Current concepts of β-endorphin physiology in female reproductive dysfunction
Wallach E, Seifer D, Collins R. Current concepts of β-endorphin physiology in female reproductive dysfunction. Fertility And Sterility 1990, 54: 757-771. PMID: 2226908, DOI: 10.1016/s0015-0282(16)53928-4.Peer-Reviewed Original ResearchConceptsEndogenous opioid peptidesBeta-endorphinReproductive dysfunctionOpioid peptidesPulsatile GnRH releasePolycystic ovarian syndromeBeta-endorphin levelsFemale reproductive dysfunctionExercise-associated amenorrheaNormal menstrual cycleOnset of pubertyGnRH releaseOvarian syndromeMenstrual cyclePeripheral levelsDopaminergic pathwaysPathophysiological processesPulsatile releaseSpecific disordersDysfunctionParticular disorderCurrent conceptsPrecise mechanismAmenorrheaClinical application