but not growth-related functions. Current Genetics 1997, 31: 97-105. PMID: 9021124, DOI: 10.1007/s002940050181.Peer-Reviewed Original ResearchMeSH KeywordsAllelesCell Cycle ProteinsCheckpoint Kinase 2Cloning, MolecularElectrophoresis, Polyacrylamide GelGene Expression Regulation, EnzymologicGene Expression Regulation, FungalMutagenesisPlasmidsProtein KinasesProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence DeletionTransformation, GeneticConceptsCheckpoint functionKinase domainKinase activityEssential protein kinaseWild-type levelsGrowth-related functionsCheckpoint arrestProtein kinaseDeletional analysisN-terminusSPK1Cell cycleMutant allelesGrowth activityMutationsRad53Normal rateSaccharomycesMultiple stagesKinaseDomainCheckpointActivityAllelesRegulation
1992
An extra cysteine proximal to the transmembrane domain induces differential cross-linking of p185neu and p185neu.
Cao H, Bangalore L, Dompé C, Bormann BJ, Stern DF. An extra cysteine proximal to the transmembrane domain induces differential cross-linking of p185neu and p185neu. Journal Of Biological Chemistry 1992, 267: 20489-20492. PMID: 1356980, DOI: 10.1016/s0021-9258(19)88728-8.Peer-Reviewed Original ResearchA subdomain in the transmembrane domain is necessary for p185neu* activation.
Cao H, Bangalore L, Bormann BJ, Stern DF. A subdomain in the transmembrane domain is necessary for p185neu* activation. The EMBO Journal 1992, 11: 923-932. PMID: 1347745, PMCID: PMC556533, DOI: 10.1002/j.1460-2075.1992.tb05131.x.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAmino Acid SequenceAnimalsBase SequenceBlotting, WesternCell MembraneElectrophoresis, Polyacrylamide GelErbB ReceptorsGliomaGlutamatesGlutamic AcidMiceMolecular Sequence DataMutagenesis, Site-DirectedNeuroblastomaPrecipitin TestsProtein-Tyrosine KinasesProto-Oncogene ProteinsRatsReceptor, ErbB-2Signal TransductionValineConceptsTransmembrane domainTyrosine kinase activityKinase activityElevated tyrosine kinase activitySite-directed mutagenesisSpecific amino acidsEpidermal growth factor receptorGlutamic acidGrowth factor receptorEGF receptorPrimary structureAmino acidsFactor receptorProteinSpecific interactionsActivationDomainMutagenesisReceptorsMolecular weightAcidNeu proteinP185neuHigh propensityRole
1982
Coronavirus proteins: biogenesis of avian infectious bronchitis virus virion proteins
Stern DF, Sefton BM. Coronavirus proteins: biogenesis of avian infectious bronchitis virus virion proteins. Journal Of Virology 1982, 44: 794-803. PMID: 6294329, PMCID: PMC256336, DOI: 10.1128/jvi.44.3.794-803.1982.Peer-Reviewed Original ResearchCoronavirus proteins: structure and function of the oligosaccharides of the avian infectious bronchitis virus glycoproteins
Stern DF, Sefton BM. Coronavirus proteins: structure and function of the oligosaccharides of the avian infectious bronchitis virus glycoproteins. Journal Of Virology 1982, 44: 804-812. PMID: 6294330, PMCID: PMC256337, DOI: 10.1128/jvi.44.3.804-812.1982.Peer-Reviewed Original ResearchConceptsAvian coronavirus infectious bronchitis virusCoronavirus infectious bronchitis virusViral glycoproteinsMurine coronavirusFamily of virusesMembrane proteinsGp31E1 proteinVirus-infected cellsEndoglycosidase HUnusual modificationVirus virionsMembrane glycoproteinsGp28ProteinProduction of virionsEssential roleVirus polypeptidesOligosaccharide moietyViral maturationLife cycleVirus glycoproteinP23VirionsGlycoproteinStructural analysis of virion proteins of the avian coronavirus infectious bronchitis virus
Stern DF, Burgess L, Sefton BM. Structural analysis of virion proteins of the avian coronavirus infectious bronchitis virus. Journal Of Virology 1982, 42: 208-219. PMID: 6283141, PMCID: PMC256062, DOI: 10.1128/jvi.42.1.208-219.1982.Peer-Reviewed Original ResearchMeSH KeywordsCoronaviridaeElectrophoresis, Polyacrylamide GelGlycoproteinsInfectious bronchitis virusPeptidesTrypsinViral ProteinsVirionConceptsAmino-terminal domainAvian coronavirus infectious bronchitis virusCoronavirus infectious bronchitis virusPartial proteolytic digestionVirion proteinsTwo-dimensional tryptic peptide mappingProteolytic digestionNon-glycosylated proteinsNon-glycosylated proteinTryptic peptide mappingVitro translationRelated proteinsGp31Major polypeptidesFormyl-methionineInfectious bronchitis virusProteinP23Peptide mappingInfected cellsProteolytic fragmentsMinor speciesMarked polymorphismGp28Bronchitis virus