Neurotrophin-4/5 and Neurotrophin-3 Are Present within the Human Ovarian Follicle but Appear to Have Different Paracrine/Autocrine Functions
Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF. Neurotrophin-4/5 and Neurotrophin-3 Are Present within the Human Ovarian Follicle but Appear to Have Different Paracrine/Autocrine Functions. The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 4569-4571. PMID: 12364436, DOI: 10.1210/jc.2002-020499.Peer-Reviewed Original ResearchConceptsBrain-derived neurotrophic factorNeurotrophin-3Human ovarian folliclesNT-4/5Follicular fluidOvarian folliclesNeurotrophin-4/5Paracrine/autocrine functionsTrk C receptorOocyte maturationSoluble polypeptide growth factorsFollicles of womenFollicular fluid samplesHuman follicular fluid samplesHuman follicular fluidPolar body extrusionMouse immature oocytesMammalian nervous systemMouse oocytesBDNF receptorTrk BNeurotrophic factorPolypeptide growth factorsFirst polar body extrusionNeurotrophin ligands