2020
Supplemental screening in the dense breast: does molecular breast imaging have a role?
Rhodes DJ. Supplemental screening in the dense breast: does molecular breast imaging have a role? Menopause The Journal Of The North American Menopause Society 2020, 27: 110-112. PMID: 31880677, DOI: 10.1097/gme.0000000000001471.Peer-Reviewed Original Research
2019
Molecular Breast Imaging in Patients with Suspicious Calcifications
Hunt K, Hruska C, Johnson M, Conners A, O’connor M, Rhodes D, Basappa S, Wahner-Roedler D. Molecular Breast Imaging in Patients with Suspicious Calcifications. Journal Of Breast Imaging 2019, 1: 303-309. PMID: 38424809, DOI: 10.1093/jbi/wbz054.Peer-Reviewed Original ResearchMolecular breast imagingSuspicious calcificationsNegative predictive valueTelluride gamma cameraPredictive valueMedian pathologic sizeInvasive ductal cancerOccult breast cancerInjection of TcAreas of calcificationBreast imagingNuclear medicine techniquesPrebiopsy settingGamma cameraBiopsy findingsDuctal cancerPathologic sizeIncidental lesionsDuctal carcinomaInvasive cancerAdditional biopsiesBreast cancerStereotactic biopsyBiopsyMolecular breastClassification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network
Carter RE, Attia ZI, Geske JR, Conners AL, Whaley DH, Hunt KN, O’Connor M, Rhodes DJ, Hruska CB. Classification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network. JCO Clinical Cancer Informatics 2019, 3: 1-11. PMID: 30807208, PMCID: PMC6446086, DOI: 10.1200/cci.18.00133.Peer-Reviewed Original ResearchConceptsConvolutional neural networkNeural networkDeep learning modelsImage convolutionLearning modelModel performanceBackground parenchymal uptakeTesting dataComputer algorithmAlgorithmExpert radiologistsNetworkDirect matchingDirect matchAccuracyImagesClassificationResearch purposesPerformanceBreast imagingConvolutionEncodingMatchingModelingTrainingMolecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report
Samreen N, Hunt KN, Hruska CB, Rhodes DJ. Molecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report. Clinical Case Reports 2019, 7: 442-444. PMID: 30899468, PMCID: PMC6406216, DOI: 10.1002/ccr3.1945.Peer-Reviewed Original Research
2017
Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging
Swanson TN, Tran TD, Hruska CB, Solberg CM, Rhodes DJ, Hunt KN, Conners AL, O'Connor MK. Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging. Journal Of Medical Imaging And Radiation Sciences 2017, 49: 39-43. PMID: 30479286, DOI: 10.1016/j.jmir.2017.08.003.Peer-Reviewed Original ResearchConceptsMolecular breast imagingExact testFisher's exact testDuration of examinationBreast imagingPatients' opinionsPatient acceptanceDose reductionExamination comfortMost womenPatient comfortFemale volunteersRadiation doseExamination typesDoseExamination preferencesImagingPatientsGroupNumber of strategiesSurvey responsesVolunteersWomen
2016
Molecular Breast Imaging and the 2016 Update to the ACR Appropriateness Criteria for Breast Cancer Screening
Covington MF, Rhodes DJ, Pizzitola VJ. Molecular Breast Imaging and the 2016 Update to the ACR Appropriateness Criteria for Breast Cancer Screening. Journal Of The American College Of Radiology 2016, 13: 1408. PMID: 27916107, DOI: 10.1016/j.jacr.2016.09.017.Peer-Reviewed Original Research
2015
Direct-Conversion Molecular Breast Imaging of Invasive Breast Cancer: Imaging Features, Extent of Invasive Disease, and Comparison Between Invasive Ductal and Lobular Histology.
Conners AL, Jones KN, Hruska CB, Geske JR, Boughey JC, Rhodes DJ. Direct-Conversion Molecular Breast Imaging of Invasive Breast Cancer: Imaging Features, Extent of Invasive Disease, and Comparison Between Invasive Ductal and Lobular Histology. American Journal Of Roentgenology 2015, 205: w374-81. PMID: 26295674, PMCID: PMC8900216, DOI: 10.2214/ajr.14.13502.Peer-Reviewed Original ResearchConceptsInvasive breast cancerMolecular breast imagingInvasive tumor fociBreast imaging examinationsTumor fociMolecular breastBreast cancerImaging featuresInvasive diseasePathology reportsImaging examinationsHistologic profileBreast imagingBreast imaging findingsChi-square testLobular histologyHistologic subtypeInvasive DuctalImaging findingsInvasive cancerBenign reasonsInvasive fociTumor appearanceBlinded reviewLesion typeEffect of Menstrual Cycle Phase on Background Parenchymal Uptake at Molecular Breast Imaging
Hruska CB, Conners AL, Vachon CM, O'Connor MK, Shuster LT, Bartley AC, Rhodes DJ. Effect of Menstrual Cycle Phase on Background Parenchymal Uptake at Molecular Breast Imaging. Academic Radiology 2015, 22: 1147-1156. PMID: 26112057, PMCID: PMC4532620, DOI: 10.1016/j.acra.2015.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreastBreast DensityChromatography, LiquidCohort StudiesEstradiolEstroneFemaleFollicle Stimulating HormoneFollicular PhaseHumansLuteal PhaseMammographyMiddle AgedMolecular ImagingPremenopauseProgesteroneProspective StudiesRadiopharmaceuticalsSex Hormone-Binding GlobulinTandem Mass SpectrometryTechnetium Tc 99m SestamibiTestosteroneConceptsBackground parenchymal uptakeMolecular breast imagingMenstrual cycle phaseLuteal phaseMenstrual cycleNondense breastsFollicular phaseHormone levelsParenchymal uptakeDense breastsExogenous hormone useRegular menstrual cyclesLevels of TCCycle phaseNormal fibroglandular tissuePremenopausal volunteersPremenopausal womenHormone useSpearman correlation coefficientBreast imagingStudy radiologistsMammographic densityBreastFibroglandular tissueWomenFactors Influencing the Uptake of 99mTc-Sestamibi in Breast Tissue on Molecular Breast Imaging
O’Connor M, Hruska CB, Tran TD, Swanson T, Conners AL, Jones K, Rhodes DJ. Factors Influencing the Uptake of 99mTc-Sestamibi in Breast Tissue on Molecular Breast Imaging. Journal Of Nuclear Medicine Technology 2015, 43: 13-20. PMID: 25613340, DOI: 10.2967/jnmt.114.150128.Peer-Reviewed Original ResearchConceptsMolecular breast imagingBreast tissuePrandial statusOptimal patient preparationPeripheral blood flowBody surface areaCounts/Type of interventionBreast imagingPatient heightPeripheral warmingStudy groupBlood flowSestamibiBreast activityPatient preparationFed stateCount densityMetabolic statusReference groupOblique viewMediolateral oblique viewTissueInterventionBreast thickness
2012
Gamma camera breast imaging lexicon.
Conners AL, Maxwell RW, Tortorelli CL, Hruska CB, Rhodes DJ, Boughey JC, Berg WA. Gamma camera breast imaging lexicon. American Journal Of Roentgenology 2012, 199: w767-74. PMID: 23169751, DOI: 10.2214/ajr.11.8298.Peer-Reviewed Original ResearchEvaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi
Hruska CB, Rhodes DJ, Collins DA, Tortorelli CL, Askew JW, O'Connor MK. Evaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi. Journal Of Women's Health 2012, 21: 730-738. PMID: 22404787, DOI: 10.1089/jwh.2011.3267.Peer-Reviewed Original ResearchConceptsMolecular breast imagingBreast diseaseBreast cancerDiagnostic yieldMyocardial perfusionHigh-risk benign breast lesionsMyocardial perfusion stress testingRecent negative mammogramStress myocardial perfusionHigh diagnostic yieldStress myocardial perfusion studyBenign breast lesionsNumber of cancersMyocardial perfusion studiesBreast imagingNew cancersRecent mammogramSestamibi injectionNegative mammogramUnnecessary workupPerfusion studiesBreast lesionsCancerIsotope injectionWomen
2010
Development of radiation dose reduction techniques for cadmium zinc telluride detectors in molecular breast imaging
O'Connor M, Hruska C, Weinmann A, Manduca A, Rhodes D. Development of radiation dose reduction techniques for cadmium zinc telluride detectors in molecular breast imaging. Proceedings Of SPIE--the International Society For Optical Engineering 2010, 7806: 780603-780603-15. DOI: 10.1117/12.864649.Peer-Reviewed Original Research
2008
Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors.
Hruska CB, Phillips SW, Whaley DH, Rhodes DJ, O'Connor MK. Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors. American Journal Of Roentgenology 2008, 191: 1805-15. PMID: 19020253, PMCID: PMC3885170, DOI: 10.2214/ajr.07.3693.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsEquipment DesignEquipment Failure AnalysisFemaleGamma CamerasHumansImage EnhancementMiddle AgedMolecular Probe TechniquesRadionuclide ImagingRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificitySingle-Blind MethodTechnetium Tc 99m SestamibiConceptsMolecular breast imagingMolecular breastBI-RADS category 4Breast imagingMBq of technetiumSmall breast tumorsTelluride gamma cameraGamma cameraSubcentimeter lesionsUptake scoreAdditional cancersBlinded reviewDetection of cancerBreast tumorsLesionsSmall lesionsBreastPatientsBreast lesionsBlinded readersCancerOblique viewCategory 4Mediolateral oblique viewTumorsScientific Impact Recognition Award: Molecular breast imaging: A review of the Mayo Clinic experience
Hruska CB, Boughey JC, Phillips SW, Rhodes DJ, Wahner-Roedler DL, Whaley DH, Degnim AC, O'Connor MK. Scientific Impact Recognition Award: Molecular breast imaging: A review of the Mayo Clinic experience. The American Journal Of Surgery 2008, 196: 470-476. PMID: 18723155, PMCID: PMC2603338, DOI: 10.1016/j.amjsurg.2008.06.005.Peer-Reviewed Original ResearchConceptsMolecular breast imagingInvasive ductal carcinomaInvasive lobular carcinomaDuctal carcinomaLobular carcinomaHigh-risk patientsExtent of diseaseMayo Clinic experienceBreast cancer screeningSurgical treatment planningBreast imagingMultifocal diseaseCancer screeningInstitutional protocolAdditional diseaseClinic experienceCarcinomaDiseaseFunctional uptakeTreatment planningMBI studiesPromising roleTumorsBreastCancer detection
2007
Molecular breast imaging: advances and limitations of a scintimammographic technique in patients with small breast tumors
O'Connor M, Phillips S, Hruska C, Rhodes D, Collins D. Molecular breast imaging: advances and limitations of a scintimammographic technique in patients with small breast tumors. Clinical Imaging 2007, 31: 295. DOI: 10.1016/j.clinimag.2007.04.010.Peer-Reviewed Original ResearchMolecular breast imagingSmall breast tumorsBreast tumorsEvidence of cancerFalse-positive scansLarger patient populationMalignant breast tumorsStandard mammographic viewsMBq technetiumOccult tumorsPatient populationMalignant tumorsPatientsTumorsBreast tissueSubjective discomfortBiopsySurgeryMammographic viewsGamma cameraBreast imagingBreast thicknessPreliminary studyRegular detectionView gamma cameraMolecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors
O'Connor MK, Phillips SW, Hruska CB, Rhodes DJ, Collins DA. Molecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors. The Breast Journal 2007, 13: 3-11. PMID: 17214787, DOI: 10.1111/j.1524-4741.2006.00356.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularCarcinoma, PapillaryFemaleHumansMammographyMiddle AgedPredictive Value of TestsRadionuclide ImagingSensitivity and SpecificityTechnetium Tc 99m SestamibiUltrasonographyConceptsMolecular breast imagingSmall breast tumorsBreast tumorsEvidence of cancerFalse-positive scansLarger patient populationMalignant breast tumorsStandard mammographic viewsMBq TcOccult tumorsPatient populationMalignant tumorsPositive scansPatientsTumorsBreast tissueSubjective discomfortBiopsySurgeryMammographic viewsGamma cameraBreast imagingBreast thicknessPreliminary studyRegular detection