Increasing Hypothalamic Arcuate Nucleus Glial Peroxidase Activity in Aging Female Rats Is Reduced by an Antiestrogen and a Gonadotropin-Releasing Hormone Agonist
Seifer D, Roa-Peña L, Keefe D, Zhang H, Goodman S, Jones E, Naftolin F. Increasing Hypothalamic Arcuate Nucleus Glial Peroxidase Activity in Aging Female Rats Is Reduced by an Antiestrogen and a Gonadotropin-Releasing Hormone Agonist. Menopause The Journal Of The North American Menopause Society 1994, 1: 83-90. DOI: 10.1097/00042192-199400120-00005.Peer-Reviewed Original ResearchMonths of ageFemale ratsGoserelin acetate depotPosterior periventricular areasComputerized image analyzerAge-related increaseDiaminobenzidine tetrahydrochloridePeriventricular areaArcuate nucleusGoserelin acetateEndogenous estrogensHypothalamic sectionsControl groupSuper agonistReproductive agingMonthsRatsPeroxidase activityDAB reactionAgeGroupImplantsAnimalsImage analyzerSerial sectioning