2024
Ovarian Aging and Fertility
Seifer D, Feinberg E, Hsu A. Ovarian Aging and Fertility. JAMA 2024, 332 PMID: 39470648, DOI: 10.1001/jama.2024.18207.Peer-Reviewed Original ResearchOvarian agingInfertility
2022
Age-related changes in Folliculogenesis and potential modifiers to improve fertility outcomes - A narrative review
Esencan E, Beroukhim G, Seifer D. Age-related changes in Folliculogenesis and potential modifiers to improve fertility outcomes - A narrative review. Reproductive Biology And Endocrinology 2022, 20: 156. PMID: 36397149, PMCID: PMC9670479, DOI: 10.1186/s12958-022-01033-x.Peer-Reviewed Original ResearchConceptsInsulin-like growth factor-1Vascular endothelial growth factorAge-related changesAntimullerian hormoneFertility outcomesIndividual studiesGrowth factor-1Endothelial growth factorObstetrical outcomesVitamin DOocyte quantityOvarian agingFollicular depletionFollicular fluidIntraovarian regulatorsRodent studiesHealthy oocytesNarrative reviewReproductive agingPotential modifiersCumulus cellsGrowth factorFactor 1Mitochondrial functionOutcomes
2014
Is AMH a regulator of follicular atresia?
Seifer DB, Merhi Z. Is AMH a regulator of follicular atresia? Journal Of Assisted Reproduction And Genetics 2014, 31: 1403-1407. PMID: 25193290, PMCID: PMC4389943, DOI: 10.1007/s10815-014-0328-7.Peer-Reviewed Original ResearchConceptsFollicular atresiaNatural ovarian agingPolycystic ovary syndromeOnset of menopausePremature ovarian insufficiencyTreatment of PCOSDifferent patient populationsBasic science studiesTiming of onsetOvary syndromePatient populationOvarian agingOvarian failureHuman ovaryTreatment strategiesAMH productionOvarian insufficiencyIntraovarian regulatorsGrowth factorCellular originCritical growth factorsCancer therapyMenopauseAtresiaAMH