2012
Cortical Dendritic Spine Heads Are Not Electrically Isolated by the Spine Neck from Membrane Potential Signals in Parent Dendrites
Popovic MA, Gao X, Carnevale NT, Zecevic D. Cortical Dendritic Spine Heads Are Not Electrically Isolated by the Spine Neck from Membrane Potential Signals in Parent Dendrites. Cerebral Cortex 2012, 24: 385-395. PMID: 23054810, PMCID: PMC3888368, DOI: 10.1093/cercor/bhs320.Peer-Reviewed Original Research
2011
Somatic Membrane Potential and Kv1 Channels Control Spike Repolarization in Cortical Axon Collaterals and Presynaptic Boutons
Foust AJ, Yu Y, Popovic M, Zecevic D, McCormick DA. Somatic Membrane Potential and Kv1 Channels Control Spike Repolarization in Cortical Axon Collaterals and Presynaptic Boutons. Journal Of Neuroscience 2011, 31: 15490-15498. PMID: 22031895, PMCID: PMC3225031, DOI: 10.1523/jneurosci.2752-11.2011.Peer-Reviewed Original ResearchMeSH Keywords4-AminopyridineAnimalsAxonsBiophysical PhenomenaComputer SimulationCrystallinsDose-Response Relationship, DrugElapid VenomsElectric StimulationFemaleGreen Fluorescent ProteinsIn Vitro TechniquesMaleMembrane PotentialsMiceMice, TransgenicModels, NeurologicalMu-CrystallinsNerve NetNeuronsPatch-Clamp TechniquesPotassium Channel BlockersPresynaptic TerminalsShaker Superfamily of Potassium ChannelsSomatosensory CortexStyrenesTetraethylammoniumConceptsAxon collateralsPresynaptic boutonsKv1 channelsSpike repolarizationPresynaptic terminalsSubthreshold depolarizationAction potentialsΑ-dendrotoxinLayer 5 pyramidal cellsIntracortical axon collateralsSynaptic neurotransmitter releaseMouse brain slicesSomatic membrane potentialKv1 subunitsPyramidal cellsSynaptic transmissionBrain slicesVoltage-sensitive dyeLow dosesNeurotransmitter releaseSynaptic strengthBoutonsCollateralsRepolarizationIon channels
2010
Action Potentials Initiate in the Axon Initial Segment and Propagate through Axon Collaterals Reliably in Cerebellar Purkinje Neurons
Foust A, Popovic M, Zecevic D, McCormick DA. Action Potentials Initiate in the Axon Initial Segment and Propagate through Axon Collaterals Reliably in Cerebellar Purkinje Neurons. Journal Of Neuroscience 2010, 30: 6891-6902. PMID: 20484631, PMCID: PMC2990270, DOI: 10.1523/jneurosci.0552-10.2010.Peer-Reviewed Original ResearchConceptsAxon initial segmentAxon collateralsAction potentialsPurkinje neuronsComplex spikesLocal axon collateralsCerebellar Purkinje neuronsInitial segmentFast action potentialsAxon branch pointsSynaptic inputsVoltage-sensitive dyeCerebellar cortexNeuronal processingSpike initiationDischarge frequencySingle trialCollateralsOutput cellsNeurons
2008
Functional Structure of the Mitral Cell Dendritic Tuft in the Rat Olfactory Bulb
Djurisic M, Popovic M, Carnevale N, Zecevic D. Functional Structure of the Mitral Cell Dendritic Tuft in the Rat Olfactory Bulb. Journal Of Neuroscience 2008, 28: 4057-4068. PMID: 18400905, PMCID: PMC6670455, DOI: 10.1523/jneurosci.5296-07.2008.Peer-Reviewed Original ResearchConceptsMitral cellsDendritic tuftsOlfactory bulbGlomerular tuftPrincipal projection neuronsVoltage-sensitive dye recordingRat olfactory bulbSubthreshold synaptic potentialsPrimary dendritesProjection neuronsSynaptic potentialsSame neuronsEPSPsElectrical compartmentsDendritic branchesAnatomical studySynchronized activationDendritic surfaceNeuronsSynapsesCell typesAverage rangePassive electrical propertiesCellsTufts
2007
Dendritic signals from rat hippocampal CA1 pyramidal neurons during coincident pre‐ and post‐synaptic activity: a combined voltage‐ and calcium‐imaging study
Canepari M, Djurisic M, Zecevic D. Dendritic signals from rat hippocampal CA1 pyramidal neurons during coincident pre‐ and post‐synaptic activity: a combined voltage‐ and calcium‐imaging study. The Journal Of Physiology 2007, 580: 463-484. PMID: 17272348, PMCID: PMC2075540, DOI: 10.1113/jphysiol.2006.125005.Peer-Reviewed Original ResearchConceptsLong-term potentiationHippocampal CA1 pyramidal neuronsCA1 pyramidal neuronsPost-synaptic activityPyramidal neuronsRat hippocampal CA1 pyramidal neuronsActivity-dependent long-term synaptic plasticityDendritic action potentialsCalcium imaging studiesLong-term synaptic plasticityDifferent dendritic locationsDendritic signalsDendritic locationMembrane potential transientsNMDA receptorsDendritic arborsPeak amplitudeStimulation protocolSynaptic plasticityAction potentialsMembrane depolarizationDendritic regionsBaselineNeuronsInduction
1999
Fast Optical Recordings of Membrane Potential Changes From Dendrites of Pyramidal Neurons
Antic S, Major G, Zecevic D. Fast Optical Recordings of Membrane Potential Changes From Dendrites of Pyramidal Neurons. Journal Of Neurophysiology 1999, 82: 1615-1621. PMID: 10482775, DOI: 10.1152/jn.1999.82.3.1615.Peer-Reviewed Original ResearchConceptsBasolateral dendritesApical dendritesBrain slicesVoltage-sensitive dyeNeuronal processesPyramidal neuronsMembrane potential transientsPharmacological effectsSynaptic stimulationAction potentialsInvertebrate neuronsNeuronsPatch electrodeSingle neuronsElectrical activityMembrane potential changesFast optical recordingDistal processesVertebrate neuronsOptical recordingDendritesH incubation periodStimulationApical processesRecordings
1995
Optical recording from cerebellar Purkinje cells using intracellularly injected voltage-sensitive dyes
Kogan A, Ross W, Zecevic D, Lasser-Ross N. Optical recording from cerebellar Purkinje cells using intracellularly injected voltage-sensitive dyes. Brain Research 1995, 700: 235-239. PMID: 8624715, DOI: 10.1016/0006-8993(95)00956-q.Peer-Reviewed Original Research
1993
Optical measurement of action potential activity in invertebrate ganglia.
Wu J, Falk C, Cohen L, Tsau Y, Zecevic D. Optical measurement of action potential activity in invertebrate ganglia. The Journal Of Physiological Sciences 1993, 43 Suppl 1: s21-9. PMID: 8271496.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1987
Optical recording of action potential propagation in demyelinated frog nerve
Shrager P, Chiu SY, Ritchie JM, Zecevic D, Cohen LB. Optical recording of action potential propagation in demyelinated frog nerve. Biophysical Journal 1987, 51: 351-355. PMID: 3493812, PMCID: PMC1329897, DOI: 10.1016/s0006-3495(87)83342-8.Peer-Reviewed Original Research