2020
Core Principles in Nutrition: Nutrient Needs, Metabolism, and Potential Influences on Infectious Diseases
Barffour M, Humphries D. Core Principles in Nutrition: Nutrient Needs, Metabolism, and Potential Influences on Infectious Diseases. Nutrition And Health 2020, 23-82. DOI: 10.1007/978-3-030-56913-6_2.Peer-Reviewed Original ResearchDisease outcomeInfectious diseasesImpact of undernutritionInfectious disease outcomesProtein-calorie deficitsWorld Health Organization monographElevated riskMicronutrient interventionsImmune systemNutritional statusSpecific macronutrientsInfectionMalnutritionDiseaseOutcomesMetabolismCurrent understandingPotential pathwaysUndernutritionMortalityPotential influencePublic Health and Clinical Implications of Nutrition-Infection Interactions
Vermund S, Scott M, Humphries D. Public Health and Clinical Implications of Nutrition-Infection Interactions. Nutrition And Health 2020, 459-481. DOI: 10.1007/978-3-030-56913-6_16.Peer-Reviewed Original ResearchInfectious agentsNutritional statusClinical implicationsRole of obesityDefinitive risk factorsSeverity of malariaSuboptimal nutritional statusMajor infectious agentsHealth of personsClinical courseClinical managementRisk factorsClinical nutritionHigh mortalityInfectious diseasesCOVID-19ObesityPublic healthInfectionDiseaseSeverityNutritionHealthBacterial diseasesStatusPathways Linking Nutritional Status and Infectious Disease: Causal and Conceptual Frameworks
Humphries D, Scott M, Vermund S. Pathways Linking Nutritional Status and Infectious Disease: Causal and Conceptual Frameworks. Nutrition And Health 2020, 3-22. DOI: 10.1007/978-3-030-56913-6_1.Peer-Reviewed Original ResearchHost nutritional statusNutritional statusInfectious diseasesExperience of infectionImpact of nutritionInfluence of nutritionImmunological responseDrug interventionEpidemiological studiesHost responseDisease severityInfectionMechanisms of causalityDiseaseMicrobial pathogenesisFuture studiesStatusUnderstanding of causationNutritionPathogensSame populationPathogenesisMalnutritionSeverityResponse
2012
Nutritional risk factors for hookworm infection among school age children in the Kintampo North Municipality, Ghana
Humphries D, Simms B, Davey D, Otchere J, Quagraine J, Berg E, Newton S, Harrison L, Boakye D, Wilson M, Cappello M. Nutritional risk factors for hookworm infection among school age children in the Kintampo North Municipality, Ghana. The FASEB Journal 2012, 26: 1028.6-1028.6. DOI: 10.1096/fasebj.26.1_supplement.1028.6.Peer-Reviewed Original ResearchHookworm infectionKintampo North MunicipalityRisk factorsInfection statusSchool-aged childrenNutritional risk factorsDietary risk factorsMalaria infection statusSignificant risk factorsDietary diversityDegree of stuntingLow-intensity infectionsChildren ages 6Recent dewormingClinical sequelaeResults PrevalenceHigh prevalenceFood groupsIntensity infectionsNutritional statusCross-sectional sampleHookwormInfectionAnemiaHAZ scores
2011
Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure
Humphries D, Mosites E, Otchere J, Twum WA, Woo L, Jones-Sanpei H, Harrison LM, Bungiro RD, Benham-Pyle B, Bimi L, Edoh D, Bosompem K, Wilson M, Cappello M. Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure. American Journal Of Tropical Medicine And Hygiene 2011, 84: 792-800. PMID: 21540391, PMCID: PMC3083749, DOI: 10.4269/ajtmh.2011.11-0003.Peer-Reviewed Original ResearchConceptsPoor nutritional statusHookworm infectionRisk factorsNutritional statusOverall egg reduction rateSerum immunoglobulin G (IgG) reactivitiesCross-sectional pilot studyEgg reduction rateImmunoglobulin G reactivityKintampo North MunicipalityAlbendazole therapyKintampo NorthMalaria coinfectionTreatment failureOverall prevalenceHigh prevalenceRepeat examinationEgg excretionSecretory antigensInfectionPilot studyCoinfectionSignificant reductionTherapyHigh rate