2020
The association between anti-Müllerian hormone and vitamin 25(OH)D serum levels and polycystic ovarian syndrome in adolescent females
Simpson S, Seifer DB, Shabanova V, Lynn AY, Howe C, Rowe E, Caprio S, Vash-Margita A. The association between anti-Müllerian hormone and vitamin 25(OH)D serum levels and polycystic ovarian syndrome in adolescent females. Reproductive Biology And Endocrinology 2020, 18: 118. PMID: 33218348, PMCID: PMC7679991, DOI: 10.1186/s12958-020-00676-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnti-Mullerian HormoneFemaleHumansPolycystic Ovary SyndromeRegression AnalysisRetrospective StudiesRisk FactorsVitamin DYoung AdultConceptsPolycystic ovarian syndromeRotterdam diagnostic criteriaNon-PCOS groupMedian AMHOvarian syndromePCOS groupDiagnostic criteriaAnti-Müllerian hormone levelsAdolescent femalesRetrospective chart reviewTraditional clinical markersAnti-Müllerian hormoneCross-sectional studyWilcoxon rank sum testSignificant unadjusted differencesRank sum testD deficiencyChart reviewClinical featuresEndocrinology clinicSerum levelsAdjusted analysisUnadjusted comparisonsInsurance typeSurrogate marker
1996
Effects of fetal number and multifetal reduction on length of in vitro fertilization pregnancies.
Haning RV, Seifer DB, Wheeler CA, Frishman GN, Silver H, Pierce DJ. Effects of fetal number and multifetal reduction on length of in vitro fertilization pregnancies. Obstetrics And Gynecology 1996, 87: 964-8. PMID: 8649707, DOI: 10.1016/0029-7844(96)00059-2.Peer-Reviewed Original ResearchConceptsDuration of gestationMultifetal reductionFertilization pregnanciesMultifetal pregnancy reductionIVF pregnanciesTriplet pregnanciesMultiple gestationsMean gestationIVF programPregnancy reductionViable fetusesMore fetusesFetal numberPregnancyGestationWeeksFetusesRegression analysisDurationSpontaneous reductionNatural causesTwinsWomen
1994
Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins
Haning RV, Hua JJ, Hackett RJ, Wheeler CA, Frishman GN, Seifer DB, Dahl CA, Burger HG. Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 145-149. PMID: 8288697, DOI: 10.1210/jcem.78.1.8288697.Peer-Reviewed Original ResearchConceptsNumber of oocytesAnovulatory subjectsSerum inhibinAnovulatory ovariesSerum concentrationsNormal subjectsSerum DS concentrationSerum inhibin concentrationsAdministration of gonadotropinSecretion of inhibinResidual serum samplesDuration of treatmentAnovulatory patientsGonadotropin therapyInhibin concentrationsInhibin secretionPatient ageFertilization cyclesGonadotropin treatmentLH dosesFollicular functionHCG treatmentInhibinAverage durationSerum samples
1993
Comparison of persistent ectopic pregnancy after laparoscopic salpingostomy versus salpingostomy at laparotomy for ectopic pregnancy.
Seifer DB, Gutmann JN, Grant WD, Kamps CA, DeCherney AH. Comparison of persistent ectopic pregnancy after laparoscopic salpingostomy versus salpingostomy at laparotomy for ectopic pregnancy. Obstetrics And Gynecology 1993, 81: 378-82. PMID: 8437790.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesFemaleHumansIncidenceLaparoscopyLaparotomyPregnancyPregnancy, TubalRegression AnalysisRetrospective StudiesRisk FactorsSalpingostomyConceptsPersistent ectopic pregnancyAmpullary ectopic pregnancyEctopic pregnancyLaparoscopic salpingostomyYale-New Haven HospitalConfidence interval (CI) 1.1Days of amenorrheaStepwise logistic regressionEctopic sizeLaparoscopic approachMedical recordsOdds ratioLaparotomySalpingostomyPregnancyLogistic regressionWomenAmenorrheaPatientsHospitalGonadotropin-releasing hormone agonist-induced differences in granulosa cell cycle kinetics are associated with alterations in follicular fluid müllerian-inhibiting substance and androgen content
Seifer DB, MacLaughlin DT, Penzias AS, Behrman HR, Asmundson L, Donahoe PK, Haning RV, Flynn SD. Gonadotropin-releasing hormone agonist-induced differences in granulosa cell cycle kinetics are associated with alterations in follicular fluid müllerian-inhibiting substance and androgen content. The Journal Of Clinical Endocrinology & Metabolism 1993, 76: 711-714. PMID: 8445031, DOI: 10.1210/jcem.76.3.8445031.Peer-Reviewed Original ResearchConceptsHuman menopausal gonadotropinCell cycle kineticsProliferative indexGranulosa cellsFollicular fluidControl groupCycle kineticsGnRH analogue leuprolideOvulation induction regimensFollicular fluid contentMüllerian-inhibiting substanceHuman granulosa cellsLuteinized granulosa cellsCI (3.2-3.6) PInduction regimensMenopausal gonadotropinOocyte retrievalAndrogen contentGnRHSpecific growth factorsFlow cytometryGrowth factorFolliclesFluid contentOne-way analysis
1992
Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen
Seifer DB, Honig J, Penzias AS, Lavy G, Nadkarni PM, Jones EE, DeCherney AH, Flynn SD. Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen. The Journal Of Clinical Endocrinology & Metabolism 1992, 75: 636-640. PMID: 1639962, DOI: 10.1210/jcem.75.2.1639962.Peer-Reviewed Original ResearchConceptsHuman menopausal gonadotropinOvulation induction regimenGreater proliferative indexInduction regimenLeuprolide acetateProliferative indexGranulosa cellsGroup IGroup IIGroup IIIAmpules of hMGFunction of ageFlow cytometryDay of hCGProspective cohort studyGroup of patientsHuman granulosa cellsChronological ageMenopausal gonadotropinCohort studyOvulation inductionSerum FSHSignificant independent influenceOutcome measuresWomen's age
1990
Persistent ectopic pregnancy following laparoscopic linear salpingostomy.
Seifer DB, Gutmann JN, Doyle MB, Jones EE, Diamond MP, DeCherney AH. Persistent ectopic pregnancy following laparoscopic linear salpingostomy. Obstetrics And Gynecology 1990, 76: 1121-5. PMID: 1700350.Peer-Reviewed Original ResearchConceptsPersistent ectopic pregnancyEctopic pregnancyLaparoscopic salpingostomyMultivariate stepwise logistic regressionYale-New Haven HospitalBeta-hCG titersClose postoperative surveillanceLaparoscopic linear salpingostomyDays of amenorrheaStepwise logistic regressionIpsilateral tubeLinear salpingostomyPostoperative surveillanceRepeat surgerySurgical approachComplete salpingectomySalpingostomyPregnancyConservative proceduresLogistic regressionParticular cautionPatientsEctopicWomenSalpingectomy
1986
A critical reassessment of second‐look laparotomy in epithelial ovarian carcinoma
Miller D, Ballon S, Teng N, Seifer D, Soriero O. A critical reassessment of second‐look laparotomy in epithelial ovarian carcinoma. Cancer 1986, 57: 530-535. PMID: 3942985, DOI: 10.1002/1097-0142(19860201)57:3<530::aid-cncr2820570321>3.0.co;2-5.Peer-Reviewed Original ResearchMeSH KeywordsCarcinomaFemaleHumansLaparotomyMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingOvarian NeoplasmsPrognosisRegression AnalysisConceptsSecond-look laparotomyEpithelial ovarian carcinomaOvarian carcinomaPersistent tumorSecond-line salvage therapyMultivariate logistic regression analysisPersistent ovarian carcinomaComplete clinical responseComplete pathologic responseFirst-line chemotherapyFirst-line therapyEvidence of recurrenceLarge residual tumorRisk of recurrenceLogistic regression analysisDisease-free statusCurative intentSalvage therapyAdjunctive therapyClinical responsePathologic evidencePathologic responseMicroscopic diseaseResidual tumorGross tumor