Sex differences in medial prefrontal and parietal cortex structure in children with disruptive behavior
Ibrahim K, Kalvin C, Li F, He G, Pelphrey KA, McCarthy G, Sukhodolsky DG. Sex differences in medial prefrontal and parietal cortex structure in children with disruptive behavior. Developmental Cognitive Neuroscience 2020, 47: 100884. PMID: 33254067, PMCID: PMC7704291, DOI: 10.1016/j.dcn.2020.100884.Peer-Reviewed Original ResearchConceptsDisruptive behavior disordersGray matter volumeCortical thicknessMatter volumeSex differencesDisruptive behavior severityCross-sectional studySex-specific associationsDisruptive behaviorLeft ventromedial prefrontal cortexWhole-brain analysisSurface-based morphometryStructural MRI dataHealthy controlsSex-specific differencesNeural biomarkersTarget-based treatmentVentromedial prefrontal cortexMedial prefrontalBehavior disorderPrefrontal cortexBrain structuresSupramarginal gyrusRespective controlsVmPFC volumeFixel-Based Diffusion Magnetic Resonance Imaging Reveals Novel Associations Between White Matter Microstructure and Childhood Aggressive Behavior
Grazioplene R, Tseng WL, Cimino K, Kalvin C, Ibrahim K, Pelphrey KA, Sukhodolsky DG. Fixel-Based Diffusion Magnetic Resonance Imaging Reveals Novel Associations Between White Matter Microstructure and Childhood Aggressive Behavior. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2020, 5: 490-498. PMID: 32144044, PMCID: PMC7214205, DOI: 10.1016/j.bpsc.2019.12.018.Peer-Reviewed Original ResearchConceptsWhite matter densityCorpus callosumFiber densityAggressive behaviorCingulum bundleAbnormal interhemispheric connectivityHealthy control childrenWhite matter abnormalitiesAttention-deficit/hyperactivity disorderMiddle cerebellar peduncleSuperior thalamic radiationMagnetic resonance imagingInferior fronto-occipital fasciculusWhole-brain analysisInferior longitudinal fasciculusFronto-occipital fasciculusPotential neural mechanismsWhite matter microstructureDiffusion magnetic resonance imagingInterhemispheric connectivityCortical pathwaysCerebellar peduncleChild Behavior ChecklistThalamic radiationFiber bundle density