1999
Comparison between a Whole Blood Interferon-γ Release Assay and Tuberculin Skin Testing for the Detection of Tuberculosis Infection among Patients at Risk for Tuberculosis Exposure
Kimura M, Converse P, Astemborski J, Rothel J, Vlahov D, Comstock G, Graham N, Chaisson R, Bishai W. Comparison between a Whole Blood Interferon-γ Release Assay and Tuberculin Skin Testing for the Detection of Tuberculosis Infection among Patients at Risk for Tuberculosis Exposure. The Journal Of Infectious Diseases 1999, 179: 1297-1300. PMID: 10191241, DOI: 10.1086/314707.Peer-Reviewed Original ResearchConceptsTuberculin skin testIFN-gamma releaseTuberculosis infectionWhole-Blood Interferon-γ Release AssayStandard tuberculin skin testInterferon-γ release assaysPercent agreementCulture-confirmed tuberculosisHIV-seropositive subjectsTuberculin skin testingHuman immunodeficiency virusInterferon-gamma releaseIntravenous drug usersSingle blood drawSeronegative patientsTuberculosis exposureSkin testingUninfected personsImmunodeficiency virusSkin testBlood drawUrban BaltimoreDrug usersRelease assaysFurther evaluationCriteria for assessing cutaneous anergy in women with or at risk for HIV infection
Klein R, Flanigan T, Schuman P, Smith D, Vlahov D, Group* F. Criteria for assessing cutaneous anergy in women with or at risk for HIV infection. Journal Of Allergy And Clinical Immunology 1999, 103: 93-98. PMID: 9893191, DOI: 10.1016/s0091-6749(99)70531-2.Peer-Reviewed Original ResearchConceptsHIV statusCutaneous anergyHIV infectionTetanus antigensTuberculin reactionLevel of immunodeficiencyHIV-seronegative womenPositive tuberculin reactionAcademic medical centerAnergy testingLow CD4Seronegative subjectsHIV-seronegativeMumps antigenSeropositive subjectsSeropositive womenHIV-seropositiveLymphocyte levelsRisk womenTuberculin antigenTetanus toxoidCutaneous testingMedical CenterClinical utilityAntigen combinations
1998
Tuberculosis Risk in Funeral Home Employees
Gershon R, Vlahov D, Escamilla-Cejudo J, Badawi M, McDiarmid M, Karkashian C, Grimes M, Comstock G. Tuberculosis Risk in Funeral Home Employees. Journal Of Occupational And Environmental Medicine 1998, 40: 497-503. PMID: 9604188, DOI: 10.1097/00043764-199805000-00014.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbalmingFemaleFuneral RitesHumansMaleMiddle AgedOccupational ExposureRisk AssessmentTuberculin TestTuberculosisConceptsTuberculin skin testTuberculin skin testingSkin testingSkin testAnnual tuberculin skin testingReactive tuberculin skin testHome employeesPast historyRisk assessment questionnaireTuberculin reactivityTuberculosis infectionTuberculosis riskTuberculosis casesTuberculosis preventionInfected individualsStudy participantsClose contactConvenience sampleRespiratory protectionJob categoriesAgeRiskRisk assessment studiesNumber of yearsHistory
1997
Comparison of a Tuberculin Interferon-γ Assay with the Tuberculin Skin Test in High-Risk Adults: Effect of Human Immunodeficiency Virus Infection
Converse P, Jones S, Astemborski J, Vlahov D, Graham N. Comparison of a Tuberculin Interferon-γ Assay with the Tuberculin Skin Test in High-Risk Adults: Effect of Human Immunodeficiency Virus Infection. The Journal Of Infectious Diseases 1997, 176: 144-150. PMID: 9207360, DOI: 10.1086/514016.Peer-Reviewed Original ResearchConceptsTuberculin skin testHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionSkin testVirus infectionIFN-gammaNegative tuberculin skin testPositive tuberculin skin testInterferon-γ AssayTST induration diameterWhole bloodHigh-risk adultsIntravenous drug usersMycobacterium tuberculosis exposureWhole blood IFN-gammaIFN-gamma responsesCutaneous anergyMitogen controlSeronegative subjectsTuberculosis exposureHIV infectionTuberculin reactivityWhole heparinized bloodInduration diameterDrug users
1996
The Effect of Latent Mycobacterium tuberculosis Infection on Human Immunodeficiency Virus (HIV) Disease Progression and HIV RNA Load among Injecting Drug Users
Manoff S, Farzadegan H, Muñoz A, Astemborski J, Vlahov D, Rizzo R, Solomon L, Graham N. The Effect of Latent Mycobacterium tuberculosis Infection on Human Immunodeficiency Virus (HIV) Disease Progression and HIV RNA Load among Injecting Drug Users. The Journal Of Infectious Diseases 1996, 174: 299-308. PMID: 8699059, DOI: 10.1093/infdis/174.2.299.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) disease progressionLatent Mycobacterium tuberculosis infectionMycobacterium tuberculosis infectionTuberculosis infectionSkin testingDisease progressionDrug usersLatent M. tuberculosis infectionTuberculin positive casesTuberculin-negative controlsTuberculin-negative personsCD4 cell countCohort of HIVHIV RNA loadCD4 cell declineM. tuberculosis infectionTuberculin skin testingInjecting Drug UsersBaseline immune functionHIV concentrationHIV RNAActive tuberculosisHIV burdenHIV progressionRNA load
1995
Instability of Delayed-type Hypersensitivity Skin Test Anergy in Human Immunodeficiency Virus Infection
Caiaffa W, Graham N, Galai N, Rizzo R, Nelson K, Vlahov D. Instability of Delayed-type Hypersensitivity Skin Test Anergy in Human Immunodeficiency Virus Infection. JAMA Internal Medicine 1995, 155: 2111-2117. PMID: 7575072, DOI: 10.1001/archinte.1995.00430190107015.Peer-Reviewed Original ResearchConceptsHIV-seropositive subjectsHIV-seronegative subjectsCD4 cell countSkin test resultsDrug usersCell countDTH anergyDTH positivityDelayed-type hypersensitivity (DTH) skin testDelayed-type hypersensitivity anergyHuman immunodeficiency virus (HIV) infectionDTH skin testingSkin test anergyImmunodeficiency virus infectionCommunity-based cohortHuman immunodeficiency virusHypersensitivity skin testsCandida albicans antigenAnergy testingSerial skinCD4 cellsHIV statusSingle testSkin testingImmunodeficiency virus
1992
Prevalence of Tuberculin Positivity and Skin Test Anergy in HIV-1—Seropositive and —Seronegative Intravenous Drug Users
Graham N, Nelson K, Solomon L, Bonds M, Rizzo R, Scavotto J, Astemborski J, Vlahov D. Prevalence of Tuberculin Positivity and Skin Test Anergy in HIV-1—Seropositive and —Seronegative Intravenous Drug Users. JAMA 1992, 267: 369-373. PMID: 1727959, DOI: 10.1001/jama.1992.03480030047035.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHIV-1 seropositivesSkin test anergyHIV-1 seropositive groupSeronegative intravenous drug usersTuberculin positivityLymphocyte countPPD positivityHIV-1-seropositive intravenous drug usersPPD tuberculinDrug usersHuman immunodeficiency virus serostatusSeropositive intravenous drug usersHIV-1 seropositive patientsTuberculin skin test resultsHIV-1 seronegativeHIV-1 seronegativesPPD test resultsHIV-1 seropositivityDelayed-type hypersensitivityCommunity-based cohortSkin test resultsYears of agePositive test resultsInverse linear trend
1990
Coinfection with tuberculosis and HIV-1 in male prison inmates.
Salive M, Vlahov D, Brewer T. Coinfection with tuberculosis and HIV-1 in male prison inmates. Public Health Reports 1990, 105: 307-10. PMID: 2113691, PMCID: PMC1580008.Peer-Reviewed Original ResearchConceptsHIV-1HIV-1 antibody testingHuman immunodeficiency virus type 1Latent HIV-1 infectionImmunodeficiency virus type 1HIV-1 infectionVirus type 1Case-control designAnergy testingTB infectionAntibody testingMantoux testingElevated riskSignificant associationPast exposureTuberculosisType 1InfectionState prison systemMale prison inmatesAssociationPrison inmatesMale inmatesIntake samplesAdmission