2021
Increased amygdala and decreased frontolimbic r esting- s tate functional connectivity in children with aggressive behavior
Sukhodolsky DG, Ibrahim K, Kalvin CB, Jordan RP, Eilbott J, Hampson M. Increased amygdala and decreased frontolimbic r esting- s tate functional connectivity in children with aggressive behavior. Social Cognitive And Affective Neuroscience 2021, 17: 634-644. PMID: 34850939, PMCID: PMC9250305, DOI: 10.1093/scan/nsab128.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulateFunctional connectivityAnterior cingulateDorsolateral prefrontal cortical regionsResting-state brain connectivityAggressive behaviorResting-state functional connectivityIntrinsic connectivity distributionAmygdala-prefrontal circuitryAnterior cingulate cortexIntrinsic functional connectivityPrefrontal cortical regionsHealthy controlsAmygdala connectivityGreater severityVentromedial prefrontal cortexCingulate cortexFunctional MRI dataCortical regionsMedial prefrontalMaladaptive aggressionPrefrontal cortexBrain connectivitySeverity of aggressionTreatment-seeking children
2017
Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder
Yang YJ, Sukhodolsky DG, Lei J, Dayan E, Pelphrey KA, Ventola P. Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder. Journal Of Neurodevelopmental Disorders 2017, 9: 1. PMID: 28115995, PMCID: PMC5240249, DOI: 10.1186/s11689-017-9183-z.Peer-Reviewed Original ResearchAutism spectrum disorderAutism symptom severityMedial prefrontal cortexAnterior cingulate cortexLow disruptive behaviorCore ASD symptomsBiological motionNeural basisDMN deactivationDisruptive behaviorADHD symptomsASD symptomsSpectrum disorderAnxiety symptomsSymptom severityPosterior superior temporal sulcusBetween-group analysisDefault mode network deactivationDistinct neural basesSuperior temporal sulcusInferior frontal gyrusHigh disruptive behaviorLateral parietal cortexASD participantsNeural underpinnings