2020
Supplemental screening in the dense breast: does molecular breast imaging have a role?
Rhodes DJ. Supplemental screening in the dense breast: does molecular breast imaging have a role? Menopause The Journal Of The North American Menopause Society 2020, 27: 110-112. PMID: 31880677, DOI: 10.1097/gme.0000000000001471.Peer-Reviewed Original Research
2019
Molecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report
Samreen N, Hunt KN, Hruska CB, Rhodes DJ. Molecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report. Clinical Case Reports 2019, 7: 442-444. PMID: 30899468, PMCID: PMC6406216, DOI: 10.1002/ccr3.1945.Peer-Reviewed Original Research
2016
Dense Breasts: What Do Our Patients Need to Be Told and Why?
Throckmorton AD, Rhodes DJ, Hughes KS, Degnim AC, Dickson-Witmer D. Dense Breasts: What Do Our Patients Need to Be Told and Why? Annals Of Surgical Oncology 2016, 23: 3119-3127. PMID: 27401446, DOI: 10.1245/s10434-016-5400-3.Peer-Reviewed Original ResearchConceptsBreast cancer prevention strategiesEvidence-based consensus guidelinesDense breastsBreast cancer risk assessmentOnly risk factorCancer prevention strategiesCancer risk assessmentDelaying diagnosisCertain patientsConsensus guidelinesRisk factorsDensity notificationSupplemental imagingPrevention strategiesPatientsBreast densityBreastRisk assessmentCancerDiagnosisWomen
2015
Effect of Menstrual Cycle Phase on Background Parenchymal Uptake at Molecular Breast Imaging
Hruska CB, Conners AL, Vachon CM, O'Connor MK, Shuster LT, Bartley AC, Rhodes DJ. Effect of Menstrual Cycle Phase on Background Parenchymal Uptake at Molecular Breast Imaging. Academic Radiology 2015, 22: 1147-1156. PMID: 26112057, PMCID: PMC4532620, DOI: 10.1016/j.acra.2015.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreastBreast DensityChromatography, LiquidCohort StudiesEstradiolEstroneFemaleFollicle Stimulating HormoneFollicular PhaseHumansLuteal PhaseMammographyMiddle AgedMolecular ImagingPremenopauseProgesteroneProspective StudiesRadiopharmaceuticalsSex Hormone-Binding GlobulinTandem Mass SpectrometryTechnetium Tc 99m SestamibiTestosteroneConceptsBackground parenchymal uptakeMolecular breast imagingMenstrual cycle phaseLuteal phaseMenstrual cycleNondense breastsFollicular phaseHormone levelsParenchymal uptakeDense breastsExogenous hormone useRegular menstrual cyclesLevels of TCCycle phaseNormal fibroglandular tissuePremenopausal volunteersPremenopausal womenHormone useSpearman correlation coefficientBreast imagingStudy radiologistsMammographic densityBreastFibroglandular tissueWomenDiagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts.
Hruska CB, Conners AL, Jones KN, O'Connor MK, Moriarty JP, Boughey JC, Rhodes DJ. Diagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts. American Journal Of Roentgenology 2015, 204: 1345-53. PMID: 26001247, PMCID: PMC5036572, DOI: 10.2214/ajr.14.13306.Peer-Reviewed Original ResearchConceptsBenign biopsy rateDiagnostic workupBiopsy rateDense breastsAdditional diagnostic workupCancer detection rateMammography of womenBreast imaging examinationsPositive predictive valueDual-head gamma cameraImaging examinationsPredictive valueMolecular breastBiopsyPatientsWorkupBreastScreening mammographyCancerWomenMammographyMalignancyReference standardGamma cameraDetection rateBackground parenchymal uptake during molecular breast imaging and associated clinical factors.
Hruska CB, Rhodes DJ, Conners AL, Jones KN, Carter RE, Lingineni RK, Vachon CM. Background parenchymal uptake during molecular breast imaging and associated clinical factors. American Journal Of Roentgenology 2015, 204: w363-70. PMID: 25714323, PMCID: PMC4423612, DOI: 10.2214/ajr.14.12979.Peer-Reviewed Original ResearchConceptsBackground parenchymal uptakePostmenopausal hormone therapyParenchymal uptakeBreast cancerMolecular breast imagingHormone therapyClinical factorsMammographic densityDense breastsBI-RADS density categoriesChi-square testMenopausal statusPatient characteristicsHormonal contraceptivesEligible participantsGail modelMenstrual cycleSubsequent riskPrevious mammogramsMolecular breastBreast implantsUnderlying causeCancerBreastWomenJournal club: molecular breast imaging at reduced radiation dose for supplemental screening in mammographically dense breasts.
Rhodes DJ, Hruska CB, Conners AL, Tortorelli CL, Maxwell RW, Jones KN, Toledano AY, O'Connor MK. Journal club: molecular breast imaging at reduced radiation dose for supplemental screening in mammographically dense breasts. American Journal Of Roentgenology 2015, 204: 241-51. PMID: 25615744, PMCID: PMC4423604, DOI: 10.2214/ajr.14.13357.Peer-Reviewed Original ResearchConceptsCancer detection rateMolecular breast imagingDense breastsOverall cancer detection rateInvasive cancer detection rateDetection ratePositive predictive valueRadiation dose reductionAsymptomatic womenBilateral cancerDCIS detectionSupplemental screeningInvasive diseaseBiopsy rateDose reductionReduced radiation dosePredictive valueMolecular breastBreastScreening mammographyDiagnostic performanceRadiopharmaceutical activityCancerRadiation doseMammography
2014
Breast density legislation. Implications for patients and primary care providers.
Rhodes DJ, Conners AL. Breast density legislation. Implications for patients and primary care providers. Minnesota Medicine 2014, 97: 43-8. PMID: 25158436.Peer-Reviewed Original Research
2008
Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors.
Hruska CB, Phillips SW, Whaley DH, Rhodes DJ, O'Connor MK. Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors. American Journal Of Roentgenology 2008, 191: 1805-15. PMID: 19020253, PMCID: PMC3885170, DOI: 10.2214/ajr.07.3693.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsEquipment DesignEquipment Failure AnalysisFemaleGamma CamerasHumansImage EnhancementMiddle AgedMolecular Probe TechniquesRadionuclide ImagingRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificitySingle-Blind MethodTechnetium Tc 99m SestamibiConceptsMolecular breast imagingMolecular breastBI-RADS category 4Breast imagingMBq of technetiumSmall breast tumorsTelluride gamma cameraGamma cameraSubcentimeter lesionsUptake scoreAdditional cancersBlinded reviewDetection of cancerBreast tumorsLesionsSmall lesionsBreastPatientsBreast lesionsBlinded readersCancerOblique viewCategory 4Mediolateral oblique viewTumorsScientific Impact Recognition Award: Molecular breast imaging: A review of the Mayo Clinic experience
Hruska CB, Boughey JC, Phillips SW, Rhodes DJ, Wahner-Roedler DL, Whaley DH, Degnim AC, O'Connor MK. Scientific Impact Recognition Award: Molecular breast imaging: A review of the Mayo Clinic experience. The American Journal Of Surgery 2008, 196: 470-476. PMID: 18723155, PMCID: PMC2603338, DOI: 10.1016/j.amjsurg.2008.06.005.Peer-Reviewed Original ResearchConceptsMolecular breast imagingInvasive ductal carcinomaInvasive lobular carcinomaDuctal carcinomaLobular carcinomaHigh-risk patientsExtent of diseaseMayo Clinic experienceBreast cancer screeningSurgical treatment planningBreast imagingMultifocal diseaseCancer screeningInstitutional protocolAdditional diseaseClinic experienceCarcinomaDiseaseFunctional uptakeTreatment planningMBI studiesPromising roleTumorsBreastCancer detection